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Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin

Molecular and Cellular Biology, 2013-04, Vol.33 (7), p.1357-1367

2013

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A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease

Nature medicine, 2015-03, Vol.21 (3), p.276-280

2015

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Structural and Functional Roles of the Conserved Cysteine Residues of the Redox-regulated Import Receptor Mia40 in the Intermembrane Space of Mitochondria

The Journal of biological chemistry, 2009-01, Vol.284 (3), p.1353-1363

2009

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InterAKTions with FKBPs--mutational and pharmacological exploration

PloS one, 2013-02, Vol.8 (2), p.e57508-e57508

2013

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The J domain-related cochaperone Tim16 is a constituent of the mitochondrial TIM23 preprotein translocase

Nature structural & molecular biology, 2004-03, Vol.11 (3), p.234-241

2004

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Integrative analysis of the mitochondrial proteome in yeast

PLoS biology, 2004-06, Vol.2 (6), p.e160-804

2004

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XAP2 inhibits glucocorticoid receptor activity in mammalian cells

FEBS letters, 2009-05, Vol.583 (9), p.1493-1498

2009

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Selective inhibitors of the FK506-binding protein 51 by induced fit

Nature chemical biology, 2015-01, Vol.11 (1), p.33-37

2015

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Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes

Molecular biology of the cell, 2004-03, Vol.15 (3), p.1445-1458

2004

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A Disulfide Relay System in the Intermembrane Space of Mitochondria that Mediates Protein Import

Cell, 2005-07, Vol.121 (7), p.1059-1069

2005

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FKBPs and the Akt/mTOR pathway

Cell cycle (Georgetown, Tex.), 2013-08, Vol.12 (15), p.2366-2370

2013

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Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties

The Journal of neuroscience, 2015-06, Vol.35 (24), p.9007-9016

2015

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Rational Design and Asymmetric Synthesis of Potent and Neurotrophic Ligands for FK506-Binding Proteins (FKBPs)

Angewandte Chemie (International ed.), 2015-01, Vol.54 (1), p.345-348

International ed. in English, 2015

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Evaluation of Synthetic FK506 Analogues as Ligands for the FK506-Binding Proteins 51 and 52

Journal of medicinal chemistry, 2012-05, Vol.55 (9), p.4114-4122

2012

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Crystal Structures of the Free and Ligand-Bound FK1–FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge

Journal of molecular biology, 2013-11, Vol.425 (22), p.4134-4144

2013

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Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52

Journal of medicinal chemistry, 2012-05, Vol.55 (9), p.4123-4131

2012

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Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90

Acta crystallographica. Section D, Biological crystallography., 2011-06, Vol.67 (6), p.549-559

2011

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Increasing the Efficiency of Ligands for FK506-Binding Protein 51 by Conformational Control

Journal of medicinal chemistry, 2013-05, Vol.56 (10), p.3922-3935

2013

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Fluorescent Probes to Characterise FK506‐Binding Proteins

Chembiochem : a European journal of chemical biology, 2009-05, Vol.10 (8), p.1402-1410

2009

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Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions

FEBS letters, 2005-01, Vol.579 (1), p.179-184

2005

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Rationales Design und asymmetrische Synthese potenter neuritotropher Liganden für FK506-bindende Proteine (FKBPs)

Angewandte Chemie, 2015-01, Vol.127 (1), p.352-355

2015

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Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties

The Journal of neuroscience, 2015-06, Vol.35 (24), p.9007-9016

2015

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Tim50, a novel component of the TIM23 preprotein translocase of mitochondria

The EMBO journal, 2003-02, Vol.22 (4), p.816-825

2003

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Selective Targeting of Disease-Relevant Protein Binding Domains by O-Phosphorylated Natural Product Derivatives

ACS chemical biology, 2011-10, Vol.6 (10), p.1008-1014

2011

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Facile Synthesis of a Fluorescent Cyclosporin A Analogue To Study Cyclophilin 40 and Cyclophilin 18 Ligands

ACS medicinal chemistry letters, 2010-12, Vol.1 (9), p.536-539

2010

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Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin

A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease

Structural and Functional Roles of the Conserved Cysteine Residues of the Redox-regulated Import Receptor Mia40 in the Intermembrane Space of Mitochondria

InterAKTions with FKBPs--mutational and pharmacological exploration

The J domain-related cochaperone Tim16 is a constituent of the mitochondrial TIM23 preprotein translocase

Integrative analysis of the mitochondrial proteome in yeast

XAP2 inhibits glucocorticoid receptor activity in mammalian cells

Selective inhibitors of the FK506-binding protein 51 by induced fit

Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes

A Disulfide Relay System in the Intermembrane Space of Mitochondria that Mediates Protein Import

FKBPs and the Akt/mTOR pathway

Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties

Rational Design and Asymmetric Synthesis of Potent and Neurotrophic Ligands for FK506-Binding Proteins (FKBPs)

Evaluation of Synthetic FK506 Analogues as Ligands for the FK506-Binding Proteins 51 and 52

Crystal Structures of the Free and Ligand-Bound FK1–FK2 Domain Segment of FKBP52 Reveal a Flexible Inter-Domain Hinge

Exploration of Pipecolate Sulfonamides as Binders of the FK506-Binding Proteins 51 and 52

Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90

Increasing the Efficiency of Ligands for FK506-Binding Protein 51 by Conformational Control

Fluorescent Probes to Characterise FK506‐Binding Proteins

Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions

Rationales Design und asymmetrische Synthese potenter neuritotropher Liganden für FK506-bindende Proteine (FKBPs)

Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties

Tim50, a novel component of the TIM23 preprotein translocase of mitochondria

Selective Targeting of Disease-Relevant Protein Binding Domains by O-Phosphorylated Natural Product Derivatives

Facile Synthesis of a Fluorescent Cyclosporin A Analogue To Study Cyclophilin 40 and Cyclophilin 18 Ligands

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