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A phase IB trial of 24-hour intravenous PX-12, a thioredoxin-1 inhibitor, in patients with advanced gastrointestinal cancers

Investigational new drugs, 2013-06, Vol.31 (3), p.631-641

2013

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Utilization of distillers dried grains with solubles and phytase in sow lactation diets to meet the phosphorus requirement of the sow and reduce fecal phosphorus concentration

Journal of animal science, 2008-01, Vol.86 (1), p.112

2008

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Mechanisms of Inhibition of the Thioredoxin Growth Factor System by Antitumor 2-Imidazolyl Disulfides

Biochemical pharmacology, 1998-04, Vol.55 (7), p.987-994

1998

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Transgenic Overexpression of Constitutively Active Protein Kinase C ε Causes Concentric Cardiac Hypertrophy

Circulation research, 2000-06, Vol.86 (12), p.1218-1223

2000

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Effects of total replacement of atrial myosin light chain-2 with the ventricular isoform in atrial myocytes of transgenic mice

Circulation (New York, N.Y.), 1998-04, Vol.97 (15), p.1508-1513

1998

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Disruption of a Single Copy of the SERCA2 Gene Results in Altered Ca2+ Homeostasis and Cardiomyocyte Function

The Journal of biological chemistry, 2000-12, Vol.275 (48), p.38073-38080

2000

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The thioredoxin/thioredoxin reductase redox system and control of cell growth

Oncology research, 1994, Vol.6 (10-11), p.539

1994

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Redox Control as a Target for Anticancer Drug Development

Current pharmaceutical design, 1997-06, Vol.3 (3), p.305-322

Kirkpatrick, D. L.

1997

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Utilization of distillers dried grains with solubles and phytase in sow lactation diets to meet the phosphorus requirement of the sow and reduce fecal phosphorus concentration1

Journal of animal science, 2008-01, Vol.86 (1), p.112-118

2008

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Thioredoxin redox control of cell growth and death and the effects of inhibitors

Chemico-biological interactions, 1998-04, Vol.111, p.23-34

1998

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Effect of angiotensin-converting enzyme inhibition on protein kinase C and SR proteins in heart failure

American journal of physiology. Heart and circulatory physiology, 1999-01, Vol.276 (1), p.H53-H62

1999

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Cell line-directed screening assay for inhibitors of thioredoxin reductase signaling as potential anti-cancer drugs

Anti-cancer drug design, 1997-12, Vol.12 (8), p.659

1997

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Parallel syntheses of disulfide inhibitors of the thioredoxin redox system as potential antitumor agents

Anti-cancer drug design, 1999-10, Vol.14 (5), p.421

1999

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Reversible inhibition of human thioredoxin reductase activity by cytotoxic alkyl 2-imidazolyl disulfide analogues

Cancer chemotherapy and pharmacology, 1994, Vol.34 (5), p.434-438

1994

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Disulfide cytotoxicity under hypoxia

Oncology research, 1994, Vol.6 (10-11), p.545

1994

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Structure-based drug design: combinatorial chemistry and molecular modeling

Combinatorial chemistry & high throughput screening, 1999-08, Vol.2 (4), p.211-221

1999

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C103 TOMORROW NEVER LIES: COPD EXACERBATION TREATMENT AND OUTCOMES: Predictors Of Readmission Due To Acute Exacerbation Of Chronic Obstructive Pulmonary Disease

American journal of respiratory and critical care medicine, 2014-01, Vol.189, p.1

2014

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Synthesis and Cytotoxic Evaluation of Some 6-Arylidene-2-(α-hydroxyamino-α-arylmethyl)cyclohexanone Oximes and Related Compounds

Journal of pharmaceutical sciences, 1992-11, Vol.81 (11), p.1059-1064

1992

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Nitrobenzyl derivatives as bioreductive alkylating agents: evidence for the reductive formation of a reactive intermediate

