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Cardiac Microvascular Endothelial Enhancement of Cardiomyocyte Function Is Impaired by Inflammation and Restored by Empagliflozin

JACC. Basic to translational science, 2019-09, Vol.4 (5), p.575-591

2019

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Sex-specific cardiac remodeling in early and advanced stages of hypertrophic cardiomyopathy

PloS one, 2020-05, Vol.15 (5), p.e0232427-e0232427

2020

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Contribution of Impaired Parasympathetic Activity to Right Ventricular Dysfunction and Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension

Circulation (New York, N.Y.), 2018-02, Vol.137 (9), p.910-924

2018

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Hypertrophic Cardiomyopathy: A Vicious Cycle Triggered by Sarcomere Mutations and Secondary Disease Hits

Antioxidants & redox signaling, 2019-08, Vol.31 (4), p.318-358

2019

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β-adrenergic receptor signalling and its functional consequences in the diseased heart

European journal of clinical investigation, 2016-04, Vol.46 (4), p.362-374

2016

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Characterization of cardiac metabolism in iPSC-derived cardiomyocytes: lessons from maturation and disease modeling

Stem cell research & therapy, 2022-07, Vol.13 (1), p.1-332, Article 332

2022

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Translating myosin-binding protein C and titin abnormalities to whole-heart function using a novel calcium-contraction coupling model

Journal of molecular and cellular cardiology, 2024-05, Vol.190, p.13-23

2024

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Empagliflozin restores chronic kidney disease–induced impairment of endothelial regulation of cardiomyocyte relaxation and contraction

Kidney international, 2021-05, Vol.99 (5), p.1088-1101

2021

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Perturbed Length-Dependent Activation in Human Hypertrophic Cardiomyopathy With Missense Sarcomeric Gene Mutations

Circulation research, 2013-05, Vol.112 (11), p.1491-1505

2013

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Mitochondrial dysfunction in human hypertrophic cardiomyopathy is linked to cardiomyocyte architecture disruption and corrected by improving NADH-driven mitochondrial respiration

European heart journal, 2023-04, Vol.44 (13), p.1170-1185

2023

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The microtubule signature in cardiac disease: etiology, disease stage, and age dependency

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2023-10, Vol.193 (5), p.581-595

2023

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What grows together, goes together: assessing variability in cardiomyocyte function

The Journal of physiology, 2019-02, Vol.597 (3), p.665-666

Kuster, Diederik W. D.

2019

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The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes

Cardiovascular research, 2023-05, Vol.119 (5), p.1161-1174

2023

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Hypertrophic cardiomyopathy dysfunction mimicked in human engineered heart tissue and improved by sodium–glucose cotransporter 2 inhibitors

Cardiovascular research, 2024-03, Vol.120 (3), p.301-317

2024

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Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy

Circulation. Heart failure, 2021-01, Vol.14 (1), p.e007022-e007022

2021

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EGFR/IGF1R Signaling Modulates Relaxation in Hypertrophic Cardiomyopathy

Circulation research, 2023-08, Vol.133 (5), p.387-399

2023

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Single-cell transcriptomics provides insights into hypertrophic cardiomyopathy

Cell reports (Cambridge), 2022-05, Vol.39 (6), p.110809-110809, Article 110809

2022

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Characterization of heterozygous and homozygous mouse models with the most common hypertrophic cardiomyopathy mutation MYBPC3c.2373InsG in the Netherlands

Journal of molecular and cellular cardiology, 2023-12, Vol.185, p.65-76

2023

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DWORF Extends Life Span in a PLN-R14del Cardiomyopathy Mouse Model by Reducing Abnormal Sarcoplasmic Reticulum Clusters

Circulation research, 2023-12, Vol.133 (12), p.1006-1021

2023

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Mutation location of HCM-causing troponin T mutations defines the degree of myofilament dysfunction in human cardiomyocytes

Journal of molecular and cellular cardiology, 2021-01, Vol.150, p.77-90

2021

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MYBPC3's alternate ending: consequences and therapeutic implications of a highly prevalent 25 bp deletion mutation

Pflügers Archiv, 2014-02, Vol.466 (2), p.207-213

2014

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Sex Differences at the Time of Myectomy in Hypertrophic Cardiomyopathy

Circulation. Heart failure, 2018-06, Vol.11 (6), p.e004133-e004133

2018

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The Antibiotic Doxycycline Impairs Cardiac Mitochondrial and Contractile Function

International journal of molecular sciences, 2021-04, Vol.22 (8), p.4100

2021

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Real-Time Measurements of Calcium and Contractility Parameters in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Journal of visualized experiments, 2023-05 (195)

2023

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Altered C10 domain in cardiac myosin binding protein-C results in hypertrophic cardiomyopathy

Cardiovascular research, 2019-12, Vol.115 (14), p.1986-1997

2019

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Cardiac Microvascular Endothelial Enhancement of Cardiomyocyte Function Is Impaired by Inflammation and Restored by Empagliflozin

Sex-specific cardiac remodeling in early and advanced stages of hypertrophic cardiomyopathy

Contribution of Impaired Parasympathetic Activity to Right Ventricular Dysfunction and Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension

Hypertrophic Cardiomyopathy: A Vicious Cycle Triggered by Sarcomere Mutations and Secondary Disease Hits

β-adrenergic receptor signalling and its functional consequences in the diseased heart

Characterization of cardiac metabolism in iPSC-derived cardiomyocytes: lessons from maturation and disease modeling

Translating myosin-binding protein C and titin abnormalities to whole-heart function using a novel calcium-contraction coupling model

Empagliflozin restores chronic kidney disease–induced impairment of endothelial regulation of cardiomyocyte relaxation and contraction

Perturbed Length-Dependent Activation in Human Hypertrophic Cardiomyopathy With Missense Sarcomeric Gene Mutations

Mitochondrial dysfunction in human hypertrophic cardiomyopathy is linked to cardiomyocyte architecture disruption and corrected by improving NADH-driven mitochondrial respiration

The microtubule signature in cardiac disease: etiology, disease stage, and age dependency

What grows together, goes together: assessing variability in cardiomyocyte function

The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes

Hypertrophic cardiomyopathy dysfunction mimicked in human engineered heart tissue and improved by sodium–glucose cotransporter 2 inhibitors

Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy

EGFR/IGF1R Signaling Modulates Relaxation in Hypertrophic Cardiomyopathy

Single-cell transcriptomics provides insights into hypertrophic cardiomyopathy

Characterization of heterozygous and homozygous mouse models with the most common hypertrophic cardiomyopathy mutation MYBPC3c.2373InsG in the Netherlands

DWORF Extends Life Span in a PLN-R14del Cardiomyopathy Mouse Model by Reducing Abnormal Sarcoplasmic Reticulum Clusters

Mutation location of HCM-causing troponin T mutations defines the degree of myofilament dysfunction in human cardiomyocytes

MYBPC3's alternate ending: consequences and therapeutic implications of a highly prevalent 25 bp deletion mutation

Sex Differences at the Time of Myectomy in Hypertrophic Cardiomyopathy

The Antibiotic Doxycycline Impairs Cardiac Mitochondrial and Contractile Function

Real-Time Measurements of Calcium and Contractility Parameters in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Altered C10 domain in cardiac myosin binding protein-C results in hypertrophic cardiomyopathy

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