UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 456

Sortiert nach

Peptide Inhibitors of West Nile NS3 Protease: SAR Study of Tetrapeptide Aldehyde Inhibitors

Journal of medicinal chemistry, 2006-11, Vol.49 (22), p.6585-6590

2006

Link zum Volltext

Verfügbarkeit prüfen

Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS

Science (American Association for the Advancement of Science), 2023-08, Vol.381 (6659), p.794-799

2023

Link zum Volltext

Verfügbarkeit prüfen

Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy

Nature (London), 2024-05, Vol.629 (8013), p.919-926

2024

Link zum Volltext

Verfügbarkeit prüfen

Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors

Journal of medicinal chemistry, 2023-01, Vol.66 (1), p.149-169

2023

Link zum Volltext

Verfügbarkeit prüfen

Discovery of dual-activity small-molecule ligands of Pseudomonas aeruginosa LpxA and LpxD using SPR and X-ray crystallography

Scientific reports, 2019-10, Vol.9 (1), p.15450-12, Article 15450

2019

Link zum Volltext

Verfügbarkeit prüfen

Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis

Journal of antimicrobial chemotherapy, 2008-10, Vol.62 (4), p.713-719

2008

Link zum Volltext

Verfügbarkeit prüfen

Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitors

Bioorganic & medicinal chemistry letters, 2006, Vol.16 (1), p.40-43

2006

Link zum Volltext

Verfügbarkeit prüfen

Synthesis and antitubercular activity of 7-(R)-and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824

Bioorganic & medicinal chemistry, 2008-04, Vol.18 (7), p.2256-2262

2008

Link zum Volltext

Verfügbarkeit prüfen

Chemical failure modes of AlQ3-based OLEDs : AlQ3 hydrolysis

Physical chemistry chemical physics : PCCP, 2006-01, Vol.8 (12), p.1371-1377

2006

Link zum Volltext

Verfügbarkeit prüfen

Experimental and Theoretical Study of the Coordination of 1,2,4-Triazolato, Tetrazolato, and Pentazolato Ligands to the [K(18-crown-6)]+ Fragment

Inorganic chemistry, 2006-10, Vol.45 (21), p.8700-8710

2006

Link zum Volltext

Verfügbarkeit prüfen

Yellow fever virus NS3 protease: peptide-inhibition studies

Journal of general virology, 2007-08, Vol.88 (8), p.2223-2227

2007

Link zum Volltext

Verfügbarkeit prüfen

Synthesis, Structure, and Properties of Magnesocene Amine Adducts. Structural Distortions Arising from N−H···C5H5 - Hydrogen Bonding and Molecular Orbital Calculations Thereof

Organometallics, 2003-09, Vol.22 (20), p.4060-4069

2003

Link zum Volltext

Verfügbarkeit prüfen

Weak Carbon−Hydrogen−Nitrogen Interactions Affect the Heterocyclic Ligand Bonding Modes in Barium Complexes Containing η2-Tetrazolato and η2-Pentazolato Ligands

Inorganic chemistry, 2005-07, Vol.44 (14), p.4894-4896

2005

Link zum Volltext

Verfügbarkeit prüfen

Abstract 1261: A next generation tri-complex KRASG12C(ON) inhibitor directly targets the active, GTP-bound state of mutant RAS and may overcome resistance to KRASG12C(OFF) inhibition

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1261-1261

2021

Link zum Volltext

Verfügbarkeit prüfen

Abstract 1260: First-in-class, orally bioavailable KRASG12V(ON) tri-complex inhibitors, as single agents and in combinations, drive profound anti-tumor activity in preclinical models of KRASG12V mutant cancers

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1260-1260

2021

Link zum Volltext

Verfügbarkeit prüfen

Synthesis, Structure, Bridge−Terminal Exchange Kinetics, and Molecular Orbital Calculations of Pyrazolate-Bridged Digallium Complexes Containing Bridging Phenyl Groups

Journal of the American Chemical Society, 2003-09, Vol.125 (37), p.11152-11153

2003

Link zum Volltext

Verfügbarkeit prüfen

Finding new medicines for flaviviral targets

Novartis Foundation symposium, 2006, Vol.277, p.102

2006

Link zum Volltext

Verfügbarkeit prüfen

Abstract 526: RMC-9805, a first-in-class, mutant-selective, covalent and oral KRASG12D(ON) inhibitor that induces apoptosis and drives tumor regression in preclinical models of KRASG12D cancers

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.526-526

2023

Link zum Volltext

Verfügbarkeit prüfen

Abstract 3475: RMC-9805, a first-in-class, mutant-selective, covalent and orally bioavailable KRASG12D(ON) inhibitor, promotes cancer-associated neoantigen recognition and synergizes with immunotherapy in preclinical models

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.3475-3475

2023

Link zum Volltext

Verfügbarkeit prüfen

Abstract 3596: RM-036, a first-in-class, orally-bioavailable, Tri-Complex covalent KRASG12D(ON) inhibitor, drives profound anti-tumor activity in KRASG12D mutant tumor models

