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NLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer’s Disease

Molecular neurobiology, 2018-03, Vol.55 (3), p.1977-1987

2018

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Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

Cell stem cell, 2013-04, Vol.12 (4), p.487-496

2013

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Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease

Nature communications, 2022-01, Vol.13 (1), p.159-19, Article 159

2022

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Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (6), p.1971-1976

2009

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Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer’s pathology

Acta neuropathologica, 2017-11, Vol.134 (5), p.769-788

2017

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Detection of a Biomarker for Alzheimer's Disease from Synthetic and Clinical Samples Using a Nanoscale Optical Biosensor

Journal of the American Chemical Society, 2005-02, Vol.127 (7), p.2264-2271

2005

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A Localized Surface Plasmon Resonance Biosensor: First Steps toward an Assay for Alzheimer's Disease

Nano letters, 2004-06, Vol.4 (6), p.1029-1034

2004

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Alzheimer's Disease-Affected Brain: Presence of Oligomeric Aβ Ligands (ADDLs) Suggests a Molecular Basis for Reversible Memory Loss

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (18), p.10417-10422

2003

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Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis

Acta neuropathologica, 2015-02, Vol.129 (2), p.183-206

2015

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Nanoparticle-Based Detection in Cerebral Spinal Fluid of a Soluble Pathogenic Biomarker for Alzheimer's Disease

Proceedings of the National Academy of Sciences - PNAS, 2005-02, Vol.102 (7), p.2273-2276

2005

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Amyloid Beta Oligomers Target to Extracellular and Intracellular Neuronal Synaptic Proteins in Alzheimer's Disease

Frontiers in neurology, 2019-11, Vol.10, p.1140-1140

2019

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Synaptotoxic amyloid-β oligomers: a molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease?

Journal of Alzheimer's disease, 2013-01, Vol.33 Suppl 1, p.S49

Klein, William L

2013

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Antibody Fragments as Tools for Elucidating Structure-Toxicity Relationships and for Diagnostic/Therapeutic Targeting of Neurotoxic Amyloid Oligomers

International journal of molecular sciences, 2020-11, Vol.21 (23), p.8920

2020

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The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade

Journal of Alzheimer's disease, 2018-01, Vol.64 (s1), p.S567

2018

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Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1

The European journal of neuroscience, 2006-01, Vol.23 (1), p.251-260

2006

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An Essential Role for Alzheimer's-Linked Amyloid Beta Oligomers in Neurodevelopment: Transient Expression of Multiple Proteoforms during Retina Histogenesis

International journal of molecular sciences, 2022-02, Vol.23 (4), p.2208

2022

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The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer's Disease

Frontiers in neuroscience, 2022-01, Vol.15, p.768646-768646

2022

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The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease

Neurobiology of learning and memory, 2011-11, Vol.96 (4), p.529-543

2011

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Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers

PloS one, 2015-04, Vol.10 (4), p.e0125263

2015

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Amyloid-β triggers the release of neuronal hexokinase 1 from mitochondria

PloS one, 2010-12, Vol.5 (12), p.e15230

2010

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Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer's disease

Brain (London, England : 1878), 2015-06, Vol.138 (Pt 6), p.1722-1737

2015

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Diet‐induced Alzheimer's‐like syndrome in the rabbit

Alzheimer's & dementia : translational research & clinical interventions, 2022, Vol.8 (1), p.e12241-n/a

2022

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Deleterious Effects of Amyloid β Oligomers Acting as an Extracellular Scaffold for mGluR5

Neuron (Cambridge, Mass.), 2010-06, Vol.66 (5), p.739-754

2010

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Rifampicin is a candidate preventive medicine against amyloid-β and tau oligomers

Brain (London, England : 1878), 2016-05, Vol.139 (Pt 5), p.1568-1586

2016

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NLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer’s Disease

Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease

TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys

Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer’s pathology

Detection of a Biomarker for Alzheimer's Disease from Synthetic and Clinical Samples Using a Nanoscale Optical Biosensor

A Localized Surface Plasmon Resonance Biosensor: First Steps toward an Assay for Alzheimer's Disease

Alzheimer's Disease-Affected Brain: Presence of Oligomeric Aβ Ligands (ADDLs) Suggests a Molecular Basis for Reversible Memory Loss

Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis

Nanoparticle-Based Detection in Cerebral Spinal Fluid of a Soluble Pathogenic Biomarker for Alzheimer's Disease

Amyloid Beta Oligomers Target to Extracellular and Intracellular Neuronal Synaptic Proteins in Alzheimer's Disease

Synaptotoxic amyloid-β oligomers: a molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease?

Antibody Fragments as Tools for Elucidating Structure-Toxicity Relationships and for Diagnostic/Therapeutic Targeting of Neurotoxic Amyloid Oligomers

The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade

Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1

An Essential Role for Alzheimer's-Linked Amyloid Beta Oligomers in Neurodevelopment: Transient Expression of Multiple Proteoforms during Retina Histogenesis

The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer's Disease

The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease

Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aβ Oligomers

Amyloid-β triggers the release of neuronal hexokinase 1 from mitochondria

Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer's disease

Diet‐induced Alzheimer's‐like syndrome in the rabbit

Deleterious Effects of Amyloid β Oligomers Acting as an Extracellular Scaffold for mGluR5

Rifampicin is a candidate preventive medicine against amyloid-β and tau oligomers

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