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APC Mutations in Sporadic Colorectal Tumors: A Mutational "Hotspot" and Interdependence of the "Two Hits"

Proceedings of the National Academy of Sciences - PNAS, 2000-03, Vol.97 (7), p.3352-3357

2000

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Prognostic and Predictive Molecular Markers in Colorectal Carcinoma

Anticancer research, 2004-07, Vol.24 (4), p.2519-2530

2004

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Whole-Gene APC Deletions Cause Classical Familial Adenomatous Polyposis, but not Attenuated Polyposis or "Multiple" Colorectal Adenomas

Proceedings of the National Academy of Sciences - PNAS, 2002-03, Vol.99 (5), p.2954-2958

2002

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Analysis of Chromosomal Instability in Human Colorectal Adenomas with Two Mutational Hits at APC

Proceedings of the National Academy of Sciences - PNAS, 2002-12, Vol.99 (26), p.16910-16915

2002

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Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q

Human molecular genetics, 2000-09, Vol.9 (15), p.2215-2221

2000

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Comparison of CD44 expression in primary tumours and metastases of colorectal cancer

Oncology reports, 2006-10, Vol.16 (4), p.741-746

2006

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E-cadherin, CD44s and CD44v6 correlate with tumour differentiation in colorectal cancer

Oncology reports, 2005-05, Vol.13 (5), p.831

2005

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Thymidylate synthase and microsatellite instability in colorectal cancer: Implications for disease free survival, treatment response and survival with metastases

Acta oncologica, 2008, Vol.47 (6), p.1046-1053

2008

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Mismatch Repair Status Is a Predictive Factor of Tumour Response to 5-Fluorouracil and Irinotecan Chemotherapy in Patients with Advanced Colorectal Cancer

Tumor biology, 2007-01, Vol.28 (4), p.212-220

2007

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Thymidylate synthase expression levels: a prognostic and predictive role in advanced colorectal cancer

Oncology reports, 2005-09, Vol.14 (3), p.657

2005

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Low Collagenase-1 (MMP-1) and MT1-MMP Expression Levels Are Favourable Survival Markers in Advanced Colorectal Carcinoma

Oncology, 2003-01, Vol.65 (4), p.337-346

2003

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CD44 variant 6 expression predicts response to treatment in advanced colorectal cancer

Oncology reports, 2004-01, Vol.11 (1), p.41

2004

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Apoptotic Index and bcl-2 Expression as Prognostic Factors in Colorectal Carcinoma

Oncology, 2003-01, Vol.64 (4), p.435-442

2003

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Response to Chemotherapy (Irinotecan plus 5-Fluorouracil) in Colorectal Carcinoma Can Be Predicted by Tumour DNA Content

Oncology, 2004-01, Vol.66 (1), p.46-52

2004

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The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis

Nature medicine, 1999-09, Vol.5 (9), p.1071-1075

1999

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Mutation Cluster Region, Association Between Germline and Somatic Mutations and Genotype-Phenotype Correlation in Upper Gastrointestinal Familial Adenomatous Polyposis

The American journal of pathology, 2002-06, Vol.160 (6), p.2055-2061

2002

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APC Mutations Are Sufficient for the Growth of Early Colorectal Adenomas

Proceedings of the National Academy of Sciences - PNAS, 2000-02, Vol.97 (5), p.2225-2228

2000

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Refining the relation between 'first hits' and 'second hits' at the APC locus: the 'loose fit' model and evidence for differences in somatic mutation spectra among patients

Oncogene, 2003-07, Vol.22 (27), p.4257-4265

2003

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The androgen receptor exon 1 trinucleotide repeat does not act as a modifier of the age of presentation in breast cancer

European journal of cancer (1990), 2000-03, Vol.36 (4), p.533-534

2000

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The association of combined alpha and beta fibrinogen genotype on plasma fibrinogen levels in smokers and non-smokers

Journal of medical genetics, 1995-08, Vol.32 (8), p.585-589

1995

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Characterization of a dinucleotide repeat in the 92 kDa type IV collagenase gene (CLG4B), localization of CLG4B to chromosome 20 and the role of CLG4B in aortic aneurysmal disease

Annals of human genetics, 1995-01, Vol.59 (1), p.17-24

1995

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Nuclear Area is a Prognostic Determinant in Advanced Colorectal Cancer

Anticancer research, 2005-07, Vol.25 (4), p.3083-3088

2005

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Linkage disequilibrium across the fibrinogen locus as shown by five genetic polymorphisms, G/A −455 (HaeIII), C/T −148 (HindIII/AluI), T/G+1689 (AvaII), and BclI (β-fibrinogen) and TaqI (α-fibrinogen), and their detection by PCR

Human mutation, 1994, Vol.3 (1), p.79-81

1994

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APC Mutations in Sporadic Colorectal Tumors: A Mutational "Hotspot" and Interdependence of the "Two Hits"

Prognostic and Predictive Molecular Markers in Colorectal Carcinoma

Whole-Gene APC Deletions Cause Classical Familial Adenomatous Polyposis, but not Attenuated Polyposis or "Multiple" Colorectal Adenomas

Analysis of Chromosomal Instability in Human Colorectal Adenomas with Two Mutational Hits at APC

Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317Q

Comparison of CD44 expression in primary tumours and metastases of colorectal cancer

E-cadherin, CD44s and CD44v6 correlate with tumour differentiation in colorectal cancer

Thymidylate synthase and microsatellite instability in colorectal cancer: Implications for disease free survival, treatment response and survival with metastases

Mismatch Repair Status Is a Predictive Factor of Tumour Response to 5-Fluorouracil and Irinotecan Chemotherapy in Patients with Advanced Colorectal Cancer

Thymidylate synthase expression levels: a prognostic and predictive role in advanced colorectal cancer

Low Collagenase-1 (MMP-1) and MT1-MMP Expression Levels Are Favourable Survival Markers in Advanced Colorectal Carcinoma

CD44 variant 6 expression predicts response to treatment in advanced colorectal cancer

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

Apoptotic Index and bcl-2 Expression as Prognostic Factors in Colorectal Carcinoma

Response to Chemotherapy (Irinotecan plus 5-Fluorouracil) in Colorectal Carcinoma Can Be Predicted by Tumour DNA Content

The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis

Mutation Cluster Region, Association Between Germline and Somatic Mutations and Genotype-Phenotype Correlation in Upper Gastrointestinal Familial Adenomatous Polyposis

APC Mutations Are Sufficient for the Growth of Early Colorectal Adenomas

Refining the relation between 'first hits' and 'second hits' at the APC locus: the 'loose fit' model and evidence for differences in somatic mutation spectra among patients

Post-acute COVID-19 neuropsychiatric symptoms are not associated with ongoing nervous system injury

The androgen receptor exon 1 trinucleotide repeat does not act as a modifier of the age of presentation in breast cancer

The association of combined alpha and beta fibrinogen genotype on plasma fibrinogen levels in smokers and non-smokers

Characterization of a dinucleotide repeat in the 92 kDa type IV collagenase gene (CLG4B), localization of CLG4B to chromosome 20 and the role of CLG4B in aortic aneurysmal disease

Nuclear Area is a Prognostic Determinant in Advanced Colorectal Cancer

Linkage disequilibrium across the fibrinogen locus as shown by five genetic polymorphisms, G/A −455 (HaeIII), C/T −148 (HindIII/AluI), T/G+1689 (AvaII), and BclI (β-fibrinogen) and TaqI (α-fibrinogen), and their detection by PCR

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