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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

Nature (London), 2011-05, Vol.474 (7352), p.521-525

2011

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G Protein-Coupled Receptors Targeting Insulin Resistance, Obesity, and Type 2 Diabetes Mellitus

Pharmacological reviews, 2018-01, Vol.70 (1), p.39-67

2018

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Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists

Molecular cell, 2020-11, Vol.80 (3), p.485-500.e7

2020

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Comparative genotypic and phenotypic analysis of human peripheral blood monocytes and surrogate monocyte-like cell lines commonly used in metabolic disease research

PloS one, 2018-05, Vol.13 (5), p.e0197177-e0197177

2018

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New Advances in Targeting the Resolution of Inflammation: Implications for Specialized Pro-Resolving Mediator GPCR Drug Discovery

ACS pharmacology & translational science, 2020-02, Vol.3 (1), p.88-106

2020

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Progress in Structure Based Drug Design for G Protein-Coupled Receptors

Journal of medicinal chemistry, 2011-07, Vol.54 (13), p.4283-4311

2011

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Beyond antipsychotics: a twenty-first century update for preclinical development of schizophrenia therapeutics

Translational psychiatry, 2022-04, Vol.12 (1), p.147-11, Article 147

2022

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Structure-based development of a subtype-selective orexin 1 receptor antagonist

Proceedings of the National Academy of Sciences - PNAS, 2020-07, Vol.117 (30), p.18059-18067

2020

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Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits

British journal of pharmacology, 2024-07, Vol.181 (14), p.2114-2142

2024

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International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands

Pharmacological reviews, 2014-10, Vol.66 (4), p.918-947

2014

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Dynamic allostery governs cyclophilin A–HIV capsid interplay

Proceedings of the National Academy of Sciences - PNAS, 2015-11, Vol.112 (47), p.14617-14622

2015

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Characterization of a putative orexin receptor in Ciona intestinalis sheds light on the evolution of the orexin/hypocretin system in chordates

Scientific reports, 2024-04, Vol.14 (1), p.7690-7690, Article 7690

2024

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Supra‐physiological efficacy at GPCRs: superstition or super agonists?

British journal of pharmacology, 2013-05, Vol.169 (2), p.353-356

2013

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Serum Biomarker Panels for the Detection of Pancreatic Cancer

Clinical cancer research, 2011-02, Vol.17 (4), p.805-816

2011

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Divergent effects of strontium and calcium‐sensing receptor positive allosteric modulators (calcimimetics) on human osteoclast activity

British journal of pharmacology, 2018-11, Vol.175 (21), p.4095-4108

2018

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Allosteric agonists of 7TM receptors: expanding the pharmacological toolbox

Trends in pharmacological sciences (Regular ed.), 2006-09, Vol.27 (9), p.475-481

2006

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Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants

PloS one, 2016-01, Vol.11 (1), p.e0146846-e0146846

2016

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Efficient modeling and active learning discovery of biological responses

PloS one, 2013-12, Vol.8 (12), p.e83996-e83996

2013

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HARVESTMAN: a framework for hierarchical feature learning and selection from whole genome sequencing data

BMC bioinformatics, 2021-04, Vol.22 (1), p.174-174, Article 174

2021

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HIV‑1 Capsid Function Is Regulated by Dynamics: Quantitative Atomic-Resolution Insights by Integrating Magic-Angle-Spinning NMR, QM/MM, and MD

Journal of the American Chemical Society, 2016-10, Vol.138 (42), p.14066-14075

2016

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“We don’t want to run before we walk”: the attitudes of Australian stakeholders towards using psychedelics for mental health conditions

Public Health Research & Practice, 2023-09, Vol.33 (3)

2023

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Muscarinic acetylcholine receptors as CNS drug targets

Pharmacology & therapeutics (Oxford), 2008-02, Vol.117 (2), p.232-243

2008

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Discovering conformational sub-states relevant to protein function

PloS one, 2011-01, Vol.6 (1), p.e15827-e15827

2011

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SI preface: Neuropharmacology of addiction

British journal of pharmacology, 2024-09

2024

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Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure

Frontiers in pharmacology, 2021-03, Vol.12, p.628060

2021

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Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

G Protein-Coupled Receptors Targeting Insulin Resistance, Obesity, and Type 2 Diabetes Mellitus

Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists

Comparative genotypic and phenotypic analysis of human peripheral blood monocytes and surrogate monocyte-like cell lines commonly used in metabolic disease research

New Advances in Targeting the Resolution of Inflammation: Implications for Specialized Pro-Resolving Mediator GPCR Drug Discovery

Progress in Structure Based Drug Design for G Protein-Coupled Receptors

Beyond antipsychotics: a twenty-first century update for preclinical development of schizophrenia therapeutics

Structure-based development of a subtype-selective orexin 1 receptor antagonist

Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits

International Union of Basic and Clinical Pharmacology. XC. multisite pharmacology: recommendations for the nomenclature of receptor allosterism and allosteric ligands

Dynamic allostery governs cyclophilin A–HIV capsid interplay

Characterization of a putative orexin receptor in Ciona intestinalis sheds light on the evolution of the orexin/hypocretin system in chordates

Supra‐physiological efficacy at GPCRs: superstition or super agonists?

Serum Biomarker Panels for the Detection of Pancreatic Cancer

Divergent effects of strontium and calcium‐sensing receptor positive allosteric modulators (calcimimetics) on human osteoclast activity

Allosteric agonists of 7TM receptors: expanding the pharmacological toolbox

Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants

Efficient modeling and active learning discovery of biological responses

HARVESTMAN: a framework for hierarchical feature learning and selection from whole genome sequencing data

HIV‑1 Capsid Function Is Regulated by Dynamics: Quantitative Atomic-Resolution Insights by Integrating Magic-Angle-Spinning NMR, QM/MM, and MD

“We don’t want to run before we walk”: the attitudes of Australian stakeholders towards using psychedelics for mental health conditions

Muscarinic acetylcholine receptors as CNS drug targets

Discovering conformational sub-states relevant to protein function

SI preface: Neuropharmacology of addiction

Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure

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