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Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms

Redox biology, 2020-01, Vol.28, p.101388, Article 101388

2020

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Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (13), p.5139-5144

2013

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GPx2 suppression of H2O2 stress links the formation of differentiated tumor mass to metastatic capacity in colorectal cancer

Cancer research (Chicago, Ill.), 2014-11, Vol.74 (22), p.6717-6730

2014

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Co-cultures of colon cancer cells and cancer-associated fibroblasts recapitulate the aggressive features of mesenchymal-like colon cancer

Frontiers in immunology, 2023-05, Vol.14, p.1053920-1053920

2023

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KIT promotes tumor stroma formation and counteracts tumor-suppressive TGFβ signaling in colorectal cancer

Cell death & disease, 2022-07, Vol.13 (7), p.617-10, Article 617

2022

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Differential anti-tumour effects of MTH1 inhibitors in patient-derived 3D colorectal cancer cultures

Scientific reports, 2019-01, Vol.9 (1), p.819-819, Article 819

2019

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Loss of Neuropilin-2 in Murine Mesenchymal-like Colon Cancer Organoids Causes Mesenchymal-to-Epithelial Transition and an Acquired Dependency on Insulin-Receptor Signaling and Autophagy

Cancers, 2022-01, Vol.14 (3), p.671

2022

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Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

Journal for immunotherapy of cancer, 2022-12, Vol.10 (12), p.e005345

2022

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ZNF423 Is Critically Required for Retinoic Acid-Induced Differentiation and Is a Marker of Neuroblastoma Outcome

Cancer cell, 2009-04, Vol.15 (4), p.328-340

2009

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Activation of FoxM1 during G2 Requires Cyclin A/Cdk-Dependent Relief of Autorepression by the FoxM1 N-Terminal Domain

Molecular and Cellular Biology, 2008-05, Vol.28 (9), p.3076-3087

2008

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FoxM1 is degraded at mitotic exit in a Cdh1-dependent manner

Cell cycle (Georgetown, Tex.), 2008-09, Vol.7 (17), p.2720-2726

2008

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Mismatch Repair Status in Patient-Derived Colorectal Cancer Organoids Does Not Affect Intrinsic Tumor Cell Sensitivity to Systemic Therapy

Cancers, 2021-10, Vol.13 (21), p.5434

2021

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IL-13 alters mucociliary differentiation and ciliary beating of human respiratory epithelial cells

The Journal of clinical investigation, 2001-12, Vol.108 (12), p.1817-1824

2001

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Differential expression and cellular distribution of centrin isoforms during human ciliated cell differentiation in vitro

Journal of cell science, 2000-04, Vol.113 ( Pt 8) (8), p.1355-1364

2000

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FoxM1: At the crossroads of ageing and cancer

Biochimica et biophysica acta, 2007, Vol.1775 (1), p.92-102

2007

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BRAFV600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-specific metastasis by stimulating glutathione synthesis

Cell reports (Cambridge), 2022-11, Vol.41 (9), p.111728-111728, Article 111728

2022

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FoxM1 is required for execution of the mitotic programme and chromosome stability

Nature cell biology, 2005-02, Vol.7 (2), p.126-136

2005

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Peritoneal metastases from colorectal cancer belong to Consensus Molecular Subtype 4 and are sensitised to oxaliplatin by inhibiting reducing capacity

British journal of cancer, 2022-06, Vol.126 (12), p.1824-1833

2022

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Stromal localization of inactive CD8 + T cells in metastatic mismatch repair deficient colorectal cancer

British journal of cancer, 2024-02, Vol.130 (2), p.213-223

2024

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Lymphatic Invasion of Plakoglobin-Dependent Tumor Cell Clusters Drives Formation of Polyclonal Lung Metastases in Colon Cancer

Gastroenterology (New York, N.Y. 1943), 2023-08, Vol.165 (2), p.429-444.e15

2023

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Long-Lived Human Lymphatic Endothelial Cells to Study Lymphatic Biology and Lymphatic Vessel/Tumor Coculture in a 3D Microfluidic Model

ACS biomaterials science & engineering, 2021-07, Vol.7 (7), p.3030-3042

2021

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Inhibition of RAF1 kinase activity restores apicobasal polarity and impairs tumour growth in human colorectal cancer

Gut, 2017-06, Vol.66 (6), p.1106-1115

2017

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Increased Levels of Oxidative Damage in Liver Metastases Compared with Corresponding Primary Colorectal Tumors: Association with Molecular Subtype and Prior Treatment

The American journal of pathology, 2018-10, Vol.188 (10), p.2369-2377

2018

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BRAF V600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-specific metastasis by stimulating glutathione synthesis

Cell reports (Cambridge), 2022-11, Vol.41 (9), p.111728

2022

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Increased Levels of Oxidative Damage in Liver Metastases Compared with Corresponding Primary Colorectal Tumors

The American journal of pathology, 2018-10, Vol.188 (10), p.2369-2377

2018

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Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms

Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis

GPx2 suppression of H2O2 stress links the formation of differentiated tumor mass to metastatic capacity in colorectal cancer

Co-cultures of colon cancer cells and cancer-associated fibroblasts recapitulate the aggressive features of mesenchymal-like colon cancer

KIT promotes tumor stroma formation and counteracts tumor-suppressive TGFβ signaling in colorectal cancer

Differential anti-tumour effects of MTH1 inhibitors in patient-derived 3D colorectal cancer cultures

Loss of Neuropilin-2 in Murine Mesenchymal-like Colon Cancer Organoids Causes Mesenchymal-to-Epithelial Transition and an Acquired Dependency on Insulin-Receptor Signaling and Autophagy

Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice

ZNF423 Is Critically Required for Retinoic Acid-Induced Differentiation and Is a Marker of Neuroblastoma Outcome

Activation of FoxM1 during G2 Requires Cyclin A/Cdk-Dependent Relief of Autorepression by the FoxM1 N-Terminal Domain

FoxM1 is degraded at mitotic exit in a Cdh1-dependent manner

Mismatch Repair Status in Patient-Derived Colorectal Cancer Organoids Does Not Affect Intrinsic Tumor Cell Sensitivity to Systemic Therapy

IL-13 alters mucociliary differentiation and ciliary beating of human respiratory epithelial cells

Differential expression and cellular distribution of centrin isoforms during human ciliated cell differentiation in vitro

FoxM1: At the crossroads of ageing and cancer

BRAFV600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-specific metastasis by stimulating glutathione synthesis

FoxM1 is required for execution of the mitotic programme and chromosome stability

Peritoneal metastases from colorectal cancer belong to Consensus Molecular Subtype 4 and are sensitised to oxaliplatin by inhibiting reducing capacity

Stromal localization of inactive CD8 + T cells in metastatic mismatch repair deficient colorectal cancer

Lymphatic Invasion of Plakoglobin-Dependent Tumor Cell Clusters Drives Formation of Polyclonal Lung Metastases in Colon Cancer

Long-Lived Human Lymphatic Endothelial Cells to Study Lymphatic Biology and Lymphatic Vessel/Tumor Coculture in a 3D Microfluidic Model

Inhibition of RAF1 kinase activity restores apicobasal polarity and impairs tumour growth in human colorectal cancer

Increased Levels of Oxidative Damage in Liver Metastases Compared with Corresponding Primary Colorectal Tumors: Association with Molecular Subtype and Prior Treatment

BRAF V600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-specific metastasis by stimulating glutathione synthesis

Increased Levels of Oxidative Damage in Liver Metastases Compared with Corresponding Primary Colorectal Tumors

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