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Structures and mechanisms of CRISPR RNA-guided effector nucleases

Current opinion in structural biology, 2017-04, Vol.43, p.68-78

2017

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Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9

Molecular cell, 2016-03, Vol.61 (6), p.886-894

2016

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Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1

Molecular cell, 2017-08, Vol.67 (4), p.633-645.e3

2017

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Engineered CRISPR-Cas9 nuclease with expanded targeting space

Science (American Association for the Advancement of Science), 2018-09, Vol.361 (6408), p.1259-1262

2018

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Generation of a more efficient prime editor 2 by addition of the Rad51 DNA-binding domain

Nature communications, 2021-09, Vol.12 (1), p.5617-5617, Article 5617

2021

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Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1

Nature communications, 2018-10, Vol.9 (1), p.4424-8, Article 4424

2018

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Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1

Molecular cell, 2017-07, Vol.67 (1), p.139-147.e2

2017

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Base editors for simultaneous introduction of C-to-T and A-to-G mutations

Nature biotechnology, 2020-07, Vol.38 (7), p.865-869

2020

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Structure of the miniature type V-F CRISPR-Cas effector enzyme

Molecular cell, 2021-02, Vol.81 (3), p.558-570.e3

2021

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Amplification-free RNA detection with CRISPR-Cas13

Communications biology, 2021-04, Vol.4 (1), p.476-476, Article 476

2021

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Real-space and real-time dynamics of CRISPR-Cas9 visualized by high-speed atomic force microscopy

Nature communications, 2017-11, Vol.8 (1), p.1430-9, Article 1430

2017

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Structure and Engineering of Francisella novicida Cas9

Cell, 2016-02, Vol.164 (5), p.950-961

2016

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Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex

Nature (London), 2022-07, Vol.607 (7918), p.393-398

2022

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Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9

Nature communications, 2019-04, Vol.10 (1), p.1968-1968, Article 1968

2019

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Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex

Cell, 2022-06, Vol.185 (13), p.2324-2337.e16

2022

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Crystal structure of Drosophila Piwi

Nature communications, 2020-02, Vol.11 (1), p.858-858, Article 858

2020

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Structure and function of Zucchini endoribonuclease in piRNA biogenesis

Nature (London), 2012-11, Vol.491 (7423), p.284-287

2012

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Crystal Structure of Silkworm PIWI-Clade Argonaute Siwi Bound to piRNA

Cell, 2016-10, Vol.167 (2), p.484-497.e9

2016

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Crystal structure of the plant receptor-like kinase TDR in complex with the TDIF peptide

Nature communications, 2016-08, Vol.7 (1), p.12383-12383, Article 12383

2016

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RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease

Science (American Association for the Advancement of Science), 2022-11, Vol.378 (6622), p.882-889

2022

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Dynamics of Target DNA Binding and Cleavage by Staphylococcus aureus Cas9 as Revealed by High-Speed Atomic Force Microscopy

ACS nano, 2023-03, Vol.17 (5), p.4629-4641

2023

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Real‐time observation of flexible domain movements in CRISPR–Cas9

The EMBO journal, 2018-05, Vol.37 (10), p.n/a

2018

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Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (42), p.16876-16881

2012

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Structure and engineering of the minimal type VI CRISPR-Cas13bt3

Molecular cell, 2022-09, Vol.82 (17), p.3178-3192.e5

2022

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Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization

Nature communications, 2016-07, Vol.7 (1), p.12198-12198, Article 12198

2016

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Structures and mechanisms of CRISPR RNA-guided effector nucleases

Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9

Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1

Engineered CRISPR-Cas9 nuclease with expanded targeting space

Generation of a more efficient prime editor 2 by addition of the Rad51 DNA-binding domain

Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1

Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1

Base editors for simultaneous introduction of C-to-T and A-to-G mutations

Structure of the miniature type V-F CRISPR-Cas effector enzyme

Amplification-free RNA detection with CRISPR-Cas13

Real-space and real-time dynamics of CRISPR-Cas9 visualized by high-speed atomic force microscopy

Structure and Engineering of Francisella novicida Cas9

Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex

Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9

Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex

Crystal structure of Drosophila Piwi

Structure and function of Zucchini endoribonuclease in piRNA biogenesis

Crystal Structure of Silkworm PIWI-Clade Argonaute Siwi Bound to piRNA

Crystal structure of the plant receptor-like kinase TDR in complex with the TDIF peptide

RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease

Dynamics of Target DNA Binding and Cleavage by Staphylococcus aureus Cas9 as Revealed by High-Speed Atomic Force Microscopy

Real‐time observation of flexible domain movements in CRISPR–Cas9

Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling

Structure and engineering of the minimal type VI CRISPR-Cas13bt3

Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization

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