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Evaluation of long acting GLP1R/GCGR agonist in a DIO and biopsy-confirmed mouse model of NASH suggest a beneficial role of GLP-1/glucagon agonism in NASH patients

Molecular metabolism (Germany), 2024-01, Vol.79, p.101850-101850, Article 101850

2024

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Differential Effects of Dietary Components on Glucose Intolerance and Non-Alcoholic Steatohepatitis

Nutrients, 2021-07, Vol.13 (8), p.2523

2021

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Strontium is a biased agonist of the calcium-sensing receptor in rat medullary thyroid carcinoma 6-23 cells

The Journal of pharmacology and experimental therapeutics, 2012-12, Vol.343 (3), p.638-649

2012

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Vitamin C Deficiency May Delay Diet-Induced NASH Regression in the Guinea Pig

Antioxidants, 2021-12, Vol.11 (1), p.69

2021

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Modelling Nonalcoholic Steatohepatitis In Vivo—A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model

Biomedicines, 2021-09, Vol.9 (9), p.1198

2021

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Humanized mouse model of skin inflammation is characterized by disturbed keratinocyte differentiation and influx of IL-17A producing T cells

PloS one, 2012-10, Vol.7 (10), p.e45509

2012

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Toxicity of nutritionally available selenium compounds in primary and transformed hepatocytes

Toxicology (Amsterdam), 2004-09, Vol.201 (1), p.21-30

2004

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Metabolic depletion of ATP by fructose inversely controls CD95- and tumor necrosis factor receptor 1-mediated hepatic apoptosis

The Journal of experimental medicine, 2000-06, Vol.191 (11), p.1975-1986

2000

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Glutathione Dependence of Caspase-8 Activation at the Death-inducing Signaling Complex

The Journal of biological chemistry, 2002-02, Vol.277 (7), p.5588-5595

2002

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ATP-depleting carbohydrates prevent tumor necrosis factor receptor 1-dependent apoptotic and necrotic liver injury in mice

The Journal of pharmacology and experimental therapeutics, 2007-06, Vol.321 (3), p.875-883

2007

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Tumor necrosis factor: how to make a killer molecule tumor-specific?

Current cancer drug targets, 2005-09, Vol.5 (6), p.381-392

2005

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Choline-deficient, high-fat diet-induced MASH in Göttingen Minipigs: characterization and effects of a chow reversal period

American journal of physiology: Gastrointestinal and liver physiology, 2024-10, Vol.327 (4), p.G571-G585

2024

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FRI-305-Long acting GLP-1/Glucagon co-agonist ameliorates steatosis, inflammation and fibrogenesis in a rodent model of NASH

Journal of hepatology, 2019-04, Vol.70 (1), p.e529-e530

2019

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Molecular drivers of non-alcoholic steatohepatitis are sustained in mild-to-late fibrosis progression in a guinea pig model

Molecular genetics and genomics : MGG, 2019-06, Vol.294 (3), p.649-661

2019

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1810-P: Triple Combination Therapy of GLP-1 Receptor Agonist Semaglutide with an FXR Agonist and AC Inhibitor Reverses Nonalcoholic Steatohepatitis (NASH) in Diet-Induced and Biopsy-Confirmed Mice

Diabetes (New York, N.Y.), 2020-06, Vol.69 (Supplement_1)

2020

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1813-P: Coadministration of a GLP-1/Glucagon Receptor Agonist with an FXR Agonist and ACC Inhibitor Reverses Nonalcoholic Steatohepatitis (NASH) in Diet-Induced and Biopsy-Confirmed Mice

Diabetes (New York, N.Y.), 2020-06, Vol.69 (Supplement_1)

2020

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The effect of acetylsalicylic acid and pentoxifylline in guinea pigs with non‐alcoholic steatohepatitis

Basic & clinical pharmacology & toxicology, 2021-04, Vol.128 (4), p.583-593

2021

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NASH-inducing Diets in Göttingen Minipigs

Journal of clinical and experimental hepatology, 2020-05, Vol.10 (3), p.211-221

2020

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Defined inflammatory states in astrocyte cultures: correlation with susceptibility towards CD95‐driven apoptosis

Journal of neurochemistry, 2004-01, Vol.88 (1), p.181-193

2004

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CXCR6 is expressed on T cells in both T helper type 1 (Th1) inflammation and allergen-induced Th2 lung inflammation but is only a weak mediator of chemotaxis

