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An autophagy enhancer ameliorates diabetes of human IAPP-transgenic mice through clearance of amyloidogenic oligomer

Nature communications, 2021-01, Vol.12 (1), p.183-183, Article 183

2021

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Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia

American journal of human genetics, 2017-03, Vol.100 (3), p.454-472

2017

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Prediction of the sequence-specific cleavage activity of Cas9 variants

Nature biotechnology, 2020-11, Vol.38 (11), p.1328-1336

2020

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Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination

Neuron (Cambridge, Mass.), 2018-07, Vol.99 (1), p.83-97.e7

2018

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Sequence-specific prediction of the efficiencies of adenine and cytosine base editors

Nature biotechnology, 2020-09, Vol.38 (9), p.1037-1043

2020

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Generation of a more efficient prime editor 2 by addition of the Rad51 DNA-binding domain

Nature communications, 2021-09, Vol.12 (1), p.5617-5617, Article 5617

2021

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Concise Review: Fate Determination of Stem Cells by Deubiquitinating Enzymes

Stem cells (Dayton, Ohio), 2017-01, Vol.35 (1), p.9-16

2017

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High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells

Nature biomedical engineering, 2020-01, Vol.4 (1), p.111

2020

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Astroglial Activation by an Enriched Environment after Transplantation of Mesenchymal Stem Cells Enhances Angiogenesis after Hypoxic-Ischemic Brain Injury

International journal of molecular sciences, 2016-09, Vol.17 (9), p.1550-1550

2016

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Deep learning improves prediction of CRISPR-Cpf1 guide RNA activity

Nature biotechnology, 2018-03, Vol.36 (3), p.239-241

2018

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Predicting the efficiency of prime editing guide RNAs in human cells

Nature biotechnology, 2021-02, Vol.39 (2), p.198-206

2021

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Improving CRISPR tools by elucidating DNA repair

Nature biotechnology, 2021-12, Vol.39 (12), p.1512-1514

2021

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Targeted Genome Engineering to Control VEGF Expression in Human Umbilical Cord Blood‐Derived Mesenchymal Stem Cells: Potential Implications for the Treatment of Myocardial Infarction

Stem cells translational medicine, 2017-03, Vol.6 (3), p.1040-1051

2017

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Generation of mutation-corrected induced pluripotent stem cell lines derived from adrenoleukodystrophy patient by using homology directed repair

Stem cell research, 2022-03, Vol.59, p.102664-102664, Article 102664

2022

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Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer

Cell death and differentiation, 2020-11, Vol.27 (11), p.3004-3020

2020

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Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases

Nature biomedical engineering, 2022-02, Vol.6 (2), p.181

2022

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RanBPM: a potential therapeutic target for modulating diverse physiological disorders

Drug discovery today, 2017-12, Vol.22 (12), p.1816-1824

2017

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LIN28A loss of function is associated with Parkinson's disease pathogenesis

The EMBO journal, 2019-12, Vol.38 (24), p.e101196-n/a

2019

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In Situ Pluripotency Factor Expression Promotes Functional Recovery From Cerebral Ischemia

Molecular therapy, 2016-09, Vol.24 (9), p.1538-1549

2016

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DNA double-strand break-free CRISPR interference delays Huntington's disease progression in mice

Communications biology, 2023-04, Vol.6 (1), p.466-466, Article 466

2023

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Programmable Nuclease-Based Integration into Novel Extragenic Genomic Safe Harbor Identified from Korean Population-Based CNV Analysis

Molecular therapy. Oncolytics, 2019-09, Vol.14, p.253-265

2019

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Prediction of efficiencies for diverse prime editing systems in multiple cell types

Cell, 2023-05, Vol.186 (10), p.2256-2272.e23

2023

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Author Correction: Predicting the efficiency of prime editing guide RNAs in human cells

Nature biotechnology, 2024-03, Vol.42 (3), p.529-529

2024

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Basic Principles and Clinical Applications of CRISPR-Based Genome Editing

Yonsei Medical Journal, 2022, 63(2), , pp.105-113

2022

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High-throughput functional evaluation of human cancer-associated mutations using base editors

Nature biotechnology, 2022-06, Vol.40 (6), p.874-884

2022

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An autophagy enhancer ameliorates diabetes of human IAPP-transgenic mice through clearance of amyloidogenic oligomer

Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia

Prediction of the sequence-specific cleavage activity of Cas9 variants

Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination

Sequence-specific prediction of the efficiencies of adenine and cytosine base editors

Generation of a more efficient prime editor 2 by addition of the Rad51 DNA-binding domain

Concise Review: Fate Determination of Stem Cells by Deubiquitinating Enzymes

High-throughput analysis of the activities of xCas9, SpCas9-NG and SpCas9 at matched and mismatched target sequences in human cells

Astroglial Activation by an Enriched Environment after Transplantation of Mesenchymal Stem Cells Enhances Angiogenesis after Hypoxic-Ischemic Brain Injury

Deep learning improves prediction of CRISPR-Cpf1 guide RNA activity

Predicting the efficiency of prime editing guide RNAs in human cells

Improving CRISPR tools by elucidating DNA repair

Targeted Genome Engineering to Control VEGF Expression in Human Umbilical Cord Blood‐Derived Mesenchymal Stem Cells: Potential Implications for the Treatment of Myocardial Infarction

Generation of mutation-corrected induced pluripotent stem cell lines derived from adrenoleukodystrophy patient by using homology directed repair

Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer

Application of prime editing to the correction of mutations and phenotypes in adult mice with liver and eye diseases

RanBPM: a potential therapeutic target for modulating diverse physiological disorders

LIN28A loss of function is associated with Parkinson's disease pathogenesis

In Situ Pluripotency Factor Expression Promotes Functional Recovery From Cerebral Ischemia

DNA double-strand break-free CRISPR interference delays Huntington's disease progression in mice

Programmable Nuclease-Based Integration into Novel Extragenic Genomic Safe Harbor Identified from Korean Population-Based CNV Analysis

Prediction of efficiencies for diverse prime editing systems in multiple cell types

Author Correction: Predicting the efficiency of prime editing guide RNAs in human cells

Basic Principles and Clinical Applications of CRISPR-Based Genome Editing

High-throughput functional evaluation of human cancer-associated mutations using base editors

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