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Biopanning and rapid analysis of selective interactive ligands

Nature medicine, 2001-11, Vol.7 (11), p.1249-1253

2001

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Model‐Based Design of a Decision Tree for Treating HER2+ Cancers Based on Genetic and Protein Biomarkers

CPT: pharmacometrics and systems pharmacology, 2015-03, Vol.4 (3), p.212-220

2015

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An Anti-Angiogenic State in Mice and Humans with Retinal Photoreceptor Cell Degeneration

Proceedings of the National Academy of Sciences - PNAS, 2001-08, Vol.98 (18), p.10368-10373

2001

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Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands

Cancer cell, 2004-09, Vol.6 (3), p.275-284

2004

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398 - The oligoclonal anti-EGFR antibody MM-151 synergizes with trametinib in KRAS wildtype and mutant colorectal cancer models resistant to conventional monoclonal anti-EGFR antibodies

European journal of cancer (1990), 2016-12, Vol.69, p.S131-S131

2016

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Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis

Cancer research (Chicago, Ill.), 2000-02, Vol.60 (3), p.722-727

2000

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CD13/APN is activated by angiogenic signals and is essential for capillary tube formation

Blood, 2001-02, Vol.97 (3), p.652-659

2001

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Aminopeptidase A is a functional target in angiogenic blood vessels

Cancer cell, 2004-02, Vol.5 (2), p.151-162

2004

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Treatment of hypoxia-induced retinopathy with targeted proapoptotic peptidomimetic in a mouse model of disease

The FASEB journal, 2007-10, Vol.21 (12), p.3272-3278

2007

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Identification of Receptor Ligands with Phage Display Peptide Libraries

The Journal of nuclear medicine (1978), 1999-05, Vol.40 (5), p.883-888

1999

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Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries

Cancer research (Chicago, Ill.), 2006, Vol.66 (1), p.34-40

2006

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Integrin-binding peptides derived from phage display libraries

Methods in molecular biology (Clifton, N.J.), 1999, Vol.129, p.3

1999

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Abstract B1-57: HER2+ cancer dependence on PI3K vs. MAPK signaling pathways is predicted by expression of 3 protein biomarkers, and informs optimal combination treatment strategies

Cancer research (Chicago, Ill.), 2015-11, Vol.75 (22_Supplement_2), p.B1-B1-57

2015

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Measurement of interstitial fluid pressure (IFP) and circulating biomarkers in soft tissue sarcoma (STS): An exploratory phase II clinical and correlative study of sorafenib (SOR) in patients with refractory STS (NCI Protocol 6948)

Journal of clinical oncology, 2010-05, Vol.28 (15_suppl), p.10091-10091

2010

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Abstract P3-14-09: Preclinical Safety and Activity of MM-302, a HER2-Targeted Liposomal Doxorubicin Designed To Have an Improved Safety and Efficacy Profile over Approved Anthracyclines

Cancer research (Chicago, Ill.), 2010-12, Vol.70 (24_Supplement), p.P3-P3-14-09

2010

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SEM1, a homologue of the split hand/split foot malformation candidate gene Dss1, regulates exocytosis and pseudohyphal differentiation in yeast

Proceedings of the National Academy of Sciences - PNAS, 1999-02, Vol.96 (3), p.909-914

1999

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Model of Unidirectional Transluminal Gene Transfer

Molecular therapy, 2004-02, Vol.9 (2), p.305-310

2004

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Efficacy, Safety, and Biomarkers of Neoadjuvant Bevacizumab, Radiation Therapy, and Fluorouracil in Rectal Cancer: A Multidisciplinary Phase II Study

Journal of clinical oncology, 2009-06, Vol.27 (18), p.3020-3026

2009

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Targeted Induction of Lung Endothelial Cell Apoptosis Causes Emphysema-like Changes in the Mouse

The Journal of biological chemistry, 2008-10, Vol.283 (43), p.29447-29460

2008

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BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors

