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Hydrogen tunneling links protein dynamics to enzyme catalysis

Annual review of biochemistry, 2013-01, Vol.82 (1), p.471-496

2013

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Dynamically Achieved Active Site Precision in Enzyme Catalysis

Accounts of chemical research, 2015-02, Vol.48 (2), p.449-456

Klinman, Judith P.

2015

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Intrigues and Intricacies of the Biosynthetic Pathways for the Enzymatic Quinocofactors: PQQ, TTQ, CTQ, TPQ, and LTQ

Chemical reviews, 2014-04, Vol.114 (8), p.4343-4365

2014

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Importance of Protein Dynamics during Enzymatic C–H Bond Cleavage Catalysis

Biochemistry (Easton), 2013-03, Vol.52 (12), p.2068-2077

Klinman, Judith P

2013

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Control of the Position of Oxygen Delivery in Soybean Lipoxygenase-1 by Amino Acid Side Chains within a Gas Migration Channel

The Journal of biological chemistry, 2016-04, Vol.291 (17), p.9052-9059

2016

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How Do Enzymes Activate Oxygen without Inactivating Themselves?

Accounts of chemical research, 2007-05, Vol.40 (5), p.325-333

Klinman, Judith P

2007

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Update 1 of: Tunneling and Dynamics in Enzymatic Hydride Transfer

Chemical reviews, 2010-12, Vol.110 (12), p.PR41-PR67

2010

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Mediation of donor–acceptor distance in an enzymatic methyl transfer reaction

Proceedings of the National Academy of Sciences - PNAS, 2015-06, Vol.112 (26), p.7954-7959

2015

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Discovery of Hydroxylase Activity for PqqB Provides a Missing Link in the Pyrroloquinoline Quinone Biosynthetic Pathway

Journal of the American Chemical Society, 2019-03, Vol.141 (10), p.4398-4405

2019

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Irwin Rose (1926–2015)

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (34), p.10568-10569

Klinman, Judith P.

2015

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Enzyme Structure and Dynamics Affect Hydrogen Tunneling: The Impact of a Remote Side Chain (1553) in Soybean Lipoxygenase-1

Proceedings of the National Academy of Sciences - PNAS, 2008-01, Vol.105 (4), p.1146-1151

2008

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Dynamical activation of function in metalloenzymes

FEBS letters, 2023-01, Vol.597 (1), p.79-91

Klinman, Judith P.

2023

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Kinetic Detection of Orthogonal Protein and Chemical Coordinates in Enzyme Catalysis: Double Mutants of Soybean Lipoxygenase

Biochemistry (Easton), 2015-09, Vol.54 (35), p.5447-5456

2015

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Nuclear Magnetic Resonance Structure and Binding Studies of PqqD, a Chaperone Required in the Biosynthesis of the Bacterial Dehydrogenase Cofactor Pyrroloquinoline Quinone

Biochemistry (Easton), 2017-05, Vol.56 (21), p.2735-2746

2017

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Methods for Expression, Purification, and Characterization of PqqE, a Radical SAM Enzyme in the PQQ Biosynthetic Pathway

Methods in enzymology, 2018, Vol.606, p.389-420

2018

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Linking protein structure and dynamics to catalysis: the role of hydrogen tunnelling

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2006-08, Vol.361 (1472), p.1323-1331

Klinman, Judith P

2006

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Distribution and Properties of the Genes Encoding the Biosynthesis of the Bacterial Cofactor, Pyrroloquinoline Quinone

Biochemistry (Easton), 2012-03, Vol.51 (11), p.2265-2275

2012

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Functional roles of enzyme dynamics in accelerating active site chemistry: Emerging techniques and changing concepts

Current opinion in structural biology, 2022-08, Vol.75, p.102434-102434, Article 102434

2022

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Hydrogen–Deuterium Exchange Mass Spectrometry Identifies Local and Long-Distance Interactions within the Multicomponent Radical SAM Enzyme, PqqE

ACS central science, 2024-02, Vol.10 (2), p.251-263

2024

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Biogenesis of the peptide-derived redox cofactor pyrroloquinoline quinone

Current opinion in chemical biology, 2020-12, Vol.59, p.93-103

2020

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The role of tunneling in enzyme catalysis of C–H activation

Biochimica et biophysica acta, 2006-08, Vol.1757 (8), p.981-987

Klinman, Judith P.

