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Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-Titer Hepatitis B Virus Carrier Mice

Gastroenterology (New York, N.Y. 1943), 2020-05, Vol.158 (6), p.1762-1775.e9

2020

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Therapeutic vaccination for chronic hepatitis B

Current opinion in virology, 2017-04, Vol.23, p.75-81

2017

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Depletion of T cells via Inducible Caspase 9 Increases Safety of Adoptive T-Cell Therapy Against Chronic Hepatitis B

Frontiers in immunology, 2021-10, Vol.12, p.734246

2021

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Editorial: Targeting the Immune System to Treat Hepatitis B Virus Infection

Frontiers in immunology, 2022-03, Vol.13, p.868616-868616

2022

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Combination of DNA prime--adenovirus boost immunization with entecavir elicits sustained control of chronic hepatitis B in the woodchuck model

PLoS pathogens, 2013-06, Vol.9 (6), p.e1003391-e1003391

2013

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PD-L1 Silencing in Liver Using siRNAs Enhances Efficacy of Therapeutic Vaccination for Chronic Hepatitis B

Biomolecules (Basel, Switzerland), 2022-03, Vol.12 (3), p.470

2022

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CARs derived from broadly neutralizing, human monoclonal antibodies identified by single B cell sorting target hepatitis B virus-positive cells

Frontiers in immunology, 2024-04, Vol.15, p.1340619-1340619

2024

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DNA Prime-Adenovirus Boost Immunization Induces a Vigorous and Multifunctional T-Cell Response against Hepadnaviral Proteins in the Mouse and Woodchuck Model

Journal of Virology, 2012-09, Vol.86 (17), p.9297-9310

2012

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Immunogenicity and Antiviral Response of Therapeutic Hepatitis B Vaccination in a Mouse Model of HBeAg-Negative, Persistent HBV Infection

Vaccines (Basel), 2021-07, Vol.9 (8), p.841

2021

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Evaluation of the Effect of CD70 Co-Expression on CD8 T Cell Response in Protein-Prime MVA-Boost Vaccination in Mice

Vaccines (Basel), 2023-01, Vol.11 (2), p.245

2023

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The expression of PD-1 ligands and their involvement in regulation of T cell functions in acute and chronic woodchuck hepatitis virus infection

PloS one, 2011-10, Vol.6 (10), p.e26196-e26196

2011

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Intramolecular recombination enables the formation of hepatitis B virus (HBV) cccDNA in mice after HBV genome transfer using recombinant AAV vectors

Antiviral research, 2021-10, Vol.194, p.105140-105140, Article 105140

2021

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Introducing adjuvant-loaded particulate hepatitis B core antigen as an alternative therapeutic hepatitis B vaccine component

JHEP reports, 2024-04, Vol.6 (4), p.100997-100997, Article 100997

2024

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Novel Woodchuck Hepatitis Virus (WHV) Transgene Mouse Models Show Sex-Dependent WHV Replicative Activity and Development of Spontaneous Immune Responses to WHV Proteins

Journal of Virology, 2014-02, Vol.88 (3), p.1573-1581

2014

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Polarization of Monocytic Myeloid-Derived Suppressor Cells by Hepatitis B Surface Antigen Is Mediated via ERK/IL-6/STAT3 Signaling Feedback and Restrains the Activation of T Cells in Chronic Hepatitis B Virus Infection

The Journal of immunology (1950), 2015-11, Vol.195 (10), p.4873-4883

2015

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Activation of CD4 T cells during prime immunization determines the success of a therapeutic hepatitis B vaccine in HBV-carrier mouse models

Journal of hepatology, 2023-04, Vol.78 (4), p.717-730

2023

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Synergy of therapeutic heterologous prime-boost hepatitis B vaccination with CpG-application to improve immune control of persistent HBV infection

Scientific reports, 2019-07, Vol.9 (1), p.10808-10, Article 10808

2019

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Low hepatitis B virus–specific T‐cell response in males correlates with high regulatory T‐cell numbers in murine models

Hepatology (Baltimore, Md.), 2017-07, Vol.66 (1), p.69-83

2017

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Production and Purification of Adeno-Associated Viral Vectors for the Development of Immune-Competent Mouse Models of Persistent Hepatitis B Virus Replication

Methods in molecular biology (Clifton, N.J.), 2024, Vol.2837, p.207

2024

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A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection

Nature (London), 2024-07, Vol.631 (8022), p.867-875

2024

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The Woodchuck, a Nonprimate Model for Immunopathogenesis and Therapeutic Immunomodulation in Chronic Hepatitis B Virus Infection

Cold Spring Harbor perspectives in medicine, 2015-12, Vol.5 (12), p.a021451

2015

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Therapeutic vaccination and immunomodulation in the treatment of chronic hepatitis B: preclinical studies in the woodchuck

Medical microbiology and immunology, 2015-02, Vol.204 (1), p.103-114

2015

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Dynamic, Helminth-Induced Immune Modulation Influences the Outcome of Acute and Chronic Hepatitis B Virus Infection

The Journal of infectious diseases, 2020-04, Vol.221 (9), p.1448-1461

2020

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Protein-prime/modified vaccinia virus Ankara vector-boost vaccination overcomes tolerance in high-antigenemic HBV-transgenic mice

Vaccine, 2016-02, Vol.34 (7), p.923-932

2016

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Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-Titer Hepatitis B Virus Carrier Mice

Therapeutic vaccination for chronic hepatitis B

Depletion of T cells via Inducible Caspase 9 Increases Safety of Adoptive T-Cell Therapy Against Chronic Hepatitis B

Editorial: Targeting the Immune System to Treat Hepatitis B Virus Infection

Combination of DNA prime--adenovirus boost immunization with entecavir elicits sustained control of chronic hepatitis B in the woodchuck model

PD-L1 Silencing in Liver Using siRNAs Enhances Efficacy of Therapeutic Vaccination for Chronic Hepatitis B

CARs derived from broadly neutralizing, human monoclonal antibodies identified by single B cell sorting target hepatitis B virus-positive cells

DNA Prime-Adenovirus Boost Immunization Induces a Vigorous and Multifunctional T-Cell Response against Hepadnaviral Proteins in the Mouse and Woodchuck Model

Immunogenicity and Antiviral Response of Therapeutic Hepatitis B Vaccination in a Mouse Model of HBeAg-Negative, Persistent HBV Infection

Evaluation of the Effect of CD70 Co-Expression on CD8 T Cell Response in Protein-Prime MVA-Boost Vaccination in Mice

The expression of PD-1 ligands and their involvement in regulation of T cell functions in acute and chronic woodchuck hepatitis virus infection

Intramolecular recombination enables the formation of hepatitis B virus (HBV) cccDNA in mice after HBV genome transfer using recombinant AAV vectors

Introducing adjuvant-loaded particulate hepatitis B core antigen as an alternative therapeutic hepatitis B vaccine component

Novel Woodchuck Hepatitis Virus (WHV) Transgene Mouse Models Show Sex-Dependent WHV Replicative Activity and Development of Spontaneous Immune Responses to WHV Proteins

Polarization of Monocytic Myeloid-Derived Suppressor Cells by Hepatitis B Surface Antigen Is Mediated via ERK/IL-6/STAT3 Signaling Feedback and Restrains the Activation of T Cells in Chronic Hepatitis B Virus Infection

Activation of CD4 T cells during prime immunization determines the success of a therapeutic hepatitis B vaccine in HBV-carrier mouse models

Synergy of therapeutic heterologous prime-boost hepatitis B vaccination with CpG-application to improve immune control of persistent HBV infection

Low hepatitis B virus–specific T‐cell response in males correlates with high regulatory T‐cell numbers in murine models

Production and Purification of Adeno-Associated Viral Vectors for the Development of Immune-Competent Mouse Models of Persistent Hepatitis B Virus Replication

A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection

The Woodchuck, a Nonprimate Model for Immunopathogenesis and Therapeutic Immunomodulation in Chronic Hepatitis B Virus Infection

Therapeutic vaccination and immunomodulation in the treatment of chronic hepatitis B: preclinical studies in the woodchuck

Dynamic, Helminth-Induced Immune Modulation Influences the Outcome of Acute and Chronic Hepatitis B Virus Infection

Protein-prime/modified vaccinia virus Ankara vector-boost vaccination overcomes tolerance in high-antigenemic HBV-transgenic mice

Amino Acid Substitutions within HLA-B27-Restricted T Cell Epitopes Prevent Recognition by Hepatitis Delta Virus-Specific CD8 + T Cells

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