Immunology, 2007-08, Vol.121 (4), p.555-564

2007

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Differing Requirements for CCR4, E-Selectin, and alpha 4 beta 1 for the Migration of Memory CD4 and Activated T Cells to Dermal Inflammation

The Journal of immunology (1950), 2012-07, Vol.189 (1), p.337-346

2012

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Elevated numbers of SCART1 + γδ T cells in skin inflammation and inflammatory bowel disease

Molecular immunology, 2010-05, Vol.47 (9), p.1710-1718

2010

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Differing requirements for CCR4, E-selectin, and α4β1 for the migration of memory CD4 and activated T cells to dermal inflammation

The Journal of immunology (1950), 2012-07, Vol.189 (1), p.337-346

2012

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Elevated numbers of SCART1 super(+) gd T cells in skin inflammation and inflammatory bowel disease

Molecular immunology, 2010-05, Vol.47 (9), p.1710-1718

2010

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Kupffer Cell-Expressed Membrane-Bound TNF Mediates Melphalan Hepatotoxicity via Activation of Both TNF Receptors

The Journal of immunology (1950), 2005-09, Vol.175 (6), p.4076-4083

2005

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Evaluation of long acting GLP1R/GCGR agonist in a DIO and biopsy-confirmed mouse model of NASH suggest a beneficial role of GLP-1/glucagon agonism in NASH patients

Differential Effects of Dietary Components on Glucose Intolerance and Non-Alcoholic Steatohepatitis

Strontium is a biased agonist of the calcium-sensing receptor in rat medullary thyroid carcinoma 6-23 cells

Vitamin C Deficiency May Delay Diet-Induced NASH Regression in the Guinea Pig

Modelling Nonalcoholic Steatohepatitis In Vivo—A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model

Humanized mouse model of skin inflammation is characterized by disturbed keratinocyte differentiation and influx of IL-17A producing T cells

Toxicity of nutritionally available selenium compounds in primary and transformed hepatocytes

Metabolic depletion of ATP by fructose inversely controls CD95- and tumor necrosis factor receptor 1-mediated hepatic apoptosis

Glutathione Dependence of Caspase-8 Activation at the Death-inducing Signaling Complex

ATP-depleting carbohydrates prevent tumor necrosis factor receptor 1-dependent apoptotic and necrotic liver injury in mice

Tumor necrosis factor: how to make a killer molecule tumor-specific?

Choline-deficient, high-fat diet-induced MASH in Göttingen Minipigs: characterization and effects of a chow reversal period

FRI-305-Long acting GLP-1/Glucagon co-agonist ameliorates steatosis, inflammation and fibrogenesis in a rodent model of NASH

Molecular drivers of non-alcoholic steatohepatitis are sustained in mild-to-late fibrosis progression in a guinea pig model

1810-P: Triple Combination Therapy of GLP-1 Receptor Agonist Semaglutide with an FXR Agonist and AC Inhibitor Reverses Nonalcoholic Steatohepatitis (NASH) in Diet-Induced and Biopsy-Confirmed Mice

1813-P: Coadministration of a GLP-1/Glucagon Receptor Agonist with an FXR Agonist and ACC Inhibitor Reverses Nonalcoholic Steatohepatitis (NASH) in Diet-Induced and Biopsy-Confirmed Mice

The effect of acetylsalicylic acid and pentoxifylline in guinea pigs with non‐alcoholic steatohepatitis

NASH-inducing Diets in Göttingen Minipigs

Defined inflammatory states in astrocyte cultures: correlation with susceptibility towards CD95‐driven apoptosis

CXCR6 is expressed on T cells in both T helper type 1 (Th1) inflammation and allergen-induced Th2 lung inflammation but is only a weak mediator of chemotaxis

Differing Requirements for CCR4, E-Selectin, and alpha 4 beta 1 for the Migration of Memory CD4 and Activated T Cells to Dermal Inflammation

Elevated numbers of SCART1 + γδ T cells in skin inflammation and inflammatory bowel disease

Differing requirements for CCR4, E-selectin, and α4β1 for the migration of memory CD4 and activated T cells to dermal inflammation

Elevated numbers of SCART1 super(+) gd T cells in skin inflammation and inflammatory bowel disease

Kupffer Cell-Expressed Membrane-Bound TNF Mediates Melphalan Hepatotoxicity via Activation of Both TNF Receptors

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