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In-silico drug repurposing study predicts the combination of pirfenidone and melatonin as a promising candidate therapy to reduce SARS-CoV-2 infection progression and respiratory distress caused by cytokine storm

PloS one, 2020-10, Vol.15 (10), p.e0240149-e0240149

2020

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Artificial intelligence assessment of the potential of tocilizumab along with corticosteroids therapy for the management of COVID-19 evoked acute respiratory distress syndrome

PloS one, 2023-02, Vol.18 (2), p.e0280677-e0280677

2023

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Application of systems biology to identify pharmacological mechanisms of thrombotic microangiopathy evoked by combined activated prothrombin complex concentrate and emicizumab

Scientific reports, 2023-06, Vol.13 (1), p.10078-10078, Article 10078

2023

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Aflibercept Off-Target Effects in Diabetic Macular Edema: An In Silico Modeling Approach

International journal of molecular sciences, 2024-04, Vol.25 (7), p.3621

2024

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An in silico approach to identify early damage biomarker candidates in metachromatic leukodystrophy

Molecular genetics and metabolism reports, 2023-06, Vol.35, p.100974-100974, Article 100974

2023

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Identification of the Potential Molecular Mechanisms Linking RUNX1 Activity with Nonalcoholic Fatty Liver Disease, by Means of Systems Biology

Biomedicines, 2022-06, Vol.10 (6), p.1315

2022

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Aging Increases Hippocampal DUSP2 by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism

Frontiers in neurology, 2019-06, Vol.10, p.675-675

2019

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Application of artificial intelligence to predict protein biomarker candidates for the assessment of prognosis in patients with metachromatic leukodystrophy

Molecular genetics and metabolism, 2022-02, Vol.135 (2), p.S49-S49

2022

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Unveiling chronic spontaneous urticaria pathophysiology through systems biology

Journal of allergy and clinical immunology, 2023-04, Vol.151 (4), p.1005-1014

2023

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Current approaches for the recreation of cardiac ischaemic environment in vitro

International journal of pharmaceutics, 2023-02, Vol.632, p.122589-122589, Article 122589

2023

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Benefits of cryopreservation as long-term storage method of encapsulated cardiosphere-derived cells for cardiac therapy: A biomechanical analysis

International journal of pharmaceutics, 2021-09, Vol.607, p.121014-121014, Article 121014

2021

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Artificial intelligence assessment of the potential of tocilizumab along with corticosteroids therapy for the management of COVID-19 evoked acute respiratory distress syndrome

PloS one, 2023-01, Vol.18 (2), p.e0280677

2023

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Ceruletide and Alpha-1 Antitrypsin as a Novel Combination Therapy for Ischemic Stroke

Neurotherapeutics, 2022-03, Vol.19 (2), p.513-527

2022

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Female Sex, Age, and Unfavorable Response to Tumor Necrosis Factor Inhibitors in Patients With Axial Spondyloarthritis: Results of Statistical and Artificial Intelligence–Based Data Analyses of a National Multicenter Prospective Registry

Arthritis care & research (2010), 2023-01, Vol.75 (1), p.115-124

2023

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Abstract 1460: miRNome analyses reveal that activity of CAF expressed podoplanin in tumor microenvironment is modulated by exosome miRNAs involved in the PTEN-PI3K-AKT-mTOR signaling

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1460-1460

2017

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A Systems Biology- and Machine Learning-Based Study to Unravel Potential Therapeutic Mechanisms of Midostaurin as a Multitarget Therapy on FLT3-Mutated AML

BioMedInformatics, 2022-09, Vol.2 (3), p.375-397

2022

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Force Spectroscopy Imaging and Constriction Assays Reveal the Effects of Graphene Oxide on the Mechanical Properties of Alginate Microcapsules

ACS biomaterials science & engineering, 2021-01, Vol.7 (1), p.242-253

2021

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Generation of Self-Induced Myocardial Ischemia in Large-Sized Cardiac Spheroids without Alteration of Environmental Conditions Recreates Fibrotic Remodeling and Tissue Stiffening Revealed by Constriction Assays

ACS biomaterials science & engineering, 2024-02, Vol.10 (2), p.987-997

2024

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Signaling networks in MS: A systems-based approach to developing new pharmacological therapies

Multiple sclerosis, 2015-02, Vol.21 (2), p.138-146

2015

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In-silico drug repurposing study predicts the combination of pirfenidone and melatonin as a promising candidate therapy to reduce SARS-CoV-2 infection progression and respiratory distress caused by cytokine storm