Molecular cancer therapeutics, 2022-12, Vol.21 (12), p.1747-1756

2022

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Abstract 1724: Microinjection of Nectin-4/CD137 tumor-targeted immune cell agonist (TICA™) activates the local tumor microenvironment

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1724-1724

2021

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Comprehensive Surfaceome Profiling to Identify and Validate Novel Cell-Surface Targets in Osteosarcoma

Molecular cancer therapeutics, 2022-06, Vol.21 (6), p.903-913

2022

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Effects of sorafenib on intra-tumoral interstitial fluid pressure and circulating biomarkers in patients with refractory sarcomas (NCI protocol 6948)

PloS one, 2012-02, Vol.7 (2), p.e26331-e26331

2012

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Abstract LB008: Integrative surfaceome profiling identifies immunotherapeutic targets in osteosarcomas (OS); Preclinical testing of BT1769, an MT1-MMP-targeted Bicycle Toxin Conjugate, in OS by the Pediatric Preclinical Testing Consortium (PPTC)

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.LB008-LB008

2021

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Abstract 1826: In vivo evaluation of NK-TICA®, a novel Bicycle® tumor-targeted immune cell agonist (TICA) designed to engage NK cells

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.1826-1826

2023

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Biopanning and rapid analysis of selective interactive ligands

Model‐Based Design of a Decision Tree for Treating HER2+ Cancers Based on Genetic and Protein Biomarkers

An Anti-Angiogenic State in Mice and Humans with Retinal Photoreceptor Cell Degeneration

Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands

398 - The oligoclonal anti-EGFR antibody MM-151 synergizes with trametinib in KRAS wildtype and mutant colorectal cancer models resistant to conventional monoclonal anti-EGFR antibodies

Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis

CD13/APN is activated by angiogenic signals and is essential for capillary tube formation

Aminopeptidase A is a functional target in angiogenic blood vessels

Treatment of hypoxia-induced retinopathy with targeted proapoptotic peptidomimetic in a mouse model of disease

Identification of Receptor Ligands with Phage Display Peptide Libraries

Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries

Integrin-binding peptides derived from phage display libraries

Abstract B1-57: HER2+ cancer dependence on PI3K vs. MAPK signaling pathways is predicted by expression of 3 protein biomarkers, and informs optimal combination treatment strategies

Measurement of interstitial fluid pressure (IFP) and circulating biomarkers in soft tissue sarcoma (STS): An exploratory phase II clinical and correlative study of sorafenib (SOR) in patients with refractory STS (NCI Protocol 6948)

Abstract P3-14-09: Preclinical Safety and Activity of MM-302, a HER2-Targeted Liposomal Doxorubicin Designed To Have an Improved Safety and Efficacy Profile over Approved Anthracyclines

SEM1, a homologue of the split hand/split foot malformation candidate gene Dss1, regulates exocytosis and pseudohyphal differentiation in yeast

Model of Unidirectional Transluminal Gene Transfer

Efficacy, Safety, and Biomarkers of Neoadjuvant Bevacizumab, Radiation Therapy, and Fluorouracil in Rectal Cancer: A Multidisciplinary Phase II Study

Targeted Induction of Lung Endothelial Cell Apoptosis Causes Emphysema-like Changes in the Mouse

BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors

Abstract 1724: Microinjection of Nectin-4/CD137 tumor-targeted immune cell agonist (TICA™) activates the local tumor microenvironment

Comprehensive Surfaceome Profiling to Identify and Validate Novel Cell-Surface Targets in Osteosarcoma

Effects of sorafenib on intra-tumoral interstitial fluid pressure and circulating biomarkers in patients with refractory sarcomas (NCI protocol 6948)

Abstract LB008: Integrative surfaceome profiling identifies immunotherapeutic targets in osteosarcomas (OS); Preclinical testing of BT1769, an MT1-MMP-targeted Bicycle Toxin Conjugate, in OS by the Pediatric Preclinical Testing Consortium (PPTC)

Abstract 1826: In vivo evaluation of NK-TICA®, a novel Bicycle® tumor-targeted immune cell agonist (TICA) designed to engage NK cells

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