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The targets of currently used antibacterial agents: lessons for drug discovery

Current pharmaceutical design, 2007-10, Vol.13 (30), p.3140-3154

2007

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The crystallization additive hexatungstotellurate promotes the crystallization of the HSP70 nucleotide binding domain into two different crystal forms

PloS one, 2018-06, Vol.13 (6), p.e0199639-e0199639

2018

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Genetic Analysis and Functional Characterization of the Streptococcus pneumoniae vic Operon

Infection and Immunity, 2002-11, Vol.70 (11), p.6121-6128

2002

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Multiple Heimaten – eine Thüringen-Reise

Informationen zur Raumentwicklung, 2019-01 (2)

2019

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Identification of SARS-CoV-2 Mpro inhibitors through deep reinforcement learning for drug design and computational chemistry approaches

RSC medicinal chemistry, 2024-06, Vol.15 (6), p.2146-2159

2024

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Fragment‐based screening targeting an open form of the SARS‐CoV‐2 main protease binding pocket

Acta crystallographica. Section D, Biological crystallography., 2024-02, Vol.80 (2), p.123-136

2024

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Identification of SARS-CoV-2 Mpro inhibitors through deep reinforcement learning for de novo drug design and computational chemistry approaches

RSC medicinal chemistry, 2024-06, Vol.15 (6), p.2146-2159

2024

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Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria

Journal of medicinal chemistry, 2020-01, Vol.63 (1), p.66-87

2020

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Optimization of LpxC Inhibitor Lead Compounds Focusing on Efficacy and Formulation for High Dose Intravenous Administration

Journal of medicinal chemistry, 2020-01, Vol.63 (1), p.88-102

2020

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Jahrbuch für Kulturpolitik 2019/20 : Thema: Kultur. Macht. Heimaten. Heimat als kulturpolitische Herausforderung (Edition 1)

1, 2020

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Identification and characterization of stationary phase inducible genes in Escherichia coli

Molecular microbiology, 1993-10, Vol.10 (2), p.407-420

1993

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OU-TÓPOS, unwirtlicher Ort: Verlasst das Land

Jahrbuch für Kulturpolitik 2019/20, 2020, Vol.17, p.341-346

2020

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TnTIN and TnTAP: Mini-Transposons for Site-Specific Proteolysis in vivo

Proceedings of the National Academy of Sciences - PNAS, 1997-11, Vol.94 (24), p.13111-13115

1997

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The Crystal Structure of E. coli 1-Deoxy- d-xylulose-5-phosphate Reductoisomerase in a Ternary Complex with the Antimalarial Compound Fosmidomycin and NADPH Reveals a Tight-binding Closed Enzyme Conformation

Journal of molecular biology, 2005-01, Vol.345 (1), p.115-127

2005

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Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity

Bioorganic & medicinal chemistry letters, 2012-11, Vol.22 (21), p.6705-6711

2012

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Sondierungen auf einem Siedlungsplatz der Trichterbecherkultur bei Hohen Schwarfs, Kr. Rostock

1987, 2021, Vol.32, Heft 3, p.117-125

2021

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Microarray-based identification of a novel Streptococcus pneumoniae regulon controlled by an autoinduced peptide

Journal of bacteriology, 2000-09, Vol.182 (17), p.4696-4703

2000

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The nIpD gene is located in an operon with rpoS on the Escherichia coli chromosome and encodes a novel lipoprotein with a potential function in ceil wall formation

Molecular microbiology, 1994-08, Vol.13 (4), p.733-743

1994

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Domain organization and molecular characterization of 13 two-component systems identified by genome sequencing of Streptococcus pneumoniae

Gene, 1999-09, Vol.237 (1), p.223-234

1999

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A continuous coupled enzyme assay for bacterial malonyl–CoA:acyl carrier protein transacylase (FabD)

Analytical biochemistry, 2003-08, Vol.319 (1), p.171-176

2003

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Osmotic regulation of rpoS-dependent genes in Escherichia coli

Journal of Bacteriology, 1993-01, Vol.175 (1), p.259-265

1993

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Posttranscriptional osmotic regulation of the sigma(s) subunit of RNA polymerase in Escherichia coli

Journal of Bacteriology, 1996-03, Vol.178 (6), p.1607-1613

1996

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Interplay between global regulators of Escherichia coli : effect of RpoS, Lrp and H‐NS on transcription of the gene osmC

Molecular microbiology, 1998-06, Vol.28 (5), p.971-980

1998

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The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation

Journal of molecular biology, 2005-01, Vol.345 (1), p.115-127

2005

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Identification of transcriptional start sites and the role of ppGpp in the expression of rpoS, the structural gene for the sigmaS subunit of RNA polymerase in Escherichia coli

Journal of bacteriology, 1995-08, Vol.177 (16), p.4676

1995

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The targets of currently used antibacterial agents: lessons for drug discovery

The crystallization additive hexatungstotellurate promotes the crystallization of the HSP70 nucleotide binding domain into two different crystal forms

Genetic Analysis and Functional Characterization of the Streptococcus pneumoniae vic Operon

Multiple Heimaten – eine Thüringen-Reise

Identification of SARS-CoV-2 Mpro inhibitors through deep reinforcement learning for drug design and computational chemistry approaches

Fragment‐based screening targeting an open form of the SARS‐CoV‐2 main protease binding pocket

Identification of SARS-CoV-2 Mpro inhibitors through deep reinforcement learning for de novo drug design and computational chemistry approaches

Discovery of Novel Inhibitors of LpxC Displaying Potent in Vitro Activity against Gram-Negative Bacteria

Optimization of LpxC Inhibitor Lead Compounds Focusing on Efficacy and Formulation for High Dose Intravenous Administration

Jahrbuch für Kulturpolitik 2019/20 : Thema: Kultur. Macht. Heimaten. Heimat als kulturpolitische Herausforderung (Edition 1)

Identification and characterization of stationary phase inducible genes in Escherichia coli

OU-TÓPOS, unwirtlicher Ort: Verlasst das Land

TnTIN and TnTAP: Mini-Transposons for Site-Specific Proteolysis in vivo

The Crystal Structure of E. coli 1-Deoxy- d-xylulose-5-phosphate Reductoisomerase in a Ternary Complex with the Antimalarial Compound Fosmidomycin and NADPH Reveals a Tight-binding Closed Enzyme Conformation

Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity

Sondierungen auf einem Siedlungsplatz der Trichterbecherkultur bei Hohen Schwarfs, Kr. Rostock

Microarray-based identification of a novel Streptococcus pneumoniae regulon controlled by an autoinduced peptide

The nIpD gene is located in an operon with rpoS on the Escherichia coli chromosome and encodes a novel lipoprotein with a potential function in ceil wall formation

Domain organization and molecular characterization of 13 two-component systems identified by genome sequencing of Streptococcus pneumoniae

A continuous coupled enzyme assay for bacterial malonyl–CoA:acyl carrier protein transacylase (FabD)

Osmotic regulation of rpoS-dependent genes in Escherichia coli

Posttranscriptional osmotic regulation of the sigma(s) subunit of RNA polymerase in Escherichia coli

Interplay between global regulators of Escherichia coli : effect of RpoS, Lrp and H‐NS on transcription of the gene osmC

The crystal structure of E.coli 1-deoxy-D-xylulose-5-phosphate reductoisomerase in a ternary complex with the antimalarial compound fosmidomycin and NADPH reveals a tight-binding closed enzyme conformation

Identification of transcriptional start sites and the role of ppGpp in the expression of rpoS, the structural gene for the sigmaS subunit of RNA polymerase in Escherichia coli

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