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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

The New England journal of medicine, 2012-03, Vol.366 (10), p.883-892

2012

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Replication stress links structural and numerical cancer chromosomal instability

Nature (London), 2013-02, Vol.494 (7438), p.492-496

2013

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Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

Cell, 2017-11, Vol.171 (6), p.1259-1271.e11

2017

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Chromosomal Instability Confers Intrinsic Multidrug Resistance

Cancer research (Chicago, Ill.), 2011-03, Vol.71 (5), p.1858-1870

2011

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Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage

Annals of the rheumatic diseases, 2016-02, Vol.75 (2), p.449-458

2016

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Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts

PloS one, 2016-02, Vol.11 (2), p.e0148024-e0148024

2016

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Origins of lymphatic and distant metastases in human colorectal cancer

Science (American Association for the Advancement of Science), 2017-07, Vol.357 (6346), p.55-60

2017

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Ferulic acid: a key component in grass lignocellulose recalcitrance to hydrolysis

Plant biotechnology journal, 2015-12, Vol.13 (9), p.1224-1232

2015

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Macrophage migration and invasion is regulated by MMP10 expression

PloS one, 2013-05, Vol.8 (5), p.e63555

2013

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Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal

Cell, 2018-04, Vol.173 (3), p.611-623.e17

2018

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Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution

Cancer discovery, 2014-02, Vol.4 (2), p.175-185

2014

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Systems biology reveals how altered TGFβ signalling with age reduces protection against pro-inflammatory stimuli

PLoS computational biology, 2019-01, Vol.15 (1), p.e1006685-e1006685

2019

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Systematic Evaluation of the Prognostic Impact and Intratumour Heterogeneity of Clear Cell Renal Cell Carcinoma Biomarkers

European urology, 2014-11, Vol.66 (5), p.936-948

2014

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Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases

Annals of the rheumatic diseases, 2012-03, Vol.71 (3), p.455-462

2012

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Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology

Annals of the rheumatic diseases, 2016-11, Vol.75 (11), p.1989-1997

2016

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Cytokine-induced MMP13 Expression in Human Chondrocytes Is Dependent on Activating Transcription Factor 3 (ATF3) Regulation

The Journal of biological chemistry, 2017-02, Vol.292 (5), p.1625-1636

2017

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Novel Gain-of-Function Mutation in Stat1 Sumoylation Site Leads to CMC/CID Phenotype Responsive to Ruxolitinib

Journal of clinical immunology, 2019-11, Vol.39 (8), p.776-785

2019

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cAMP response element‐binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis

The FASEB journal, 2012-07, Vol.26 (7), p.3000-3011

2012

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Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy

Cancer discovery, 2015-08, Vol.5 (8), p.821-831

2015

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Gain‐of‐function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC)

European journal of immunology, 2015-10, Vol.45 (10), p.2834-2846

2015

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Serine proteinases in the turnover of the cartilage extracellular matrix in the joint: implications for therapeutics

British journal of pharmacology, 2019-01, Vol.176 (1), p.38-51

2019

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Matrix metalloproteinase‐13 is fully activated by neutrophil elastase and inactivates its serpin inhibitor, alpha‐1 antitrypsin: Implications for osteoarthritis

The FEBS journal, 2022-01, Vol.289 (1), p.121-139

2022

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Escape from nonsense-mediated decay associates with anti-tumor immunogenicity

Nature communications, 2020-07, Vol.11 (1), p.3800-11, Article 3800

2020

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

Replication stress links structural and numerical cancer chromosomal instability

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

Chromosomal Instability Confers Intrinsic Multidrug Resistance

Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage

Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts

Origins of lymphatic and distant metastases in human colorectal cancer

Ferulic acid: a key component in grass lignocellulose recalcitrance to hydrolysis

Macrophage migration and invasion is regulated by MMP10 expression

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal

Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution

Systems biology reveals how altered TGFβ signalling with age reduces protection against pro-inflammatory stimuli

Systematic Evaluation of the Prognostic Impact and Intratumour Heterogeneity of Clear Cell Renal Cell Carcinoma Biomarkers

Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases

BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer

Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology

Cytokine-induced MMP13 Expression in Human Chondrocytes Is Dependent on Activating Transcription Factor 3 (ATF3) Regulation

Novel Gain-of-Function Mutation in Stat1 Sumoylation Site Leads to CMC/CID Phenotype Responsive to Ruxolitinib

cAMP response element‐binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis

Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy

Gain‐of‐function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC)

Serine proteinases in the turnover of the cartilage extracellular matrix in the joint: implications for therapeutics

Matrix metalloproteinase‐13 is fully activated by neutrophil elastase and inactivates its serpin inhibitor, alpha‐1 antitrypsin: Implications for osteoarthritis

Escape from nonsense-mediated decay associates with anti-tumor immunogenicity

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