2006

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Mechanisms Whereby Mononuclear Copper Proteins Functionalize Organic Substrates

Chemical reviews, 1996-11, Vol.96 (7), p.2541-2562

Klinman, Judith P

1996

Volltextzugriff (PDF)

Understanding Biological Hydrogen Transfer Through the Lens of Temperature Dependent Kinetic Isotope Effects

Accounts of chemical research, 2018-09, Vol.51 (9), p.1966-1974

2018

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nature of O₂ activation by the ethylene-forming enzyme 1-aminocyclopropane-1-carboxylic acid oxidase

Proceedings of the National Academy of Sciences - PNAS, 2008-02, Vol.105 (6), p.1814-1819

2008

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Impaired protein conformational landscapes as revealed in anomalous Arrhenius prefactors

Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (26), p.10520-10525

2011

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Hydrogen tunneling links protein dynamics to enzyme catalysis

Dynamically Achieved Active Site Precision in Enzyme Catalysis

Intrigues and Intricacies of the Biosynthetic Pathways for the Enzymatic Quinocofactors: PQQ, TTQ, CTQ, TPQ, and LTQ

Importance of Protein Dynamics during Enzymatic C–H Bond Cleavage Catalysis

Control of the Position of Oxygen Delivery in Soybean Lipoxygenase-1 by Amino Acid Side Chains within a Gas Migration Channel

How Do Enzymes Activate Oxygen without Inactivating Themselves?

Update 1 of: Tunneling and Dynamics in Enzymatic Hydride Transfer

Mediation of donor–acceptor distance in an enzymatic methyl transfer reaction

Discovery of Hydroxylase Activity for PqqB Provides a Missing Link in the Pyrroloquinoline Quinone Biosynthetic Pathway

Irwin Rose (1926–2015)

Enzyme Structure and Dynamics Affect Hydrogen Tunneling: The Impact of a Remote Side Chain (1553) in Soybean Lipoxygenase-1

Dynamical activation of function in metalloenzymes

Kinetic Detection of Orthogonal Protein and Chemical Coordinates in Enzyme Catalysis: Double Mutants of Soybean Lipoxygenase

Nuclear Magnetic Resonance Structure and Binding Studies of PqqD, a Chaperone Required in the Biosynthesis of the Bacterial Dehydrogenase Cofactor Pyrroloquinoline Quinone

Methods for Expression, Purification, and Characterization of PqqE, a Radical SAM Enzyme in the PQQ Biosynthetic Pathway

Linking protein structure and dynamics to catalysis: the role of hydrogen tunnelling

Distribution and Properties of the Genes Encoding the Biosynthesis of the Bacterial Cofactor, Pyrroloquinoline Quinone

Functional roles of enzyme dynamics in accelerating active site chemistry: Emerging techniques and changing concepts

Hydrogen–Deuterium Exchange Mass Spectrometry Identifies Local and Long-Distance Interactions within the Multicomponent Radical SAM Enzyme, PqqE

Biogenesis of the peptide-derived redox cofactor pyrroloquinoline quinone

The role of tunneling in enzyme catalysis of C–H activation

Mechanisms Whereby Mononuclear Copper Proteins Functionalize Organic Substrates

Understanding Biological Hydrogen Transfer Through the Lens of Temperature Dependent Kinetic Isotope Effects

nature of O₂ activation by the ethylene-forming enzyme 1-aminocyclopropane-1-carboxylic acid oxidase

Impaired protein conformational landscapes as revealed in anomalous Arrhenius prefactors

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