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Defining the unknowns for cell therapies in Parkinson's disease

Disease models & mechanisms, 2022-10, Vol.15 (10)

2022

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L-dopa-Dependent Effects of GLP-1R Agonists on the Survival of Dopaminergic Cells Transplanted into a Rat Model of Parkinson Disease

International journal of molecular sciences, 2021-11, Vol.22 (22), p.12346

2021

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L‐DOPA for Parkinson's disease—a bittersweet pill

The European journal of neuroscience, 2019-02, Vol.49 (3), p.384-398

Lane, Emma L.

2019

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Impaired cognitive and motor function are coincident with l-DOPA-induced dyskinesia in a model of Parkinson’s disease

Scientific reports, 2023-10, Vol.13 (1), p.17697-17697, Article 17697

2023

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Unilateral nigrostriatal 6-hydroxydopamine lesions in mice I: Motor impairments identify extent of dopamine depletion at three different lesion sites

Behavioural brain research, 2012-03, Vol.228 (1), p.30-43

2012

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Comparison of rating scales used to evaluate l -DOPA-induced dyskinesia in the 6-OHDA lesioned rat

Neurobiology of disease, 2013-02, Vol.50, p.142-150

2013

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Factors affecting the choice of first-line therapy in Parkinson’s disease patients in Wales: A population-based study

Saudi pharmaceutical journal, 2021-02, Vol.29 (2), p.206-212

2021

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Dopaminergic Progenitors Derived From Epiblast Stem Cells Function Similarly to Primary VM-Derived Progenitors When Transplanted Into a Parkinson's Disease Model

Frontiers in neuroscience, 2020-04, Vol.14, p.312-312

2020

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Pharmacological modulation of amphetamine-induced dyskinesia in transplanted hemi-parkinsonian rats

Neuropharmacology, 2012-10, Vol.63 (5), p.818-828

2012

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Brain Repair in a Unilateral Rat Model of Huntington's Disease: New Insights into Impairment and Restoration of Forelimb Movement Patterns

Cell transplantation, 2013-01, Vol.22 (10), p.1735-1751

2013

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Inhibition of 7α,26-dihydroxycholesterol biosynthesis promotes midbrain dopaminergic neuron development

iScience, 2024-01, Vol.27 (1), p.108670-108670, Article 108670

2024

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Spontaneous Graft‐Induced Dyskinesias Are Independent of 5‐HT Neurons and Levodopa Priming in a Model of Parkinson's Disease

Movement disorders, 2022-03, Vol.37 (3), p.613-619

2022

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PINK1-Dependent Mitophagy Inhibits Elevated Ubiquitin Phosphorylation Caused by Mitochondrial Damage

Journal of medicinal chemistry, 2023-06, Vol.66 (11), p.7645-7656

2023

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Human Embryonic Stem Cell-Derived Dopaminergic Grafts Alleviate L-DOPA Induced Dyskinesia

Journal of Parkinson's disease, 2022-01, Vol.12 (6), p.1881-1896

2022

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Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson’s disease

Brain, behavior, and immunity, 2017-03, Vol.61, p.155-164

2017

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Unilateral nigrostriatal 6-hydroxydopamine lesions in mice II: Predicting l-DOPA-induced dyskinesia

Behavioural brain research, 2012, Vol.226 (1), p.281-292

2012

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Neural grafting in Parkinson's disease unraveling the mechanisms underlying graft-induced dyskinesia

Progress in brain research, 2010, Vol.184, p.295

2010

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l-DOPA- and graft-induced dyskinesia following transplantation

Progress in Brain Research, 2012, Vol.200, p.143-168

2012

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Human stem cells for CNS repair

Cell and tissue research, 2008, Vol.331 (1), p.301-322

2008

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Clinical and Experimental Experiences of Graft-Induced Dyskinesia

International Review of Neurobiology, 2011, Vol.98, p.173-186

Lane, Emma L.

2011

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The effect of additional noradrenergic and serotonergic depletion on a lateralised choice reaction time task in rats with nigral 6-OHDA lesions

Experimental neurology, 2014-03, Vol.253, p.52-62

2014

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Potential cellular and regenerative approaches for the treatment of Parkinson's disease

Neuropsychiatric disease and treatment, 2008-10, Vol.4 (5), p.835-845

2008

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More than a participant in trials of cell and gene therapy: Hearing the voices of people living with neurodegenerative diseases

International review of neurobiology, 2022, Vol.166, p.281-312

2022

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Pre-treatment with dopamine agonists influence l-dopa mediated rotations without affecting abnormal involuntary movements in the 6-OHDA lesioned rat

Behavioural brain research, 2010-11, Vol.213 (1), p.66-72

2010

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Defining the unknowns for cell therapies in Parkinson's disease

L-dopa-Dependent Effects of GLP-1R Agonists on the Survival of Dopaminergic Cells Transplanted into a Rat Model of Parkinson Disease

L‐DOPA for Parkinson's disease—a bittersweet pill

Impaired cognitive and motor function are coincident with l-DOPA-induced dyskinesia in a model of Parkinson’s disease

Unilateral nigrostriatal 6-hydroxydopamine lesions in mice I: Motor impairments identify extent of dopamine depletion at three different lesion sites

Comparison of rating scales used to evaluate l -DOPA-induced dyskinesia in the 6-OHDA lesioned rat

Factors affecting the choice of first-line therapy in Parkinson’s disease patients in Wales: A population-based study

Dopaminergic Progenitors Derived From Epiblast Stem Cells Function Similarly to Primary VM-Derived Progenitors When Transplanted Into a Parkinson's Disease Model

Pharmacological modulation of amphetamine-induced dyskinesia in transplanted hemi-parkinsonian rats

Brain Repair in a Unilateral Rat Model of Huntington's Disease: New Insights into Impairment and Restoration of Forelimb Movement Patterns

Inhibition of 7α,26-dihydroxycholesterol biosynthesis promotes midbrain dopaminergic neuron development

Spontaneous Graft‐Induced Dyskinesias Are Independent of 5‐HT Neurons and Levodopa Priming in a Model of Parkinson's Disease

PINK1-Dependent Mitophagy Inhibits Elevated Ubiquitin Phosphorylation Caused by Mitochondrial Damage

Human Embryonic Stem Cell-Derived Dopaminergic Grafts Alleviate L-DOPA Induced Dyskinesia

Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson’s disease

Unilateral nigrostriatal 6-hydroxydopamine lesions in mice II: Predicting l-DOPA-induced dyskinesia

Neural grafting in Parkinson's disease unraveling the mechanisms underlying graft-induced dyskinesia

l-DOPA- and graft-induced dyskinesia following transplantation

Human stem cells for CNS repair

Clinical and Experimental Experiences of Graft-Induced Dyskinesia

The effect of additional noradrenergic and serotonergic depletion on a lateralised choice reaction time task in rats with nigral 6-OHDA lesions

Potential cellular and regenerative approaches for the treatment of Parkinson's disease

More than a participant in trials of cell and gene therapy: Hearing the voices of people living with neurodegenerative diseases

Patient and Public Involvement and Engagement in the Development of a Platform Clinical Trial for Parkinson’s Disease: An Evaluation Protocol

Pre-treatment with dopamine agonists influence l-dopa mediated rotations without affecting abnormal involuntary movements in the 6-OHDA lesioned rat

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