UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

A thallium-sensitive, fluorescence-based assay for detecting and characterizing potassium channel modulators in mammalian cells

Journal of biomolecular screening, 2004-12, Vol.9 (8), p.671-677

2004

Volltextzugriff (PDF)

Criterion-related validity of the cultural web when assessing safety culture

Safety science, 2019-01, Vol.111, p.49-66

2019

Volltextzugriff (PDF)

Functionalized Cyclopentadienyl Titanium Organometallic Compounds as New Antitumor Drugs

Organometallics, 2004-01, Vol.23 (2), p.288-292

2004

Volltextzugriff (PDF)

Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954

Oncogene, 2001-11, Vol.20 (53), p.7797-7803

2001

Volltextzugriff (PDF)

Insulin receptor in Aplysia neurons: characterization, molecular cloning, and modulation of ion currents

The Journal of neuroscience, 1996-03, Vol.16 (5), p.1645-1658

1996

Volltextzugriff (PDF)

Selective ablation of human cancer cells by telomerase-specific adenoviral suicide gene therapy vectors expressing bacterial nitroreductase

Oncogene, 2003-01, Vol.22 (3), p.370-380

2003

Volltextzugriff (PDF)

BL-1249 [(5,6,7,8-tetrahydro-naphthalen-1-yl)-[2-(1H-tetrazol-5-yl)-phenyl]-amine]: a putative potassium channel opener with bladder-relaxant properties

The Journal of pharmacology and experimental therapeutics, 2005-04, Vol.313 (1), p.250-259

2005

Volltextzugriff (PDF)

Quinone Reductase–Mediated Nitro-Reduction: Clinical Applications

Methods in Enzymology, 2004, Vol.382, p.194-221

2004

Volltextzugriff (PDF)

Nitrobenzocyclophosphamides as potential prodrugs for bioreductive activation: synthesis, stability, enzymatic reduction, and antiproliferative activity in cell culture

Bioorganic & medicinal chemistry, 2003-09, Vol.11 (19), p.4171-4178

2003

Volltextzugriff (PDF)

Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2 : A novel co-substrate-mediated antitumor prodrug therapy

Cancer research (Chicago, Ill.), 2000-08, Vol.60 (15), p.4179-4186

2000

Volltextzugriff (PDF)

Nitroaryl Phosphoramides as Novel Prodrugs for E. coli Nitroreductase Activation in Enzyme Prodrug Therapy

Journal of medicinal chemistry, 2003-11, Vol.46 (23), p.4818-4821

2003

Volltextzugriff (PDF)

Fluorine Substitution Can Block CYP3A4 Metabolism-Dependent Inhibition: Identification of (S)-N-[1-(4-Fluoro-3- morpholin-4-ylphenyl)ethyl]-3- (4-fluorophenyl)acrylamide as an Orally Bioavailable KCNQ2 Opener Devoid of CYP3A4 Metabolism-Dependent Inhibition

Journal of medicinal chemistry, 2003-08, Vol.46 (18), p.3778-3781

2003

Volltextzugriff (PDF)

CB 1954: from the Walker tumor to NQO2 and VDEPT

Current pharmaceutical design, 2003-10, Vol.9 (26), p.2091-2104

2003

Volltextzugriff (PDF)

Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954

European journal of cancer (1990), 1995-12, Vol.31 (13), p.2362-2370

1995

Volltextzugriff (PDF)

The Bystander Effect of the Nitroreductase/CB 1954 Enzyme/Prodrug System Is Due to a Cell-Permeable Metabolite

Human gene therapy, 1997-04, Vol.8 (6), p.709-717

1997

Volltextzugriff (PDF)

Regulation of insulin of a unique neuronal Ca2+ pool and of neuropeptide secretion

Nature (London), 1997-01, Vol.385 (6614), p.343-346

1997

Volltextzugriff (PDF)

Brain‐Derived Neurotrophic Factor Induces Excitotoxic Sensitivity in Cultured Embryonic Rat Spinal Motor Neurons Through Activation of the Phosphatidylinositol 3‐Kinase Pathway

Journal of neurochemistry, 2000-02, Vol.74 (2), p.582-595

2000

Volltextzugriff (PDF)

Developments with targeted enzymes in cancer therapy

Current Opinion in Immunology, 1999-10, Vol.11 (5), p.579-583

1999

Volltextzugriff (PDF)

Excitotoxic Death of a Subset of Embryonic Rat Motor Neurons In Vitro

Journal of neurochemistry, 1999-02, Vol.72 (2), p.500-513

1999

Volltextzugriff (PDF)

Involvement of NADPH: cytochrome P450 reductase in the activation of indoloquinone EO9 to free radical and DNA damaging species

Biochemical pharmacology, 2001-08, Vol.62 (4), p.461-468

2001

Volltextzugriff (PDF)

( S)- N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2 H-benzo [1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)-acrylamide is a potent and efficacious KCNQ2 opener which inhibits induced hyperexcitability of rat hippocampal neurons

Bioorganic & medicinal chemistry letters, 2004-04, Vol.14 (8), p.1991-1995

2004

Volltextzugriff (PDF)

Synthesis and KCNQ2 opener activity of N-(1-benzo[1,3]dioxol-5-yl-ethyl, N-[1-(2,3-dihydro-benzofuran-5-yl)-ethyl, and N-[1-(2,3-dihydro-1 H-indol-5-yl)-ethyl acrylamides

