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Epithelial-to-Mesenchymal Transition Defines Feedback Activation of Receptor Tyrosine Kinase Signaling Induced by MEK Inhibition in KRAS-Mutant Lung Cancer

Cancer discovery, 2016-07, Vol.6 (7), p.754-769

2016

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WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC

Cell reports (Cambridge), 2022-05, Vol.39 (7), p.110814-110814, Article 110814

2022

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Combined inhibition of KRASG12C and mTORC1 kinase is synergistic in non-small cell lung cancer

Nature communications, 2024-07, Vol.15 (1), p.6076-15, Article 6076

2024

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Resistance mediated by alternative receptor tyrosine kinases in FGFR1-amplified lung cancer

Carcinogenesis (New York), 2017-10, Vol.38 (11), p.1063-1072

2017

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Reduction of background carrier concentration and lifetime improvement for 4H-SiC C-face epitaxial growth

Japanese Journal of Applied Physics, 2017-08, Vol.56 (8), p.81302

2017

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Oncogene alterations in non-small cell lung cancer with FGFR1 amplification—novel approach to stratify patients who benefit from FGFR inhibitors

Translational lung cancer research, 2024-03, Vol.13 (3), p.684-688

2024

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Analysis of Gate Oxide Nitridation Effect on SiC MOSFETs by Using Hall Measurement and Split C–V Measurement

Materials Science Forum, 2016-05, Vol.858, p.441-444

2016

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Electrical and physical characterizations of the effects of oxynitridation and wet oxidation at the interface of SiO2/4H-SiC(0001) and

Japanese Journal of Applied Physics, 2016-03, Vol.55 (4S)

2016

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Systematic Investigation of 4H-SiC Trench Properties Dependence on Channel Concentration, Crystallographic Plane, and MOS Interface Treatment

Materials Science Forum, 2016-05, Vol.858, p.639-642

2016

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Improvements of visual function and outer retinal morphology following spontaneous regression of cancer in anti-recoverin cancer-associated retinopathy

American journal of ophthalmology case reports, 2017-04, Vol.5 (C), p.137-140

2017

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Key roles of EMT for adaptive resistance to MEK inhibitor in KRAS mutant lung cancer

Small GTPases, 2017-07, Vol.8 (3), p.172-176

2017

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A superior 15 kV SiC MOSFET with current spreading layer for high-frequency applications

Japanese Journal of Applied Physics, 2019-04, Vol.58 (SB), p.SBBD16

2019

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Inhibition of non-homologous end joining mitigates paclitaxel resistance resulting from mitotic slippage in non-small cell lung cancer

Cell cycle (Georgetown, Tex.), 2023-09, Vol.22 (17), p.1854-1864

2023

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Abstract 2086: Dominant role of receptor tyrosine kinase in the activation of MAPK signaling in BRAF non-V600 mutant cancers

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.2086-2086

2017

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Distinct dependencies on receptor tyrosine kinases in the regulation of MAPK signaling between BRAF V600E and non-V600E mutant lung cancers

Oncogene, 2018-03, Vol.37 (13), p.1775-1787

2018

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Response to Crizotinib Re-administration After Progression on Lorlatinib in a Patient With ALK-rearranged Non–small-cell Lung Cancer

Clinical lung cancer, 2019-09, Vol.20 (5), p.e555-e559

2019

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Response of BRAFV600E-Mutant Lung Adenocarcinoma With Brain Metastasis and Leptomeningeal Dissemination to Dabrafenib Plus Trametinib Treatment

Journal of thoracic oncology, 2019-05, Vol.14 (5), p.e97-e99

2019

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Development of a novel 1200-V-class 4H-SiC implantation-and-epitaxial trench MOSFET with low on-resistance

Japanese Journal of Applied Physics, 2016-04, Vol.55 (4S), p.4

2016

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1200 V SiC IE-UMOSFET with low on-resistance and high threshold voltage

2016 European Conference on Silicon Carbide & Related Materials (ECSCRM), 2017-05, Vol.897, p.1-1

2017

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The bi-steric mTORC1-selective inhibitor RMC-5552 in tumors with activation of mTOR signaling: Preclinical activity in combination with RAS(ON) inhibitors in RAS-addicted tumors, and initial clinical findings from a single agent phase 1/1b study

