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Makrophagen in der Krankheitsentstehung und Therapie

Biospektrum, 2021-03, Vol.27 (2), p.149-151

Lachmann, Nico

2021

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From macrophage biology to macrophage-based cellular immunotherapies

Gene therapy, 2021-09, Vol.28 (9), p.473-476

2021

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Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections

Nature communications, 2018-11, Vol.9 (1), p.5088-13, Article 5088

2018

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Alveolar macrophages in tissue homeostasis, inflammation, and infection: evolving concepts of therapeutic targeting

The Journal of clinical investigation, 2023-10, Vol.133 (19), p.1-12

2023

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Beyond "Big Eaters": The Versatile Role of Alveolar Macrophages in Health and Disease

International journal of molecular sciences, 2021-03, Vol.22 (7), p.3308

2021

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Continuous human iPSC-macrophage mass production by suspension culture in stirred tank bioreactors

Nature protocols, 2022-02, Vol.17 (2), p.513-539

2022

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In vitro systems to study inborn errors of immunity using human induced pluripotent stem cells

Frontiers in immunology, 2022-11, Vol.13, p.1024935-1024935

2022

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Lost in translation: pluripotent stem cell‐derived hematopoiesis

EMBO molecular medicine, 2015-11, Vol.7 (11), p.1388-1402

2015

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Pulmonary Transplantation of Human Induced Pluripotent Stem Cell-derived Macrophages Ameliorates Pulmonary Alveolar Proteinosis

American journal of respiratory and critical care medicine, 2018-08, Vol.198 (3), p.350-360

2018

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New Drugs for an Old Foe: Mycobacterium tuberculosis Meets PSC-Derived Macrophages

Stem cell reports, 2019-12, Vol.13 (6), p.957-959

2019

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TALEN-mediated functional correction of human iPSC-derived macrophages in context of hereditary pulmonary alveolar proteinosis

Scientific reports, 2017-11, Vol.7 (1), p.15195-11, Article 15195

2017

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Lentiviral gene therapy and vitamin B3 treatment enable granulocytic differentiation of G6PC3-deficient induced pluripotent stem cells

Gene therapy, 2020-06, Vol.27 (6), p.297-306

2020

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A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells

Nucleic acids research, 2015-02, Vol.43 (3), p.1577

2015

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Analysis of CFTR mRNA and Protein in Peripheral Blood Mononuclear Cells via Quantitative Real-Time PCR and Western Blot

International journal of molecular sciences, 2024-06, Vol.25 (12), p.6367

2024

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Long-Term Safety and Efficacy of Gene-Pulmonary Macrophage Transplantation Therapy of PAP in Csf2ra−/− Mice

Molecular therapy, 2019-09, Vol.27 (9), p.1597-1611

2019

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Large-Scale Hematopoietic Differentiation of Human Induced Pluripotent Stem Cells Provides Granulocytes or Macrophages for Cell Replacement Therapies

Stem cell reports, 2015-02, Vol.4 (2), p.282-296

2015

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Viral modulation of type II interferon increases T cell adhesion and virus spread

Nature communications, 2024-06, Vol.15 (1), p.5318-18, Article 5318

2024

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CARs and beyond: tailoring macrophage-based cell therapeutics to combat solid malignancies

Journal for immunotherapy of cancer, 2021-08, Vol.9 (8), p.e002741

2021

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Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis

Science translational medicine, 2014-08, Vol.6 (250), p.250ra113

2014

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Myeloid cell‐based delivery of IFN‐γ reprograms the leukemia microenvironment and induces anti‐tumoral immune responses

EMBO molecular medicine, 2021-10, Vol.13 (10), p.e13598-n/a

2021

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Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions

Molecular medicine (Cambridge, Mass.), 2016-01, Vol.22 (1), p.274-285

2016

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Pulmonary transplantation of alpha-1 antitrypsin (AAT)-transgenic macrophages provides a source of functional human AAT in vivo

Gene therapy, 2021-09, Vol.28 (9), p.477-493

2021

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A 3D iPSC-differentiation model identifies interleukin-3 as a regulator of early human hematopoietic specification

Haematologica (Roma), 2021-05, Vol.106 (5), p.1354

2021

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CAR macrophages tuning the immune symphony of anti-cancer therapies

Cell stem cell, 2024-06, Vol.31 (6), p.791-793

2024

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Generation of human induced pluripotent stem cell line MHHi029-A from a male Fabry disease patient carrying c.959A > T mutation

Stem cell research, 2024-06, Vol.77, p.103404, Article 103404

2024

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Makrophagen in der Krankheitsentstehung und Therapie

From macrophage biology to macrophage-based cellular immunotherapies

Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections

Alveolar macrophages in tissue homeostasis, inflammation, and infection: evolving concepts of therapeutic targeting

Beyond "Big Eaters": The Versatile Role of Alveolar Macrophages in Health and Disease

Continuous human iPSC-macrophage mass production by suspension culture in stirred tank bioreactors

In vitro systems to study inborn errors of immunity using human induced pluripotent stem cells

Lost in translation: pluripotent stem cell‐derived hematopoiesis

Pulmonary Transplantation of Human Induced Pluripotent Stem Cell-derived Macrophages Ameliorates Pulmonary Alveolar Proteinosis

New Drugs for an Old Foe: Mycobacterium tuberculosis Meets PSC-Derived Macrophages

TALEN-mediated functional correction of human iPSC-derived macrophages in context of hereditary pulmonary alveolar proteinosis

Lentiviral gene therapy and vitamin B3 treatment enable granulocytic differentiation of G6PC3-deficient induced pluripotent stem cells

A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells

Analysis of CFTR mRNA and Protein in Peripheral Blood Mononuclear Cells via Quantitative Real-Time PCR and Western Blot

Long-Term Safety and Efficacy of Gene-Pulmonary Macrophage Transplantation Therapy of PAP in Csf2ra−/− Mice

Large-Scale Hematopoietic Differentiation of Human Induced Pluripotent Stem Cells Provides Granulocytes or Macrophages for Cell Replacement Therapies

Viral modulation of type II interferon increases T cell adhesion and virus spread

CARs and beyond: tailoring macrophage-based cell therapeutics to combat solid malignancies

Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis

Myeloid cell‐based delivery of IFN‐γ reprograms the leukemia microenvironment and induces anti‐tumoral immune responses

Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions

Pulmonary transplantation of alpha-1 antitrypsin (AAT)-transgenic macrophages provides a source of functional human AAT in vivo

A 3D iPSC-differentiation model identifies interleukin-3 as a regulator of early human hematopoietic specification

CAR macrophages tuning the immune symphony of anti-cancer therapies

Generation of human induced pluripotent stem cell line MHHi029-A from a male Fabry disease patient carrying c.959A > T mutation

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