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Development of a genome-targeting mutator for the adaptive evolution of microbial cells

Nucleic acids research, 2022-04, Vol.50 (7), p.e38-e38

2022

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Reconstitution of Outer Membrane Protein Assembly from Purified Components

Science (American Association for the Advancement of Science), 2010-05, Vol.328 (5980), p.890-892

2010

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Bioinformatic Expansion of Borosins Uncovers Trans-Acting Peptide Backbone N‑Methyltransferases in Bacteria

Biochemistry (Easton), 2022-02, Vol.61 (3), p.183-194

2022

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Cage assembly of DegP protease is not required for substrate-dependent regulation of proteolytic activity or high-temperature cell survival

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (19), p.7263-7268

2012

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Verbenalin Reduces Amyloid-Beta Peptide Generation in Cellular and Animal Models of Alzheimer's Disease

Molecules (Basel, Switzerland), 2022-12, Vol.27 (24), p.8678

2022

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Molecular mechanism underlying substrate recognition of the peptide macrocyclase PsnB

Nature chemical biology, 2021-11, Vol.17 (11), p.1123-1131

2021

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Gene-specific mutagenesis enables rapid continuous evolution of enzymes in vivo

Nucleic acids research, 2021-04, Vol.49 (6), p.e32-e32

2021

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Structure and Function of an Essential Component of the Outer Membrane Protein Assembly Machine

Science (American Association for the Advancement of Science), 2007-08, Vol.317 (5840), p.961-964

2007

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Identification of a Multicomponent Complex Required for Outer Membrane Biogenesis in Escherichia coli

Cell, 2005-04, Vol.121 (2), p.235-245

2005

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Identification of Nucleophilic Probes for Protease-Mediated Transpeptidation

Molecules (Basel, Switzerland), 2018-08, Vol.23 (9), p.2109

2018

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YfiO stabilizes the YaeT complex and is essential for outer membrane protein assembly in Escherichia coli

Molecular microbiology, 2006-07, Vol.61 (1), p.151-164

2006

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Evolutionary Spread of Distinct O‐methyltransferases Guides the Discovery of Unique Isoaspartate‐Containing Peptides, Pamtides

Advanced science, 2024-01, Vol.11 (2), p.e2305946-n/a

2024

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A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases

Structure (London), 2015-03, Vol.23 (3), p.517-526

2015

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Enzymatic Cross-Linking of Side Chains Generates a Modified Peptide with Four Hairpin-like Bicyclic Repeats

Biochemistry (Easton), 2017-09, Vol.56 (37), p.4927-4930

2017

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A dual gene-specific mutator system installs all transition mutations at similar frequencies in vivo

Nucleic acids research, 2023-06, Vol.51 (10), p.e59-e59

2023

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A Topologically Distinct Modified Peptide with Multiple Bicyclic Core Motifs Expands the Diversity of Microviridin‐Like Peptides

Chembiochem : a European journal of chemical biology, 2019-04, Vol.20 (8), p.1051-1059

2019

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Genome Mining Reveals High Topological Diversity of ω‑Ester-Containing Peptides and Divergent Evolution of ATP-Grasp Macrocyclases

Journal of the American Chemical Society, 2020-02, Vol.142 (6), p.3013-3023

2020

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Introduction of Bifunctionality into the Multidomain Architecture of the ω‑Ester-Containing Peptide Plesiocin

Biochemistry (Easton), 2020-01, Vol.59 (3), p.285-289

2020

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A Small Periplasmic Protein with a Hydrophobic C-Terminal Residue Enhances DegP Proteolysis as a Suicide Activator

Journal of bacteriology, 2018-02, Vol.200 (3)

2018

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Exploring the Diverse Landscape of Biaryl-Containing Peptides Generated by Cytochrome P450 Macrocyclases

Journal of the American Chemical Society, 2023-10, Vol.145 (40), p.22047-22057

2023

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Discovery and Biosynthesis of Cihunamides, Macrocyclic Antibacterial RiPPs with a Unique C−N Linkage Formed by CYP450 Catalysis

Angewandte Chemie International Edition, 2023-06, Vol.62 (26), p.e202300998-n/a

International ed. in English, 2023

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A Small Periplasmic Protein with a Hydrophobic CTerminal Residue Enhances DegP Proteolysis as a Suicide Activator

Journal of bacteriology, 2018-02, Vol.200 (3)

2018

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Distinct regulatory mechanisms balance DegP proteolysis to maintain cellular fitness during heat stress

Genes & development, 2014-04, Vol.28 (8), p.902-911

2014

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Tripodal Lipoprotein Variants with C-Terminal Hydrophobic Residues Allosterically Modulate Activity of the DegP Protease

Journal of molecular biology, 2017-10, Vol.429 (20), p.3090-3101

2017

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Development of a genome-targeting mutator for the adaptive evolution of microbial cells

Reconstitution of Outer Membrane Protein Assembly from Purified Components

Bioinformatic Expansion of Borosins Uncovers Trans-Acting Peptide Backbone N‑Methyltransferases in Bacteria

Cage assembly of DegP protease is not required for substrate-dependent regulation of proteolytic activity or high-temperature cell survival

Verbenalin Reduces Amyloid-Beta Peptide Generation in Cellular and Animal Models of Alzheimer's Disease

Molecular mechanism underlying substrate recognition of the peptide macrocyclase PsnB

Gene-specific mutagenesis enables rapid continuous evolution of enzymes in vivo

Structure and Function of an Essential Component of the Outer Membrane Protein Assembly Machine

Identification of a Multicomponent Complex Required for Outer Membrane Biogenesis in Escherichia coli

Identification of Nucleophilic Probes for Protease-Mediated Transpeptidation

YfiO stabilizes the YaeT complex and is essential for outer membrane protein assembly in Escherichia coli

Evolutionary Spread of Distinct O‐methyltransferases Guides the Discovery of Unique Isoaspartate‐Containing Peptides, Pamtides

A Conserved Activation Cluster Is Required for Allosteric Communication in HtrA-Family Proteases

Enzymatic Cross-Linking of Side Chains Generates a Modified Peptide with Four Hairpin-like Bicyclic Repeats

A dual gene-specific mutator system installs all transition mutations at similar frequencies in vivo

A Topologically Distinct Modified Peptide with Multiple Bicyclic Core Motifs Expands the Diversity of Microviridin‐Like Peptides

Genome Mining Reveals High Topological Diversity of ω‑Ester-Containing Peptides and Divergent Evolution of ATP-Grasp Macrocyclases

Introduction of Bifunctionality into the Multidomain Architecture of the ω‑Ester-Containing Peptide Plesiocin

New developments in RiPP discovery, enzymology and engineering

A Small Periplasmic Protein with a Hydrophobic C-Terminal Residue Enhances DegP Proteolysis as a Suicide Activator

Exploring the Diverse Landscape of Biaryl-Containing Peptides Generated by Cytochrome P450 Macrocyclases

Discovery and Biosynthesis of Cihunamides, Macrocyclic Antibacterial RiPPs with a Unique C−N Linkage Formed by CYP450 Catalysis

A Small Periplasmic Protein with a Hydrophobic CTerminal Residue Enhances DegP Proteolysis as a Suicide Activator

Distinct regulatory mechanisms balance DegP proteolysis to maintain cellular fitness during heat stress

Tripodal Lipoprotein Variants with C-Terminal Hydrophobic Residues Allosterically Modulate Activity of the DegP Protease

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