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Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

Nature medicine, 2003-02, Vol.9 (2), p.213-219

2003

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Direct and Indirect Mechanisms for Regulation of Fatty Acid Synthase Gene Expression by Liver X Receptors

The Journal of biological chemistry, 2002-03, Vol.277 (13), p.11019-11025

2002

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LXRs Control Lipid-Inducible Expression of the Apolipoprotein E Gene in Macrophages and Adipocytes

Proceedings of the National Academy of Sciences - PNAS, 2001-01, Vol.98 (2), p.507-512

2001

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Liver X receptor modulators: a review of recently patented compounds (2009 - 2012)

Expert opinion on therapeutic patents, 2013-10, Vol.23 (10), p.1317-1335

2013

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Synthetic LXR Ligand Inhibits the Development of Atherosclerosis in Mice

Proceedings of the National Academy of Sciences - PNAS, 2002-05, Vol.99 (11), p.7604-7609

2002

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Activation of Liver X Receptor Improves Glucose Tolerance through Coordinate Regulation of Glucose Metabolism in Liver and Adipose Tissue

Proceedings of the National Academy of Sciences - PNAS, 2003-04, Vol.100 (9), p.5419-5424

2003

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Identification of Macrophage Liver X Receptors as Inhibitors of Atherosclerosis

Proceedings of the National Academy of Sciences - PNAS, 2002-09, Vol.99 (18), p.11896-11901

2002

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Farnesoid X-Activated Receptor Induces Apolipoprotein C-II Transcription: a Molecular Mechanism Linking Plasma Triglyceride Levels to Bile Acids

Molecular endocrinology (Baltimore, Md.), 2001-10, Vol.15 (10), p.1720-1728

2001

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Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (11), p.4337-4342

2009

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The Phospholipid Transfer Protein Gene Is a Liver X Receptor Target Expressed by Macrophages in Atherosclerotic Lesions

Molecular and Cellular Biology, 2003-03, Vol.23 (6), p.2182-2191

2003

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Small-Molecule Inducer of β Cell Proliferation Identified by High-Throughput Screening

Journal of the American Chemical Society, 2013-02, Vol.135 (5), p.1669-1672

2013

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Control of Cellular Cholesterol Efflux by the Nuclear Oxysterol Receptor LXRα

Proceedings of the National Academy of Sciences - PNAS, 2000-10, Vol.97 (22), p.12097-12102

2000

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Autoregulation of the Human Liver X Receptor α Promoter

Molecular and Cellular Biology, 2001-11, Vol.21 (22), p.7558-7568

2001

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Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta

The Journal of biological chemistry, 2002-08, Vol.277 (35), p.31900-31908

2002

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Identification of the DNA Binding Specificity and Potential Target Genes for the Farnesoid X-activated Receptor

The Journal of biological chemistry, 2000-04, Vol.275 (14), p.10638-10647

2000

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Liver X receptors are regulators of adipocyte gene expression but not differentiation: identification of apoD as a direct target

Journal of lipid research, 2004-04, Vol.45 (4), p.616-625

2004

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Structure-Guided Design of N-Phenyl Tertiary Amines as Transrepression-Selective Liver X Receptor Modulators with Anti-Inflammatory Activity

Journal of medicinal chemistry, 2008-09, Vol.51 (18), p.5758-5765

2008

Volltextzugriff (PDF)

Correction to “Small-Molecule Inducer of β Cell Proliferation Identified by High-Throughput Screening”

Journal of the American Chemical Society, 2013-03, Vol.135 (11), p.4573-4573

2013

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Orphan nuclear receptors find a home in the arterial wall

Current atherosclerosis reports, 2002-05, Vol.4 (3), p.213-221

2002

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An Absorbing Study of Cholesterol

Science (American Association for the Advancement of Science), 2000-12, Vol.290 (5497), p.1709-1711

2000

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A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis

Molecular cell, 2001, Vol.7 (1), p.161-171

2001

Volltextzugriff (PDF)

Liver X receptors are regulators of adipocyte gene expression but not differentiation

Journal of lipid research, 2004-04, Vol.45 (4), p.616-625

2004

Volltextzugriff (PDF)

Regulated Expression of the Apolipoprotein E/C-I/C-IV/C-II Gene Cluster in Murine and Human Macrophages

The Journal of biological chemistry, 2002-08, Vol.277 (35), p.31900-31908

2002

Volltextzugriff (PDF)

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRalpha

Proceedings of the National Academy of Sciences - PNAS, 2000-10, Vol.97 (22), p.12097

2000

Volltextzugriff (PDF)

Characterization of the farnesoid -X -activated receptor: Identification of the DNA binding site, target genes and transcriptional coactivator proteins

Laffitte, Bryan A

2000

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Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

Direct and Indirect Mechanisms for Regulation of Fatty Acid Synthase Gene Expression by Liver X Receptors

LXRs Control Lipid-Inducible Expression of the Apolipoprotein E Gene in Macrophages and Adipocytes

Liver X receptor modulators: a review of recently patented compounds (2009 - 2012)

Synthetic LXR Ligand Inhibits the Development of Atherosclerosis in Mice

Activation of Liver X Receptor Improves Glucose Tolerance through Coordinate Regulation of Glucose Metabolism in Liver and Adipose Tissue

Identification of Macrophage Liver X Receptors as Inhibitors of Atherosclerosis

Farnesoid X-Activated Receptor Induces Apolipoprotein C-II Transcription: a Molecular Mechanism Linking Plasma Triglyceride Levels to Bile Acids

Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids

The Phospholipid Transfer Protein Gene Is a Liver X Receptor Target Expressed by Macrophages in Atherosclerotic Lesions

Small-Molecule Inducer of β Cell Proliferation Identified by High-Throughput Screening

Control of Cellular Cholesterol Efflux by the Nuclear Oxysterol Receptor LXRα

Autoregulation of the Human Liver X Receptor α Promoter

Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta

Identification of the DNA Binding Specificity and Potential Target Genes for the Farnesoid X-activated Receptor

Liver X receptors are regulators of adipocyte gene expression but not differentiation: identification of apoD as a direct target

Structure-Guided Design of N-Phenyl Tertiary Amines as Transrepression-Selective Liver X Receptor Modulators with Anti-Inflammatory Activity

Correction to “Small-Molecule Inducer of β Cell Proliferation Identified by High-Throughput Screening”

Orphan nuclear receptors find a home in the arterial wall

An Absorbing Study of Cholesterol

A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis

Liver X receptors are regulators of adipocyte gene expression but not differentiation

Regulated Expression of the Apolipoprotein E/C-I/C-IV/C-II Gene Cluster in Murine and Human Macrophages

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXRalpha

Characterization of the farnesoid -X -activated receptor: Identification of the DNA binding site, target genes and transcriptional coactivator proteins

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