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Structure, function and pharmacology of human itch GPCRs

Nature (London), 2021-12, Vol.600 (7887), p.170-175

2021

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Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65

Nature (London), 2015-11, Vol.527 (7579), p.477-483

2015

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Discovery and Characterization of Novel GPR39 Agonists Allosterically Modulated by Zinc

Molecular pharmacology, 2016-12, Vol.90 (6), p.726-737

2016

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Biased signaling of the proton‐sensing receptor OGR1 by benzodiazepines

The FASEB journal, 2018-02, Vol.32 (2), p.862-874

2018

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Antagonist functional selectivity: 5-HT2A serotonin receptor antagonists differentially regulate 5-HT2A receptor protein level in vivo

The Journal of pharmacology and experimental therapeutics, 2011-10, Vol.339 (1), p.99

2011

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The Human Polyomavirus, JCV, Uses Serotonin Receptors to Infect Cells

Science (American Association for the Advancement of Science), 2004-11, Vol.306 (5700), p.1380-1383

2004

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Tuning up the right signal: chemical and genetic approaches to study GPCR functions

Current opinion in cell biology, 2014-04, Vol.27, p.51-55

2014

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Quantitative analysis of focused a-to-I RNA editing sites by ultra-high-throughput sequencing in psychiatric disorders

PloS one, 2012-08, Vol.7 (8), p.e43227-e43227

2012

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Integrated Approaches for Genome-wide Interrogation of the Druggable Non-olfactory G Protein-coupled Receptor Superfamily

The Journal of biological chemistry, 2015-08, Vol.290 (32), p.19471-19477

2015

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PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

Nature structural & molecular biology, 2015-05, Vol.22 (5), p.362-369

2015

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In silico design of novel probes for the atypical opioid receptor MRGPRX2

Nature chemical biology, 2017-05, Vol.13 (5), p.529-536

2017

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The Presynaptic Component of the Serotonergic System is Required for Clozapine's Efficacy

Neuropsychopharmacology (New York, N.Y.), 2011-02, Vol.36 (3), p.638-651

2011

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The Multiplicity of Serotonin Receptors: Uselessly Diverse Molecules or an Embarrassment of Riches?

The Neuroscientist, 2000-08, Vol.6 (4), p.252-262

2000

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Evidence for a Model of Agonist-induced Activation of 5-Hydroxytryptamine 2A Serotonin Receptors That Involves the Disruption of a Strong Ionic Interaction between Helices 3 and 6

The Journal of biological chemistry, 2002-03, Vol.277 (13), p.11441-11449

2002

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Author Correction: PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

Nature structural & molecular biology, 2024-03, Vol.31 (3), p.578-578

2024

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Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia

Nature reviews. Drug discovery, 2004-04, Vol.3 (4), p.353-359

2004

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p90 Ribosomal S6 Kinase 2 Exerts a Tonic Brake on G Protein-Coupled Receptor Signaling

Proceedings of the National Academy of Sciences - PNAS, 2006-03, Vol.103 (12), p.4717-4722

2006

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Mast Cell Degranulation and Fibroblast Activation in the Morphine-induced Spinal Mass: Role of Mas-related G Protein-coupled Receptor Signaling

Anesthesiology (Philadelphia), 2019-07, Vol.131 (1), p.132-147

2019

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G-protein-coupled receptors at a glance

Journal of cell science, 2003-12, Vol.116 (Pt 24), p.4867-4869

2003

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Molecular biology of serotonin receptors structure and function at the molecular level

Current topics in medicinal chemistry, 2002-06, Vol.2 (6), p.507-528

2002

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Deorphanization of Novel Peptides and Their Receptors

The AAPS journal, 2010-09, Vol.12 (3), p.378-384

2010

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Assessing serotonin receptor mRNA editing frequency by a novel ultra high-throughput sequencing method

Nucleic acids research, 2010-06, Vol.38 (10), p.e118-e118

2010

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Screening the receptorome yields validated molecular targets for drug discovery

Current pharmaceutical design, 2006-05, Vol.12 (14), p.1785-1795

2006

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Genetic deletion of p90 ribosomal S6 kinase 2 alters patterns of 5-hydroxytryptamine 2A serotonin receptor functional selectivity

Molecular pharmacology, 2010-03, Vol.77 (3), p.327-338

2010

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Antagonist Functional Selectivity: 5-HT 2A Serotonin Receptor Antagonists Differentially Regulate 5-HT 2A Receptor Protein Level In Vivo

The Journal of pharmacology and experimental therapeutics, 2011-10, Vol.339 (1), p.99-105

2011

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Structure, function and pharmacology of human itch GPCRs

Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65

Discovery and Characterization of Novel GPR39 Agonists Allosterically Modulated by Zinc

Biased signaling of the proton‐sensing receptor OGR1 by benzodiazepines

Antagonist functional selectivity: 5-HT2A serotonin receptor antagonists differentially regulate 5-HT2A receptor protein level in vivo

The Human Polyomavirus, JCV, Uses Serotonin Receptors to Infect Cells

Tuning up the right signal: chemical and genetic approaches to study GPCR functions

Quantitative analysis of focused a-to-I RNA editing sites by ultra-high-throughput sequencing in psychiatric disorders

Integrated Approaches for Genome-wide Interrogation of the Druggable Non-olfactory G Protein-coupled Receptor Superfamily

PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

In silico design of novel probes for the atypical opioid receptor MRGPRX2

The Presynaptic Component of the Serotonergic System is Required for Clozapine's Efficacy

The Multiplicity of Serotonin Receptors: Uselessly Diverse Molecules or an Embarrassment of Riches?

Evidence for a Model of Agonist-induced Activation of 5-Hydroxytryptamine 2A Serotonin Receptors That Involves the Disruption of a Strong Ionic Interaction between Helices 3 and 6

Author Correction: PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia

p90 Ribosomal S6 Kinase 2 Exerts a Tonic Brake on G Protein-Coupled Receptor Signaling

Mast Cell Degranulation and Fibroblast Activation in the Morphine-induced Spinal Mass: Role of Mas-related G Protein-coupled Receptor Signaling

G-protein-coupled receptors at a glance

Molecular biology of serotonin receptors structure and function at the molecular level

Deorphanization of Novel Peptides and Their Receptors

Assessing serotonin receptor mRNA editing frequency by a novel ultra high-throughput sequencing method

Screening the receptorome yields validated molecular targets for drug discovery

Genetic deletion of p90 ribosomal S6 kinase 2 alters patterns of 5-hydroxytryptamine 2A serotonin receptor functional selectivity

Antagonist Functional Selectivity: 5-HT 2A Serotonin Receptor Antagonists Differentially Regulate 5-HT 2A Receptor Protein Level In Vivo

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