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Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology

Current Alzheimer research, 2016-01, Vol.13 (1), p.18

2016

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Microbiota in neuroinflammation and synaptic dysfunction: a focus on Alzheimer's disease

Molecular neurodegeneration, 2022-03, Vol.17 (1), p.19-19, Article 19

2022

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Complement and microglia mediate early synapse loss in Alzheimer mouse models

Science (American Association for the Advancement of Science), 2016-05, Vol.352 (6286), p.712-716

2016

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The epigenetics of aging and neurodegeneration

Progress in neurobiology, 2015-08, Vol.131, p.21-64

2015

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De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease

Human molecular genetics, 2013-08, Vol.22 (15), p.3077-3092

2013

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Passive Aβ Immunotherapy: Current Achievements and Future Perspectives

Molecules (Basel, Switzerland), 2018-05, Vol.23 (5), p.1068

2018

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Galactic cosmic radiation leads to cognitive impairment and increased aβ plaque accumulation in a mouse model of Alzheimer's disease

PloS one, 2012-12, Vol.7 (12), p.e53275

2012

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The Importance of Complement-Mediated Immune Signaling in Alzheimer's Disease Pathogenesis

International journal of molecular sciences, 2024-01, Vol.25 (2), p.817

2024

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Temporal Characterization of the Amyloidogenic APPswe/PS1dE9;hAPOE4 Mouse Model of Alzheimer’s Disease

International journal of molecular sciences, 2024-06, Vol.25 (11), p.5754

2024

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Phosphorylated Aβ peptides in human Down syndrome brain and different Alzheimer's-like mouse models

Acta neuropathologica communications, 2020-07, Vol.8 (1), p.118-14, Article 118

2020

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Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease

Alzheimer's research & therapy, 2011-01, Vol.3 (1), p.1-1

2011

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Development of the clinical candidate PBD-C06, a humanized pGlu3-Aβ-specific antibody against Alzheimer's disease with reduced complement activation

Scientific reports, 2020-02, Vol.10 (1), p.3294-13, Article 3294

2020

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Combination of the Glutaminyl Cyclase Inhibitor PQ912 (Varoglutamstat) and the Murine Monoclonal Antibody PBD-C06 (m6) Shows Additive Effects on Brain Aβ Pathology in Transgenic Mice

International journal of molecular sciences, 2021-10, Vol.22 (21), p.11791

2021

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Anti-Aβ antibodies incapable of reducing cerebral Aβ oligomers fail to attenuate spatial reference memory deficits in J20 mice

Neurobiology of disease, 2015-10, Vol.82, p.372-384

2015

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High-Energy, Whole-Body Proton Irradiation Differentially Alters Long-Term Brain Pathology and Behavior Dependent on Sex and Alzheimer's Disease Mutations

International journal of molecular sciences, 2023-02, Vol.24 (4), p.3615

2023

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Immunotherapy for Alzheimer's disease: hoops and hurdles

Molecular neurodegeneration, 2013-10, Vol.8 (1), p.36-36

Lemere, Cynthia A

2013

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Acute Effects of Focused Ultrasound-Induced Blood-Brain Barrier Opening on Anti-Pyroglu3 Abeta Antibody Delivery and Immune Responses

Biomolecules (Basel, Switzerland), 2022-07, Vol.12 (7), p.951

2022

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Can Alzheimer disease be prevented by amyloid-beta immunotherapy?

Nature reviews. Neurology, 2010-02, Vol.6 (2), p.108

2010

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Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Aβ assembly forms throughout life

Neurobiology of disease, 2009-11, Vol.36 (2), p.293-302

2009

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Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice

Science translational medicine, 2017-05, Vol.9 (392)

2017

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APP Processing Is Regulated by Cytoplasmic Phosphorylation

The Journal of cell biology, 2003-10, Vol.163 (1), p.83-95

2003

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Long-Term Sex- and Genotype-Specific Effects of 56Fe Irradiation on Wild-Type and APPswe/PS1dE9 Transgenic Mice

International journal of molecular sciences, 2021-12, Vol.22 (24), p.13305

2021

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Effector function of anti-pyroglutamate-3 Aβ antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer's-like mice

Alzheimer's research & therapy, 2020-01, Vol.12 (1), p.12-12, Article 12

2020

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Regional distribution of TDP-43 inclusions in Alzheimer disease (AD) brains: Their relation to AD common pathology

Neuropathology, 2009-10, Vol.29 (5), p.566-573

2009

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l-3- n-Butylphthalide ameliorates β-amyloid-induced neuronal toxicity in cultured neuronal cells

Neuroscience letters, 2008-03, Vol.434 (2), p.224-229

2008

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Aging in Down Syndrome and the Development of Alzheimer's Disease Neuropathology

Microbiota in neuroinflammation and synaptic dysfunction: a focus on Alzheimer's disease

Complement and microglia mediate early synapse loss in Alzheimer mouse models

The epigenetics of aging and neurodegeneration

De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease

Passive Aβ Immunotherapy: Current Achievements and Future Perspectives

Galactic cosmic radiation leads to cognitive impairment and increased aβ plaque accumulation in a mouse model of Alzheimer's disease

The Importance of Complement-Mediated Immune Signaling in Alzheimer's Disease Pathogenesis

Temporal Characterization of the Amyloidogenic APPswe/PS1dE9;hAPOE4 Mouse Model of Alzheimer’s Disease

Phosphorylated Aβ peptides in human Down syndrome brain and different Alzheimer's-like mouse models

Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease

Development of the clinical candidate PBD-C06, a humanized pGlu3-Aβ-specific antibody against Alzheimer's disease with reduced complement activation

Combination of the Glutaminyl Cyclase Inhibitor PQ912 (Varoglutamstat) and the Murine Monoclonal Antibody PBD-C06 (m6) Shows Additive Effects on Brain Aβ Pathology in Transgenic Mice

Anti-Aβ antibodies incapable of reducing cerebral Aβ oligomers fail to attenuate spatial reference memory deficits in J20 mice

High-Energy, Whole-Body Proton Irradiation Differentially Alters Long-Term Brain Pathology and Behavior Dependent on Sex and Alzheimer's Disease Mutations

Immunotherapy for Alzheimer's disease: hoops and hurdles

Acute Effects of Focused Ultrasound-Induced Blood-Brain Barrier Opening on Anti-Pyroglu3 Abeta Antibody Delivery and Immune Responses

Can Alzheimer disease be prevented by amyloid-beta immunotherapy?

Biochemical and immunohistochemical analysis of an Alzheimer's disease mouse model reveals the presence of multiple cerebral Aβ assembly forms throughout life

Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice

APP Processing Is Regulated by Cytoplasmic Phosphorylation

Long-Term Sex- and Genotype-Specific Effects of 56Fe Irradiation on Wild-Type and APPswe/PS1dE9 Transgenic Mice

Effector function of anti-pyroglutamate-3 Aβ antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer's-like mice

Regional distribution of TDP-43 inclusions in Alzheimer disease (AD) brains: Their relation to AD common pathology

l-3- n-Butylphthalide ameliorates β-amyloid-induced neuronal toxicity in cultured neuronal cells

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