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Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

Nature biotechnology, 2011-02, Vol.29 (2), p.154-157

2011

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mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo

PloS one, 2016-04, Vol.11 (4), p.e0154001-e0154001

2016

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Correction: mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo

PloS one, 2018-05, Vol.13 (5), p.e0197705-e0197705

2018

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Recent Developments in mRNA-Based Protein Supplementation Therapy to Target Lung Diseases

Molecular therapy, 2019-04, Vol.27 (4), p.803-823

2019

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The chitinase-like protein YKL-40 modulates cystic fibrosis lung disease

PloS one, 2011-09, Vol.6 (9), p.e24399-e24399

2011

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Comparative targeting analysis of KLF1, BCL11A, and HBG1/2 in CD34 + HSPCs by CRISPR/Cas9 for the induction of fetal hemoglobin

Scientific reports, 2020-06, Vol.10 (1), p.10133-10133, Article 10133

2020

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A Comparative Study of the Bone Regenerative Effect of Chemically Modified RNA Encoding BMP-2 or BMP-9

The AAPS journal, 2017-03, Vol.19 (2), p.438-446

2017

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Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification

Molecular therapy. Nucleic acids, 2018-09, Vol.12, p.530-542

2018

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Chemically modified hCFTR mRNAs recuperate lung function in a mouse model of cystic fibrosis

Scientific reports, 2018-11, Vol.8 (1), p.16776-14, Article 16776

2018

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Transcriptomic profile of cystic fibrosis patients identifies type I interferon response and ribosomal stalk proteins as potential modifiers of disease severity

PloS one, 2017-08, Vol.12 (8), p.e0183526-e0183526

2017

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G-Protein-coupled Receptor Polymorphisms Are Associated with Asthma in a Large German Population

American journal of respiratory and critical care medicine, 2005-06, Vol.171 (12), p.1358-1362

2005

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CXCR1 and CXCR2 haplotypes synergistically modulate cystic fibrosis lung disease

The European respiratory journal, 2012-06, Vol.39 (6), p.1385-1390

2012

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Germline Gene Editing in Chickens by Efficient CRISPR-Mediated Homologous Recombination in Primordial Germ Cells

PloS one, 2016-04, Vol.11 (4), p.e0154303-e0154303

2016

Volltextzugriff (PDF)

A bioactive collagen membrane that enhances bone regeneration

Journal of biomedical materials research. Part B, Applied biomaterials, 2019-08, Vol.107 (6), p.1824-1832

2019

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In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency

Nature biotechnology, 2015-06, Vol.33 (6), p.584-586

2015

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Functional Toll-Like Receptor (TLR)2 polymorphisms in the susceptibility to inflammatory bowel disease

PloS one, 2017-04, Vol.12 (4), p.e0175180-e0175180

2017

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Modified Foxp3 mRNA protects against asthma through an IL-10-dependent mechanism

The Journal of clinical investigation, 2013-03, Vol.123 (3), p.1216-1228

2013

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The Interleukin-17 Induced Activation and Increased Survival of Equine Neutrophils Is Insensitive to Glucocorticoids

PloS one, 2016-05, Vol.11 (5), p.e0154755-e0154755

2016

Volltextzugriff (PDF)

Pyrosequencing Unveils Cystic Fibrosis Lung Microbiome Differences Associated with a Severe Lung Function Decline

PloS one, 2016-06, Vol.11 (6), p.e0156807-e0156807

2016

Volltextzugriff (PDF)

The Effect of Strict Segregation on Pseudomonas aeruginosa in Cystic Fibrosis Patients

PloS one, 2016-06, Vol.11 (6), p.e0157189-e0157189

2016

Volltextzugriff (PDF)

Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress

Nature neuroscience, 2003-10, Vol.6 (10), p.1100-1107

2003

Volltextzugriff (PDF)

Inhibition of Suicidal Erythrocyte Death by Volasertib

Cellular physiology and biochemistry, 2017-01, Vol.43 (4), p.1472-1486

2017

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RNA ImmunoGenic Assay: A Method to Detect Immunogenicity of in vitro Transcribed mRNA in Human Whole Blood

Bio-protocol, 2020-12, Vol.10 (24), p.e3850-e3850

2020

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CX3CR1 Polymorphisms Are Associated with Atopy but Not Asthma in German Children

International archives of allergy and immunology, 2007-01, Vol.144 (1), p.91-94

2007

Volltextzugriff (PDF)

The oral and craniofacial relevance of chemically modified RNA therapeutics

Discovery medicine, 2016-01, Vol.21 (113), p.35-39

2016

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Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo

Correction: mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo

Recent Developments in mRNA-Based Protein Supplementation Therapy to Target Lung Diseases

The chitinase-like protein YKL-40 modulates cystic fibrosis lung disease

Comparative targeting analysis of KLF1, BCL11A, and HBG1/2 in CD34 + HSPCs by CRISPR/Cas9 for the induction of fetal hemoglobin

A Comparative Study of the Bone Regenerative Effect of Chemically Modified RNA Encoding BMP-2 or BMP-9

Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification

Chemically modified hCFTR mRNAs recuperate lung function in a mouse model of cystic fibrosis

Transcriptomic profile of cystic fibrosis patients identifies type I interferon response and ribosomal stalk proteins as potential modifiers of disease severity

G-Protein-coupled Receptor Polymorphisms Are Associated with Asthma in a Large German Population

CXCR1 and CXCR2 haplotypes synergistically modulate cystic fibrosis lung disease

Germline Gene Editing in Chickens by Efficient CRISPR-Mediated Homologous Recombination in Primordial Germ Cells

A bioactive collagen membrane that enhances bone regeneration

In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency

Functional Toll-Like Receptor (TLR)2 polymorphisms in the susceptibility to inflammatory bowel disease

Modified Foxp3 mRNA protects against asthma through an IL-10-dependent mechanism

The Interleukin-17 Induced Activation and Increased Survival of Equine Neutrophils Is Insensitive to Glucocorticoids

Pyrosequencing Unveils Cystic Fibrosis Lung Microbiome Differences Associated with a Severe Lung Function Decline

The Effect of Strict Segregation on Pseudomonas aeruginosa in Cystic Fibrosis Patients

Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress

Inhibition of Suicidal Erythrocyte Death by Volasertib

RNA ImmunoGenic Assay: A Method to Detect Immunogenicity of in vitro Transcribed mRNA in Human Whole Blood

CX3CR1 Polymorphisms Are Associated with Atopy but Not Asthma in German Children

The oral and craniofacial relevance of chemically modified RNA therapeutics

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