PloS one, 2020-01, Vol.15 (10), p.e0240149

2020

Volltextzugriff (PDF)

Systems biology applied to non-alcoholic fatty liver disease (NAFLD): treatment selection based on the mechanism of action of nutraceuticals

Nutrafoods, 2014, Vol.13 (2), p.61-68

2014

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Mendelian randomization analysis for attention deficit/hyperactivity disorder: studying a broad range of exposures and outcomes

International journal of epidemiology, 2023-04, Vol.52 (2), p.386-402

2023

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A quantitative assessment of the eating capability in the elderly individuals

Physiology & behavior, 2015-08, Vol.147, p.274-281

2015

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Genetic overlap and causality between substance use disorder and attention‐deficit and hyperactivity disorder

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2021-04, Vol.186 (3), p.140-150

2021

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Gut microbiota signature in treatment-naïve attention-deficit/hyperactivity disorder

Translational psychiatry, 2021-07, Vol.11 (1), p.382-7, Article 382

2021

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In-silico drug repurposing study predicts the combination of pirfenidone and melatonin as a promising candidate therapy to reduce SARS-CoV-2 infection progression and respiratory distress caused by cytokine storm

Artificial intelligence assessment of the potential of tocilizumab along with corticosteroids therapy for the management of COVID-19 evoked acute respiratory distress syndrome

Application of systems biology to identify pharmacological mechanisms of thrombotic microangiopathy evoked by combined activated prothrombin complex concentrate and emicizumab

Aflibercept Off-Target Effects in Diabetic Macular Edema: An In Silico Modeling Approach

An in silico approach to identify early damage biomarker candidates in metachromatic leukodystrophy

Identification of the Potential Molecular Mechanisms Linking RUNX1 Activity with Nonalcoholic Fatty Liver Disease, by Means of Systems Biology

Aging Increases Hippocampal DUSP2 by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism

Application of artificial intelligence to predict protein biomarker candidates for the assessment of prognosis in patients with metachromatic leukodystrophy

Unveiling chronic spontaneous urticaria pathophysiology through systems biology

Current approaches for the recreation of cardiac ischaemic environment in vitro

Benefits of cryopreservation as long-term storage method of encapsulated cardiosphere-derived cells for cardiac therapy: A biomechanical analysis

Artificial intelligence assessment of the potential of tocilizumab along with corticosteroids therapy for the management of COVID-19 evoked acute respiratory distress syndrome

Ceruletide and Alpha-1 Antitrypsin as a Novel Combination Therapy for Ischemic Stroke

Female Sex, Age, and Unfavorable Response to Tumor Necrosis Factor Inhibitors in Patients With Axial Spondyloarthritis: Results of Statistical and Artificial Intelligence–Based Data Analyses of a National Multicenter Prospective Registry

Abstract 1460: miRNome analyses reveal that activity of CAF expressed podoplanin in tumor microenvironment is modulated by exosome miRNAs involved in the PTEN-PI3K-AKT-mTOR signaling

A Systems Biology- and Machine Learning-Based Study to Unravel Potential Therapeutic Mechanisms of Midostaurin as a Multitarget Therapy on FLT3-Mutated AML

Force Spectroscopy Imaging and Constriction Assays Reveal the Effects of Graphene Oxide on the Mechanical Properties of Alginate Microcapsules

Generation of Self-Induced Myocardial Ischemia in Large-Sized Cardiac Spheroids without Alteration of Environmental Conditions Recreates Fibrotic Remodeling and Tissue Stiffening Revealed by Constriction Assays

Signaling networks in MS: A systems-based approach to developing new pharmacological therapies

In-silico drug repurposing study predicts the combination of pirfenidone and melatonin as a promising candidate therapy to reduce SARS-CoV-2 infection progression and respiratory distress caused by cytokine storm

Systems biology applied to non-alcoholic fatty liver disease (NAFLD): treatment selection based on the mechanism of action of nutraceuticals

Mendelian randomization analysis for attention deficit/hyperactivity disorder: studying a broad range of exposures and outcomes

A quantitative assessment of the eating capability in the elderly individuals

Genetic overlap and causality between substance use disorder and attention‐deficit and hyperactivity disorder

Gut microbiota signature in treatment-naïve attention-deficit/hyperactivity disorder

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