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.3098-3098

2022

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Development of a Pulsed Power Supply Utilizing 13 kV Class SiC-MOSFETs

Materials science forum, 2020-07, Vol.1004, p.1141-1147

2020

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Response to First-Line Osimertinib Treatment in Non–Small-Cell Lung Cancer With Coexisting G719A and Primary T790M Epidermal Growth Factor Receptor Mutations

Clinical lung cancer, 2019-07, Vol.20 (4), p.e531-e533

2019

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Carrier Lifetimes in 4H-SiC Epitaxial Layers on the C-Face Enhanced by Carbon Implantation

Materials science forum, 2018-06, Vol.924, p.432-435

2018

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Demonstration of 13-kV class junction barrier Schottky diodes in 4H-SiC with three-zone junction termination extension

2016 European Conference on Silicon Carbide & Related Materials (ECSCRM), 2017-05, Vol.897, p.1-1

2017

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Epithelial-to-Mesenchymal Transition Defines Feedback Activation of Receptor Tyrosine Kinase Signaling Induced by MEK Inhibition in KRAS-Mutant Lung Cancer

WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC

Combined inhibition of KRASG12C and mTORC1 kinase is synergistic in non-small cell lung cancer

Epithelial-to-Mesenchymal Transition Antagonizes Response to Targeted Therapies in Lung Cancer by Suppressing BIM

Resistance mediated by alternative receptor tyrosine kinases in FGFR1-amplified lung cancer

Reduction of background carrier concentration and lifetime improvement for 4H-SiC C-face epitaxial growth

Oncogene alterations in non-small cell lung cancer with FGFR1 amplification—novel approach to stratify patients who benefit from FGFR inhibitors

Analysis of Gate Oxide Nitridation Effect on SiC MOSFETs by Using Hall Measurement and Split C–V Measurement

Electrical and physical characterizations of the effects of oxynitridation and wet oxidation at the interface of SiO2/4H-SiC(0001) and

Systematic Investigation of 4H-SiC Trench Properties Dependence on Channel Concentration, Crystallographic Plane, and MOS Interface Treatment

Improvements of visual function and outer retinal morphology following spontaneous regression of cancer in anti-recoverin cancer-associated retinopathy

Key roles of EMT for adaptive resistance to MEK inhibitor in KRAS mutant lung cancer

A superior 15 kV SiC MOSFET with current spreading layer for high-frequency applications

Inhibition of non-homologous end joining mitigates paclitaxel resistance resulting from mitotic slippage in non-small cell lung cancer

Abstract 2086: Dominant role of receptor tyrosine kinase in the activation of MAPK signaling in BRAF non-V600 mutant cancers

Distinct dependencies on receptor tyrosine kinases in the regulation of MAPK signaling between BRAF V600E and non-V600E mutant lung cancers

Response to Crizotinib Re-administration After Progression on Lorlatinib in a Patient With ALK-rearranged Non–small-cell Lung Cancer

Response of BRAFV600E-Mutant Lung Adenocarcinoma With Brain Metastasis and Leptomeningeal Dissemination to Dabrafenib Plus Trametinib Treatment

Development of a novel 1200-V-class 4H-SiC implantation-and-epitaxial trench MOSFET with low on-resistance

1200 V SiC IE-UMOSFET with low on-resistance and high threshold voltage

The bi-steric mTORC1-selective inhibitor RMC-5552 in tumors with activation of mTOR signaling: Preclinical activity in combination with RAS(ON) inhibitors in RAS-addicted tumors, and initial clinical findings from a single agent phase 1/1b study

Development of a Pulsed Power Supply Utilizing 13 kV Class SiC-MOSFETs

Response to First-Line Osimertinib Treatment in Non–Small-Cell Lung Cancer With Coexisting G719A and Primary T790M Epidermal Growth Factor Receptor Mutations

Carrier Lifetimes in 4H-SiC Epitaxial Layers on the C-Face Enhanced by Carbon Implantation

Demonstration of 13-kV class junction barrier Schottky diodes in 4H-SiC with three-zone junction termination extension

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