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An autophagy enhancer ameliorates diabetes of human IAPP-transgenic mice through clearance of amyloidogenic oligomer

Nature communications, 2021-01, Vol.12 (1), p.183-183, Article 183

2021

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Prediction of the sequence-specific cleavage activity of Cas9 variants

Nature biotechnology, 2020-11, Vol.38 (11), p.1328-1336

2020

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Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia

American journal of human genetics, 2017-03, Vol.100 (3), p.454-472

2017

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Paired D10A Cas9 nickases are sometimes more efficient than individual nucleases for gene disruption

Nucleic acids research, 2018-07, Vol.46 (12), p.e71-e71

2018

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Sequence-specific prediction of the efficiencies of adenine and cytosine base editors

Nature biotechnology, 2020-09, Vol.38 (9), p.1037-1043

2020

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Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination

Neuron (Cambridge, Mass.), 2018-07, Vol.99 (1), p.83-97.e7

2018

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Generation of a more efficient prime editor 2 by addition of the Rad51 DNA-binding domain

Nature communications, 2021-09, Vol.12 (1), p.5617-5617, Article 5617

2021

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Concise Review: Fate Determination of Stem Cells by Deubiquitinating Enzymes

Stem cells (Dayton, Ohio), 2017-01, Vol.35 (1), p.9-16

2017

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High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells

Nature biomedical engineering, 2020-01, Vol.4 (1), p.111-124

2020

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Deep learning improves prediction of CRISPR-Cpf1 guide RNA activity

Nature biotechnology, 2018-03, Vol.36 (3), p.239-241

2018

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Astroglial Activation by an Enriched Environment after Transplantation of Mesenchymal Stem Cells Enhances Angiogenesis after Hypoxic-Ischemic Brain Injury

International journal of molecular sciences, 2016-09, Vol.17 (9), p.1550-1550

2016

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Improving CRISPR tools by elucidating DNA repair

Nature biotechnology, 2021-12, Vol.39 (12), p.1512-1514

2021

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Targeted Genome Engineering to Control VEGF Expression in Human Umbilical Cord Blood‐Derived Mesenchymal Stem Cells: Potential Implications for the Treatment of Myocardial Infarction

Stem cells translational medicine, 2017-03, Vol.6 (3), p.1040-1051

2017

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Generation of mutation-corrected induced pluripotent stem cell lines derived from adrenoleukodystrophy patient by using homology directed repair

Stem cell research, 2022-03, Vol.59, p.102664-102664, Article 102664

2022

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SynDesign: web-based prime editing guide RNA design and evaluation tool for saturation genome editing

Nucleic acids research, 2024-07, Vol.52 (W1), p.W121-W125

2024

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Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth

Genome research, 2018-03, Vol.28 (3), p.374-382

2018

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Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer

Cell death and differentiation, 2020-11, Vol.27 (11), p.3004-3020

2020

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Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases

Nature biomedical engineering, 2022-02, Vol.6 (2), p.181-194

2022

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RanBPM: a potential therapeutic target for modulating diverse physiological disorders

Drug discovery today, 2017-12, Vol.22 (12), p.1816-1824

2017

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LIN28A loss of function is associated with Parkinson's disease pathogenesis

The EMBO journal, 2019-12, Vol.38 (24), p.e101196-n/a

2019

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DNA double-strand break-free CRISPR interference delays Huntington's disease progression in mice

Communications biology, 2023-04, Vol.6 (1), p.466-466, Article 466

2023

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Predicting the efficiency of prime editing guide RNAs in human cells

Nature biotechnology, 2021-02, Vol.39 (2), p.198-206

2021

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Hyongbum (Henry) Kim

Nature methods, 2017-02, Vol.14 (2), p.99-99

2017

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Prediction of efficiencies for diverse prime editing systems in multiple cell types

Cell, 2023-05, Vol.186 (10), p.2256-2272.e23

2023

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Programmable Nuclease-Based Integration into Novel Extragenic Genomic Safe Harbor Identified from Korean Population-Based CNV Analysis

Molecular therapy. Oncolytics, 2019-09, Vol.14, p.253-265

2019

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An autophagy enhancer ameliorates diabetes of human IAPP-transgenic mice through clearance of amyloidogenic oligomer

Prediction of the sequence-specific cleavage activity of Cas9 variants

Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia

Paired D10A Cas9 nickases are sometimes more efficient than individual nucleases for gene disruption

Sequence-specific prediction of the efficiencies of adenine and cytosine base editors

Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination

Generation of a more efficient prime editor 2 by addition of the Rad51 DNA-binding domain

Concise Review: Fate Determination of Stem Cells by Deubiquitinating Enzymes

High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells

Deep learning improves prediction of CRISPR-Cpf1 guide RNA activity

Astroglial Activation by an Enriched Environment after Transplantation of Mesenchymal Stem Cells Enhances Angiogenesis after Hypoxic-Ischemic Brain Injury

Improving CRISPR tools by elucidating DNA repair

Targeted Genome Engineering to Control VEGF Expression in Human Umbilical Cord Blood‐Derived Mesenchymal Stem Cells: Potential Implications for the Treatment of Myocardial Infarction

Generation of mutation-corrected induced pluripotent stem cell lines derived from adrenoleukodystrophy patient by using homology directed repair

SynDesign: web-based prime editing guide RNA design and evaluation tool for saturation genome editing

Targeting mutant KRAS with CRISPR-Cas9 controls tumor growth

Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer

Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases

RanBPM: a potential therapeutic target for modulating diverse physiological disorders

LIN28A loss of function is associated with Parkinson's disease pathogenesis

DNA double-strand break-free CRISPR interference delays Huntington's disease progression in mice

Predicting the efficiency of prime editing guide RNAs in human cells

Hyongbum (Henry) Kim

Prediction of efficiencies for diverse prime editing systems in multiple cell types

Programmable Nuclease-Based Integration into Novel Extragenic Genomic Safe Harbor Identified from Korean Population-Based CNV Analysis

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