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Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (47), p.19408-19413

2012

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Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance

Proceedings of the National Academy of Sciences - PNAS, 2019-05, Vol.116 (19), p.9433-9442

2019

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Expression of the lncRNA Maternally Expressed Gene 3 (MEG3) Contributes to the Control of Lung Cancer Cell Proliferation by the Rb Pathway

PloS one, 2016-11, Vol.11 (11), p.e0166363-e0166363

2016

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Activation of KRAS Mediates Resistance to Targeted Therapy in MET Exon 14-mutant Non-small Cell Lung Cancer

Clinical cancer research, 2019-02, Vol.25 (4), p.1248-1260

2019

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Uncovering molecular features driving lung adenocarcinoma heterogeneity in patients who formerly smoked

Journal of translational medicine, 2024-07, Vol.22 (1), p.634-14, Article 634

2024

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Response to ERBB3-Directed Targeted Therapy in NRG1 -Rearranged Cancers

Cancer discovery, 2018-06, Vol.8 (6), p.686-695

2018

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New insights into the biology and development of lung cancer in never smokers—implications for early detection and treatment

Journal of translational medicine, 2023-08, Vol.21 (1), p.1-585, Article 585

2023

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Lung Cancer Cell Lines as Tools for Biomedical Discovery and Research

JNCI : Journal of the National Cancer Institute, 2010-09, Vol.102 (17), p.1310-1321

2010

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Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells

eLife, 2018-11, Vol.7

2018

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Lung Cancer Signatures in Plasma Based on Proteome Profiling of Mouse Tumor Models

Cancer cell, 2011-09, Vol.20 (3), p.289-299

2011

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Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma

eLife, 2015-06, Vol.4, p.e06907-e06907

2015

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Epithelial tumor suppressor ELF3 is a lineage-specific amplified oncogene in lung adenocarcinoma

Nature communications, 2019-11, Vol.10 (1), p.5438-13, Article 5438

2019

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PIK3CA Mutations and Copy Number Gains in Human Lung Cancers

Cancer research (Chicago, Ill.), 2008-09, Vol.68 (17), p.6913-6921

2008

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Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (39), p.16375-16380

2011

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Resistance to BET inhibitors in lung adenocarcinoma is mediated by casein kinase phosphorylation of BRD4

Oncogenesis (New York, NY), 2021-03, Vol.10 (3), p.27-27, Article 27

2021

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Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer

eLife, 2021-06, Vol.10

2021

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Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines

PloS one, 2009-02, Vol.4 (2), p.e4576-e4576

2009

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Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability

PloS one, 2012-03, Vol.7 (3), p.e33003-e33003

2012

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Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1

Proceedings of the National Academy of Sciences - PNAS, 2012-01, Vol.109 (3), p.E119-E126

2012

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Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells

Cell reports (Cambridge), 2022-02, Vol.38 (6), p.110343-110343, Article 110343

2022

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Delineating spatial cell-cell interactions in the solid tumour microenvironment through the lens of highly multiplexed imaging

Frontiers in immunology, 2023-10, Vol.14, p.1275890-1275890

2023

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Characterizing the secretome of EGFR mutant lung adenocarcinoma

Frontiers in oncology, 2024-01, Vol.13, p.1286821-1286821

2024

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Activation of GATA binding protein 6 (GATA6) sustains oncogenic lineage-survival in esophageal adenocarcinoma

Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (11), p.4251-4256

2012

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CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development

Oncoimmunology, 2022-01, Vol.11 (1), p.2010905-2010905

2022

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Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development

PloS one, 2012-05, Vol.7 (5), p.e37775

2012

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Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins

Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance

Expression of the lncRNA Maternally Expressed Gene 3 (MEG3) Contributes to the Control of Lung Cancer Cell Proliferation by the Rb Pathway

Activation of KRAS Mediates Resistance to Targeted Therapy in MET Exon 14-mutant Non-small Cell Lung Cancer

Uncovering molecular features driving lung adenocarcinoma heterogeneity in patients who formerly smoked

Response to ERBB3-Directed Targeted Therapy in NRG1 -Rearranged Cancers

New insights into the biology and development of lung cancer in never smokers—implications for early detection and treatment

Lung Cancer Cell Lines as Tools for Biomedical Discovery and Research

Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells

Lung Cancer Signatures in Plasma Based on Proteome Profiling of Mouse Tumor Models

Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma

Epithelial tumor suppressor ELF3 is a lineage-specific amplified oncogene in lung adenocarcinoma

PIK3CA Mutations and Copy Number Gains in Human Lung Cancers

Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines

Resistance to BET inhibitors in lung adenocarcinoma is mediated by casein kinase phosphorylation of BRD4

Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer

Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines

Lung adenocarcinoma of never smokers and smokers harbor differential regions of genetic alteration and exhibit different levels of genomic instability

Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1

Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells

Delineating spatial cell-cell interactions in the solid tumour microenvironment through the lens of highly multiplexed imaging

Characterizing the secretome of EGFR mutant lung adenocarcinoma

Activation of GATA binding protein 6 (GATA6) sustains oncogenic lineage-survival in esophageal adenocarcinoma

CCL5 production in lung cancer cells leads to an altered immune microenvironment and promotes tumor development

Divergent genomic and epigenomic landscapes of lung cancer subtypes underscore the selection of different oncogenic pathways during tumor development

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