Bioorganic & medicinal chemistry letters, 2004-09, Vol.14 (17), p.4533-4537

2004

Volltextzugriff (PDF)

The bioactivation of CB 1954 and its use as a prodrug in antibody-directed enzyme prodrug therapy (ADEPT)

Cancer and metastasis reviews, 1993-06, Vol.12 (2), p.195-212

1993

Volltextzugriff (PDF)

Self-Immolative Prodrugs: Candidates for Antibody-Directed Enzyme Prodrug Therapy in Conjunction with a Nitroreductase Enzyme

Journal of medicinal chemistry, 1994-10, Vol.37 (21), p.3452-3458

1994

Volltextzugriff (PDF)

Mechanism of cytotoxicity of anticancer platinum drugs: evidence that cis-diamminedichloroplatinum (II) and cis-diammine-(1,1-cyclobutanedicarboxylato)platinum(II) differ only in the kinetics of their interaction with DNA

Cancer research (Chicago, Ill.), 1986-04, Vol.46 (4), p.1972-1979

1986

Volltextzugriff (PDF)

1 – 25 von 155

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(142)
Mit Volltextzugriff
(123)

Publikationsform

Artikel
(155)

Sprache

Englisch
(155)

Erscheinungsjahr

n.n

Thema

Science & Technology
(147)
Life Sciences & Biomedicine
(126)
Humans
(68)
Biological And Medical Sciences
(59)
Animals
(57)
Medical Sciences
(41)
Female
(30)
Physical Sciences
(26)
Male
(23)
Pharmacology. Drug Treatments
(23)
Biochemistry & Molecular Biology
(22)
Pharmacology & Pharmacy
(22)
Chemistry
(20)
Rats
(20)
Fundamental And Applied Biological Sciences. Psychology
(18)
Adult
(17)
Oncology
(17)
Cell Line
(15)
Antineoplastic Agents
(14)
Tumor Cells, Cultured
(14)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

A thallium-sensitive, fluorescence-based assay for detecting and characterizing potassium channel modulators in mammalian cells

Criterion-related validity of the cultural web when assessing safety culture

Functionalized Cyclopentadienyl Titanium Organometallic Compounds as New Antitumor Drugs

Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954

Insulin receptor in Aplysia neurons: characterization, molecular cloning, and modulation of ion currents

Selective ablation of human cancer cells by telomerase-specific adenoviral suicide gene therapy vectors expressing bacterial nitroreductase

BL-1249 [(5,6,7,8-tetrahydro-naphthalen-1-yl)-[2-(1H-tetrazol-5-yl)-phenyl]-amine]: a putative potassium channel opener with bladder-relaxant properties

Quinone Reductase–Mediated Nitro-Reduction: Clinical Applications

Nitrobenzocyclophosphamides as potential prodrugs for bioreductive activation: synthesis, stability, enzymatic reduction, and antiproliferative activity in cell culture

Bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by human NAD(P)H quinone oxidoreductase 2 : A novel co-substrate-mediated antitumor prodrug therapy

Nitroaryl Phosphoramides as Novel Prodrugs for E. coli Nitroreductase Activation in Enzyme Prodrug Therapy

Fluorine Substitution Can Block CYP3A4 Metabolism-Dependent Inhibition: Identification of (S)-N-[1-(4-Fluoro-3- morpholin-4-ylphenyl)ethyl]-3- (4-fluorophenyl)acrylamide as an Orally Bioavailable KCNQ2 Opener Devoid of CYP3A4 Metabolism-Dependent Inhibition

CB 1954: from the Walker tumor to NQO2 and VDEPT

Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954

The Bystander Effect of the Nitroreductase/CB 1954 Enzyme/Prodrug System Is Due to a Cell-Permeable Metabolite

Regulation of insulin of a unique neuronal Ca2+ pool and of neuropeptide secretion

Brain‐Derived Neurotrophic Factor Induces Excitotoxic Sensitivity in Cultured Embryonic Rat Spinal Motor Neurons Through Activation of the Phosphatidylinositol 3‐Kinase Pathway

Developments with targeted enzymes in cancer therapy

Excitotoxic Death of a Subset of Embryonic Rat Motor Neurons In Vitro

Involvement of NADPH: cytochrome P450 reductase in the activation of indoloquinone EO9 to free radical and DNA damaging species

( S)- N-[1-(4-Cyclopropylmethyl-3,4-dihydro-2 H-benzo [1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)-acrylamide is a potent and efficacious KCNQ2 opener which inhibits induced hyperexcitability of rat hippocampal neurons

Synthesis and KCNQ2 opener activity of N-(1-benzo[1,3]dioxol-5-yl-ethyl, N-[1-(2,3-dihydro-benzofuran-5-yl)-ethyl, and N-[1-(2,3-dihydro-1 H-indol-5-yl)-ethyl acrylamides

The bioactivation of CB 1954 and its use as a prodrug in antibody-directed enzyme prodrug therapy (ADEPT)

Self-Immolative Prodrugs: Candidates for Antibody-Directed Enzyme Prodrug Therapy in Conjunction with a Nitroreductase Enzyme

Mechanism of cytotoxicity of anticancer platinum drugs: evidence that cis-diamminedichloroplatinum (II) and cis-diammine-(1,1-cyclobutanedicarboxylato)platinum(II) differ only in the kinetics of their interaction with DNA

Suchergebnisse filtern