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.3596-3596

2022

Link zum Volltext

Verfügbarkeit prüfen

Abstract 3595: RMC-6291, a next-generation tri-complex KRASG12C(ON) inhibitor, outperforms KRASG12C(OFF) inhibitors in preclinical models of KRASG12C cancers

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.3595-3595

2022

Link zum Volltext

Verfügbarkeit prüfen

Abstract 3598: A first-in-class tri-complex KRASG13C(ON) inhibitor validates therapeutic targeting of KRASG13Cand drives tumor regressions in preclinical models

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.3598-3598

2022

Link zum Volltext

Verfügbarkeit prüfen

Synthesis and antitubercular activity of 7-( R)- and 7-( S)-methyl-2-nitro-6-( S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5 H-imidazo[2,1- b][1,3]oxazines, analogues of PA-824

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (7), p.2256-2262

2008

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 456

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(401)
Mit Volltextzugriff
(382)

Publikationsform

1 weiteren anzeigen...

Weniger anzeigen...

Sprache

Erscheinungsjahr

n.n

Thema

Science & Technology
(249)
Life Sciences & Biomedicine
(198)
Humans
(177)
Male
(85)
Female
(83)
Adult
(58)
Biological And Medical Sciences
(58)
Animals
(57)
Middle Aged
(53)
Physical Sciences
(48)
Medical Sciences
(43)
Aged
(42)
Old Medline
(26)
Dermatology
(25)
General & Internal Medicine
(25)
Chemistry
(23)
Medicine, General & Internal
(21)
Science & Technology - Other Topics
(21)
Mice
(20)
Multidisciplinary Sciences
(20)

15 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 30 Tagen
(1)

Menü

Weitere Dienste

Einstellungen

Peptide Inhibitors of West Nile NS3 Protease: SAR Study of Tetrapeptide Aldehyde Inhibitors

Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS

Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy

Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors

Discovery of dual-activity small-molecule ligands of Pseudomonas aeruginosa LpxA and LpxD using SPR and X-ray crystallography

Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers

Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis

Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitors

Synthesis and antitubercular activity of 7-(R)-and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824

Chemical failure modes of AlQ3-based OLEDs : AlQ3 hydrolysis

Experimental and Theoretical Study of the Coordination of 1,2,4-Triazolato, Tetrazolato, and Pentazolato Ligands to the [K(18-crown-6)]+ Fragment

Yellow fever virus NS3 protease: peptide-inhibition studies

Synthesis, Structure, and Properties of Magnesocene Amine Adducts. Structural Distortions Arising from N−H···C5H5 - Hydrogen Bonding and Molecular Orbital Calculations Thereof

Weak Carbon−Hydrogen−Nitrogen Interactions Affect the Heterocyclic Ligand Bonding Modes in Barium Complexes Containing η2-Tetrazolato and η2-Pentazolato Ligands

Abstract 1261: A next generation tri-complex KRASG12C(ON) inhibitor directly targets the active, GTP-bound state of mutant RAS and may overcome resistance to KRASG12C(OFF) inhibition

Abstract 1260: First-in-class, orally bioavailable KRASG12V(ON) tri-complex inhibitors, as single agents and in combinations, drive profound anti-tumor activity in preclinical models of KRASG12V mutant cancers

Synthesis, Structure, Bridge−Terminal Exchange Kinetics, and Molecular Orbital Calculations of Pyrazolate-Bridged Digallium Complexes Containing Bridging Phenyl Groups

Abstract 1273: Discovery of a potent, selective, and orally bioavailable SOS1 inhibitor, RMC-023, an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction

Finding new medicines for flaviviral targets

Abstract 526: RMC-9805, a first-in-class, mutant-selective, covalent and oral KRASG12D(ON) inhibitor that induces apoptosis and drives tumor regression in preclinical models of KRASG12D cancers

Abstract 3475: RMC-9805, a first-in-class, mutant-selective, covalent and orally bioavailable KRASG12D(ON) inhibitor, promotes cancer-associated neoantigen recognition and synergizes with immunotherapy in preclinical models

Abstract 3596: RM-036, a first-in-class, orally-bioavailable, Tri-Complex covalent KRASG12D(ON) inhibitor, drives profound anti-tumor activity in KRASG12D mutant tumor models

Abstract 3595: RMC-6291, a next-generation tri-complex KRASG12C(ON) inhibitor, outperforms KRASG12C(OFF) inhibitors in preclinical models of KRASG12C cancers

Abstract 3598: A first-in-class tri-complex KRASG13C(ON) inhibitor validates therapeutic targeting of KRASG13Cand drives tumor regressions in preclinical models

Synthesis and antitubercular activity of 7-( R)- and 7-( S)-methyl-2-nitro-6-( S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5 H-imidazo[2,1- b][1,3]oxazines, analogues of PA-824

Suchergebnisse filtern