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A Coupled SYSTEM of Intracellular Ca2+ Clocks and Surface Membrane Voltage Clocks Controls the Timekeeping Mechanism of the Heartʼs Pacemaker

Circulation research, 2010-03, Vol.106 (4), p.659-673

2010

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Matrix Metalloproteinases Promote Arterial Remodeling in Aging, Hypertension, and Atherosclerosis

Hypertension (Dallas, Tex. 1979), 2015-04, Vol.65 (4), p.698-703

2015

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What keeps us ticking: a funny current, a calcium clock, or both?

Journal of molecular and cellular cardiology, 2009-08, Vol.47 (2), p.157-170

2009

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The Conundrum of Arterial Stiffness, Elevated Blood Pressure, and Aging

Current hypertension reports, 2015-02, Vol.17 (2), p.12-12, Article 12

2015

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Increased Drp1 Acetylation by Lipid Overload Induces Cardiomyocyte Death and Heart Dysfunction

Circulation research, 2020-02, Vol.126 (4), p.456-470

2020

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Resveratrol Prevents High Fat/Sucrose Diet-Induced Central Arterial Wall Inflammation and Stiffening in Nonhuman Primates

Cell metabolism, 2014-07, Vol.20 (1), p.183-190

2014

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Role of inflammation in the pathogenesis of arterial stiffness

Yonsei Medical Journal, 2012, 53(2), , pp.258-261

2012

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Aging-Associated Cardiovascular Changes and Their Relationship to Heart Failure

Heart failure clinics, 2012, Vol.8 (1), p.143-164

2012

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Biophysical Characterization of the Underappreciated and Important Relationship Between Heart Rate Variability and Heart Rate

Hypertension (Dallas, Tex. 1979), 2014-12, Vol.64 (6), p.1334-1343

2014

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Derivation and Validation of Diagnostic Thresholds for Central Blood Pressure Measurements Based on Long-Term Cardiovascular Risks

Journal of the American College of Cardiology, 2013-11, Vol.62 (19), p.1780-1787

2013

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Dual Activation of Phosphodiesterase 3 and 4 Regulates Basal Cardiac Pacemaker Function and Beyond

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8414

2021

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Synergism of coupled subsarcolemmal Ca2+ clocks and sarcolemmal voltage clocks confers robust and flexible pacemaker function in a novel pacemaker cell model

American journal of physiology. Heart and circulatory physiology, 2009-03, Vol.296 (3), p.H594-H615

2009

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Pulse Wave Velocity Is an Independent Predictor of the Longitudinal Increase in Systolic Blood Pressure and of Incident Hypertension in the Baltimore Longitudinal Study of Aging

Journal of the American College of Cardiology, 2008-04, Vol.51 (14), p.1377-1383

2008

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Pharmacological Strategies to Retard Cardiovascular Aging

Circulation research, 2016-05, Vol.118 (10), p.1626-1642

2016

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So! What's aging? Is cardiovascular aging a disease?

Journal of molecular and cellular cardiology, 2015-06, Vol.83, p.1-13

Lakatta, Edward G

2015

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Metabolic syndrome across Europe: Different clusters of risk factors

European journal of preventive cardiology, 2015-04, Vol.22 (4), p.486-491

2015

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Positive Feedback Mechanisms among Local Ca Releases, NCX, and ICaL Ignite Pacemaker Action Potentials

Biophysical journal, 2018-03, Vol.114 (5), p.1176-1189

2018

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Calpain-1 Regulation of Matrix Metalloproteinase 2 Activity in Vascular Smooth Muscle Cells Facilitates Age-Associated Aortic Wall Calcification and Fibrosis

Hypertension (Dallas, Tex. 1979), 2012-11, Vol.60 (5), p.1192-1199

2012

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The reality of aging viewed from the arterial wall

Artery research, 2013-06, Vol.7 (2), p.73-80

Lakatta, Edward G

2013

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Longitudinal Perspective on the Conundrum of Central Arterial Stiffness, Blood Pressure, and Aging

Hypertension (Dallas, Tex. 1979), 2014-12, Vol.64 (6), p.1219-1227

2014

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Mechanisms of Beat-to-Beat Regulation of Cardiac Pacemaker Cell Function by Ca2+ Cycling Dynamics

Biophysical journal, 2013-10, Vol.105 (7), p.1551-1561

2013

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Modern concepts concerning the origin of the heartbeat

Physiology (Bethesda, Md.), 2013-03, Vol.28 (2), p.74-92

2013

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Metformin Attenuates Hyperglycaemia-Stimulated Pro-Fibrotic Gene Expression in Adventitial Fibroblasts via Inhibition of Discoidin Domain Receptor 2

International journal of molecular sciences, 2022-12, Vol.24 (1), p.585

2022

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Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults

Circulation (New York, N.Y.), 2005-06, Vol.111 (25), p.3384-3390

2005

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To help aging populations, classify organismal senescence

Science (American Association for the Advancement of Science), 2019-11, Vol.366 (6465), p.576-578

2019

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A Coupled SYSTEM of Intracellular Ca2+ Clocks and Surface Membrane Voltage Clocks Controls the Timekeeping Mechanism of the Heartʼs Pacemaker

Matrix Metalloproteinases Promote Arterial Remodeling in Aging, Hypertension, and Atherosclerosis

What keeps us ticking: a funny current, a calcium clock, or both?

The Conundrum of Arterial Stiffness, Elevated Blood Pressure, and Aging

Increased Drp1 Acetylation by Lipid Overload Induces Cardiomyocyte Death and Heart Dysfunction

Resveratrol Prevents High Fat/Sucrose Diet-Induced Central Arterial Wall Inflammation and Stiffening in Nonhuman Primates

Role of inflammation in the pathogenesis of arterial stiffness

Aging-Associated Cardiovascular Changes and Their Relationship to Heart Failure

Biophysical Characterization of the Underappreciated and Important Relationship Between Heart Rate Variability and Heart Rate

Derivation and Validation of Diagnostic Thresholds for Central Blood Pressure Measurements Based on Long-Term Cardiovascular Risks

Dual Activation of Phosphodiesterase 3 and 4 Regulates Basal Cardiac Pacemaker Function and Beyond

Synergism of coupled subsarcolemmal Ca2+ clocks and sarcolemmal voltage clocks confers robust and flexible pacemaker function in a novel pacemaker cell model

Pulse Wave Velocity Is an Independent Predictor of the Longitudinal Increase in Systolic Blood Pressure and of Incident Hypertension in the Baltimore Longitudinal Study of Aging

Pharmacological Strategies to Retard Cardiovascular Aging

So! What's aging? Is cardiovascular aging a disease?

Metabolic syndrome across Europe: Different clusters of risk factors

Positive Feedback Mechanisms among Local Ca Releases, NCX, and ICaL Ignite Pacemaker Action Potentials

Calpain-1 Regulation of Matrix Metalloproteinase 2 Activity in Vascular Smooth Muscle Cells Facilitates Age-Associated Aortic Wall Calcification and Fibrosis

The reality of aging viewed from the arterial wall

Longitudinal Perspective on the Conundrum of Central Arterial Stiffness, Blood Pressure, and Aging

Mechanisms of Beat-to-Beat Regulation of Cardiac Pacemaker Cell Function by Ca2+ Cycling Dynamics

Modern concepts concerning the origin of the heartbeat

Metformin Attenuates Hyperglycaemia-Stimulated Pro-Fibrotic Gene Expression in Adventitial Fibroblasts via Inhibition of Discoidin Domain Receptor 2

Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults

To help aging populations, classify organismal senescence

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