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Structural Insights into the Catalytic Mechanism of a Family 18 Exo-Chitinase

Proceedings of the National Academy of Sciences - PNAS, 2001-07, Vol.98 (16), p.8979-8984

2001

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PDK1, the master regulator of AGC kinase signal transduction

Seminars in cell & developmental biology, 2004-04, Vol.15 (2), p.161-170

2004

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Psammaplin A, a chitinase inhibitor isolated from the fijian marine sponge Aplysinella rhax

Bioorganic & medicinal chemistry, 2002-04, Vol.10 (4), p.1123-1128

2002

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A Genetic Screen Identifies Factors Required for Toxoplasma Differentiation into Latent Forms

European journal of microbiology & immunology, 2024-06, Vol.14 (S1), p.15

2024

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Analysis of the LKB1-STRAD-MO25 complex

Journal of cell science, 2004-12, Vol.117 (Pt 26), p.6365-6375

2004

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Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates

The EMBO journal, 2004-10, Vol.23 (20), p.3918-3928

2004

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High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site

The EMBO journal, 2002-08, Vol.21 (16), p.4219-4228

2002

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Structural basis for UCN-01 (7-hydroxystaurosporine) specificity and PDK1 (3-phosphoinositide-dependent protein kinase-1) inhibition

Biochemical journal, 2003-10, Vol.375 (Pt 2), p.255-262

2003

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Role of T-loop Phosphorylation in PDK1 Activation, Stability, and Substrate Binding

The Journal of biological chemistry, 2005-05, Vol.280 (19), p.18797-18802

2005

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Interactions of LY333531 and Other Bisindolyl Maleimide Inhibitors with PDK1

Structure (London), 2004-02, Vol.12 (2), p.215-226

2004

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Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF- mu B Activation

Cell, 2009-03, Vol.136 (6), p.1098-1109

2009

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Purification, crystallization and preliminary X-ray diffraction of a proteolytic fragment of PDK1 containing the pleckstrin homology domain

Acta crystallographica. Section D, Biological crystallography., 2004-02, Vol.60 (2), p.314-316

2004

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Structural studies of 3-phosphoinositide dependent protein kinase-1 (PDK1)

Komander, D

2004

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ChemInform Abstract: Psammaplin A, a Chitinase Inhibitor Isolated from the Fijian Marine Sponge Aplysinella Rhax

ChemInform, 2002-05, Vol.33 (20), p.no-no

2002

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OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer

Cell death and differentiation, 2020-05, Vol.27 (5), p.1457-1474

2020

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Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

EMBO reports, 2009-05, Vol.10 (5), p.466-473

2009

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On the correlation of angular distributions of keV ions and trajectory-dependent electronic excitations in transmission channelling geometry

Journal of physics. Conference series, 2022-10, Vol.2326 (1), p.12008

2022

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Lysine 27 Ubiquitination of the Mitochondrial Transport Protein Miro Is Dependent on Serine 65 of the Parkin Ubiquitin Ligase

The Journal of biological chemistry, 2014-05, Vol.289 (21), p.14569-14582

2014

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Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne

Nature (London), 2016-10, Vol.538 (7625), p.402-405

2016

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Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

EMBO reports, 2011-04, Vol.12 (4), p.350-357

2011

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Activation mechanism of PINK1

Nature (London), 2022-02, Vol.602 (7896), p.328-335

2022

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Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymes

Nature communications, 2023-03, Vol.14 (1), p.1661-1661, Article 1661

2023

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Recognition of Polyubiquitin Isoforms by the Multiple Ubiquitin Binding Modules of Isopeptidase T

The Journal of biological chemistry, 2008-07, Vol.283 (28), p.19581-19592

2008

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Hydrogen site location in ultrathin vanadium layers by N-15 nuclear reaction analysis

Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms, 2019-09, Vol.455, p.57-60

2019

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Structural Insights into the Catalytic Mechanism of a Family 18 Exo-Chitinase

PDK1, the master regulator of AGC kinase signal transduction

Psammaplin A, a chitinase inhibitor isolated from the fijian marine sponge Aplysinella rhax

A Genetic Screen Identifies Factors Required for Toxoplasma Differentiation into Latent Forms

Analysis of the LKB1-STRAD-MO25 complex

Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates

High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site

Structural basis for UCN-01 (7-hydroxystaurosporine) specificity and PDK1 (3-phosphoinositide-dependent protein kinase-1) inhibition

Role of T-loop Phosphorylation in PDK1 Activation, Stability, and Substrate Binding

Interactions of LY333531 and Other Bisindolyl Maleimide Inhibitors with PDK1

Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF- mu B Activation

Purification, crystallization and preliminary X-ray diffraction of a proteolytic fragment of PDK1 containing the pleckstrin homology domain

Structural studies of 3-phosphoinositide dependent protein kinase-1 (PDK1)

ChemInform Abstract: Psammaplin A, a Chitinase Inhibitor Isolated from the Fijian Marine Sponge Aplysinella Rhax

OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer

Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

On the correlation of angular distributions of keV ions and trajectory-dependent electronic excitations in transmission channelling geometry

Lysine 27 Ubiquitination of the Mitochondrial Transport Protein Miro Is Dependent on Serine 65 of the Parkin Ubiquitin Ligase

Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

Activation mechanism of PINK1

USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma

Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymes

Recognition of Polyubiquitin Isoforms by the Multiple Ubiquitin Binding Modules of Isopeptidase T

Hydrogen site location in ultrathin vanadium layers by N-15 nuclear reaction analysis

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