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Progress and problems with the use of viral vectors for gene therapy

Nature reviews. Genetics, 2003-05, Vol.4 (5), p.346-358

2003

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World Health Organization International Standard to harmonize assays for detection of hepatitis E virus RNA

Emerging infectious diseases, 2013-05, Vol.19 (5), p.729-735

2013

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Robust expansion of human hepatocytes in Fah −/− / Rag2 −/− / Il2rg −/− mice

Nature biotechnology, 2007-08, Vol.25 (8), p.903-910

2007

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Helicobacter pylori resistance to antibiotics before and after treatment: Incidence of eradication failure

PloS one, 2022-04, Vol.17 (4), p.e0265322-e0265322

2022

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Therapeutic application of RNAi: is mRNA targeting finally ready for prime time?

The Journal of clinical investigation, 2007-12, Vol.117 (12), p.3633-3641

2007

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Combinatorial RNAi: A Winning Strategy for the Race Against Evolving Targets?

Molecular therapy, 2007-05, Vol.15 (5), p.878-888

2007

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Clinical characterization of Helicobacter pylori infected patients 15 years after unsuccessful eradication

PloS one, 2020-09, Vol.15 (9), p.e0238944-e0238944

2020

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TGN1412 Induces Lymphopenia and Human Cytokine Release in a Humanized Mouse Model

PloS one, 2016-03, Vol.11 (3), p.e0149093-e0149093

2016

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Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

Nature medicine, 2001-01, Vol.7 (1), p.33-40

2001

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From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy

Current gene therapy, 2003-08, Vol.3 (4), p.281-304

2003

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Prediction of long-term remission in patients following discontinuation of anti-TNF therapy in ulcerative colitis: a 10 year follow up study

BMC gastroenterology, 2022-11, Vol.22 (1), p.459-9, Article 459

2022

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Pharmacodynamic mechanisms behind a refractory state in inflammatory bowel disease

BMC gastroenterology, 2022-11, Vol.22 (1), p.1-464, Article 464

2022

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APOBEC4 Enhances the Replication of HIV-1

PloS one, 2016-06, Vol.11 (6), p.e0155422-e0155422

2016

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Gene expression RNA interference in adult mice

Nature (London), 2002-07, Vol.418 (6893), p.38-39

2002

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Inhibition of hepatitis B virus in mice by RNA interference

Nature biotechnology, 2003-06, Vol.21 (6), p.639-644

2003

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In vivo activity of nuclease-resistant siRNAs

RNA (Cambridge), 2004-05, Vol.10 (5), p.766-771

2004

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High-Resolution Genome-Wide Mapping of Transposon Integration in Mammals

Molecular and Cellular Biology, 2005-03, Vol.25 (6), p.2085-2094

2005

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RNA interference in adult mice

Nature (London), 2002-07, Vol.418 (6893), p.38-39

2002

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Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6

Molecular therapy, 2003-06, Vol.7 (6), p.839-850

2003

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Unrestricted Hepatocyte Transduction with Adeno-Associated Virus Serotype 8 Vectors in Mice

Journal of Virology, 2005-01, Vol.79 (1), p.214-224

2005

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Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo

Molecular therapy, 2003-09, Vol.8 (3), p.495-500

2003

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Rapid Uncoating of Vector Genomes Is the Key to Efficient Liver Transduction with Pseudotyped Adeno-Associated Virus Vectors

Journal of Virology, 2004-03, Vol.78 (6), p.3110-3122

2004

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AAV serotype 2 vectors preferentially integrate into active genes in mice

Nature genetics, 2003-07, Vol.34 (3), p.297-302

2003

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Discovery and validation of mucosal TNF expression combined with histological score - a biomarker for personalized treatment in ulcerative colitis

BMC gastroenterology, 2020-10, Vol.20 (1), p.321-321, Article 321

2020

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Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system

Nature genetics, 2000-05, Vol.25 (1), p.35-41

2000

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Progress and problems with the use of viral vectors for gene therapy

World Health Organization International Standard to harmonize assays for detection of hepatitis E virus RNA

Robust expansion of human hepatocytes in Fah −/− / Rag2 −/− / Il2rg −/− mice

Helicobacter pylori resistance to antibiotics before and after treatment: Incidence of eradication failure

Therapeutic application of RNAi: is mRNA targeting finally ready for prime time?

Combinatorial RNAi: A Winning Strategy for the Race Against Evolving Targets?

Clinical characterization of Helicobacter pylori infected patients 15 years after unsuccessful eradication

TGN1412 Induces Lymphopenia and Human Cytokine Release in a Humanized Mouse Model

Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

From virus evolution to vector revolution: use of naturally occurring serotypes of adeno-associated virus (AAV) as novel vectors for human gene therapy

Prediction of long-term remission in patients following discontinuation of anti-TNF therapy in ulcerative colitis: a 10 year follow up study

Pharmacodynamic mechanisms behind a refractory state in inflammatory bowel disease

APOBEC4 Enhances the Replication of HIV-1

Gene expression RNA interference in adult mice

Inhibition of hepatitis B virus in mice by RNA interference

In vivo activity of nuclease-resistant siRNAs

High-Resolution Genome-Wide Mapping of Transposon Integration in Mammals

RNA interference in adult mice

Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6

Unrestricted Hepatocyte Transduction with Adeno-Associated Virus Serotype 8 Vectors in Mice

Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo

Rapid Uncoating of Vector Genomes Is the Key to Efficient Liver Transduction with Pseudotyped Adeno-Associated Virus Vectors

AAV serotype 2 vectors preferentially integrate into active genes in mice

Discovery and validation of mucosal TNF expression combined with histological score - a biomarker for personalized treatment in ulcerative colitis

Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system

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