Journal of medicinal chemistry, 1986-10, Vol.29 (10), p.2048-2052

1986

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Modification of antitumor disulfide cytotoxicity by glutathione depletion in murine cells

Cancer research (Chicago, Ill.), 1987-08, Vol.47 (16), p.4391-4395

KIRKPATRICK, D. L

1987

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The phosphatidylinositol-3-kinase inhibitor PX-866 overcomes resistance to the epidermal growth factor receptor inhibitor gefitinib in A-549 human non–small cell lung cancer xenografts

Molecular cancer therapeutics, 2005-09, Vol.4 (9), p.1349-1357

2005

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Chemosensitivity testing of fresh human leukemia cells using both a dye exclusion assay and a tetrazolium dye (MTT) assay

Leukemia Research, 1990, Vol.14 (5), p.459-466

1990

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Selenium and the thioredoxin redox system: effects on cell growth and death

Oncology research, 1997, Vol.9 (6-7), p.303

1997

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Inhibitory effects of cytotoxic disulfides on membrane Na +,K +-ATPase

Biochemical pharmacology, 1990-05, Vol.39 (9), p.1484-1487

1990

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A phase IB trial of 24-hour intravenous PX-12, a thioredoxin-1 inhibitor, in patients with advanced gastrointestinal cancers

Utilization of distillers dried grains with solubles and phytase in sow lactation diets to meet the phosphorus requirement of the sow and reduce fecal phosphorus concentration

Mechanisms of Inhibition of the Thioredoxin Growth Factor System by Antitumor 2-Imidazolyl Disulfides

Transgenic Overexpression of Constitutively Active Protein Kinase C ε Causes Concentric Cardiac Hypertrophy

Effects of total replacement of atrial myosin light chain-2 with the ventricular isoform in atrial myocytes of transgenic mice

Disruption of a Single Copy of the SERCA2 Gene Results in Altered Ca2+ Homeostasis and Cardiomyocyte Function

The thioredoxin/thioredoxin reductase redox system and control of cell growth

Redox Control as a Target for Anticancer Drug Development

Utilization of distillers dried grains with solubles and phytase in sow lactation diets to meet the phosphorus requirement of the sow and reduce fecal phosphorus concentration1

Thioredoxin redox control of cell growth and death and the effects of inhibitors

Effect of angiotensin-converting enzyme inhibition on protein kinase C and SR proteins in heart failure

Cell line-directed screening assay for inhibitors of thioredoxin reductase signaling as potential anti-cancer drugs

Parallel syntheses of disulfide inhibitors of the thioredoxin redox system as potential antitumor agents

Reversible inhibition of human thioredoxin reductase activity by cytotoxic alkyl 2-imidazolyl disulfide analogues

Disulfide cytotoxicity under hypoxia

Structure-based drug design: combinatorial chemistry and molecular modeling

C103 TOMORROW NEVER LIES: COPD EXACERBATION TREATMENT AND OUTCOMES: Predictors Of Readmission Due To Acute Exacerbation Of Chronic Obstructive Pulmonary Disease

Synthesis and Cytotoxic Evaluation of Some 6-Arylidene-2-(α-hydroxyamino-α-arylmethyl)cyclohexanone Oximes and Related Compounds

Nitrobenzyl derivatives as bioreductive alkylating agents: evidence for the reductive formation of a reactive intermediate

Modification of antitumor disulfide cytotoxicity by glutathione depletion in murine cells

The phosphatidylinositol-3-kinase inhibitor PX-866 overcomes resistance to the epidermal growth factor receptor inhibitor gefitinib in A-549 human non–small cell lung cancer xenografts

Chemosensitivity testing of fresh human leukemia cells using both a dye exclusion assay and a tetrazolium dye (MTT) assay

Selenium and the thioredoxin redox system: effects on cell growth and death

Inhibitory effects of cytotoxic disulfides on membrane Na +,K +-ATPase

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