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Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (29), p.11788-11793

2012

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Design of Libraries Targeting Protein-Protein Interfaces

ChemMedChem, 2013-05, Vol.8 (5), p.726-732

2013

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Allosteric antibody inhibition of human hepsin protease

Biochemical journal, 2012-03, Vol.442 (3), p.483-494

2012

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A Selective Phosphatase of Regenerating Liver Phosphatase Inhibitor Suppresses Tumor Cell Anchorage-Independent Growth by a Novel Mechanism Involving p130Cas Cleavage

Cancer research (Chicago, Ill.), 2008-02, Vol.68 (4), p.1162-1169

2008

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Biosensor-based small molecule fragment screening with biolayer interferometry

Journal of computer-aided molecular design, 2011-07, Vol.25 (7), p.669-676

2011

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Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target

Science translational medicine, 2023-03, Vol.15 (686), p.eadc9249

2023

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Design and synthesis of 2-N-substituted indazolone derivatives as non-carboxylic acid glycogen synthase activators

Bioorganic & medicinal chemistry letters, 2013-05, Vol.23 (10), p.2936-2940

2013

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Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains

Nature (London), 1994-02, Vol.367 (6463), p.532-538

1994

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High‐Throughput Screening for Inhibitors of the Cks1–Skp2 Interaction

Methods in Enzymology, 2005, Vol.399, p.717-728

2005

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Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization

Science advances, 2020-05, Vol.6 (20), p.eaay1057-eaay1057

2020

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Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors

ACS medicinal chemistry letters, 2015-09, Vol.6 (9), p.1019-1024

2015

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Introducing Bayesian thinking to high-throughput screening for false-negative rate estimation

Journal of biomolecular screening, 2013-10, Vol.18 (9), p.1121-1131

2013

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High‐Throughput Measurements of Biochemical Responses Using the Plate::Vision Multimode 96 Minilens Array Reader

Measuring Biological Responses with Automated Microscopy, 2006, Vol.414, p.589-600

2006

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A homogeneous fluorescence polarization assay adaptable for a range of protein serine/threonine and tyrosine kinases

Journal of biomolecular screening, 2003-04, Vol.8 (2), p.164-175

2003

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Kinetic measurements of cell surface E-selectin/carbohydrate ligand interactions

Annals of biomedical engineering, 2001-11, Vol.29 (11), p.935-946

2001

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N-substituted sultam carboxylic acids as novel glycogen synthase activators

MedChemComm, 2013-05, Vol.4 (5), p.833-838

2013

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Decomposition of Acid Dye by TiO2 Thin Films Prepared by the Sol−Gel Method

Industrial & engineering chemistry research, 2006-03, Vol.45 (6), p.2040-2045

2006

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Primary Structure and Functional Activity of a Phosphatidylinositol-Glycan Specific Phospholipase D

Science (American Association for the Advancement of Science), 1991-04, Vol.252 (5004), p.446-448

1991

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High-throughput methods for measuring heparanase activity and screening potential antimetastatic and anti-inflammatory agents

Analytical biochemistry, 2004-10, Vol.333 (2), p.389-398

2004

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Protein-protein interactions involved in the recognition of p27 by E3 ubiquitin ligase

Biochemical journal, 2003-05, Vol.371 (Pt 3), p.957-964

2003

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[56] Glycosylphosphatidylinositol-specific phospholipase D

Methods in Enzymology, 1991, Vol.197, p.567-575

1991

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Abstract LB006: PC14586: The first orally bioavailable small molecule reactivator of Y220C mutant p53 in clinical development

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.LB006-LB006

2021

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Five distinct calcium and phospholipid binding proteins share homology with lipocortin I

The Journal of biological chemistry, 1988-08, Vol.263 (22), p.10799-10811

1988

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Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization

Design of Libraries Targeting Protein-Protein Interfaces

Allosteric antibody inhibition of human hepsin protease

A Selective Phosphatase of Regenerating Liver Phosphatase Inhibitor Suppresses Tumor Cell Anchorage-Independent Growth by a Novel Mechanism Involving p130Cas Cleavage

Discovery of 2‑[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia

Biosensor-based small molecule fragment screening with biolayer interferometry

Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target

Design and synthesis of 2-N-substituted indazolone derivatives as non-carboxylic acid glycogen synthase activators

Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains

High‐Throughput Screening for Inhibitors of the Cks1–Skp2 Interaction

Discovery of Orally Active Carboxylic Acid Derivatives of 2-Phenyl-5-trifluoromethyloxazole-4-carboxamide as Potent Diacylglycerol Acyltransferase-1 Inhibitors for the Potential Treatment of Obesity and Diabetes

Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization

Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors

Introducing Bayesian thinking to high-throughput screening for false-negative rate estimation

High‐Throughput Measurements of Biochemical Responses Using the Plate::Vision Multimode 96 Minilens Array Reader

A homogeneous fluorescence polarization assay adaptable for a range of protein serine/threonine and tyrosine kinases

Kinetic measurements of cell surface E-selectin/carbohydrate ligand interactions

N-substituted sultam carboxylic acids as novel glycogen synthase activators

Decomposition of Acid Dye by TiO2 Thin Films Prepared by the Sol−Gel Method

Primary Structure and Functional Activity of a Phosphatidylinositol-Glycan Specific Phospholipase D

High-throughput methods for measuring heparanase activity and screening potential antimetastatic and anti-inflammatory agents

Protein-protein interactions involved in the recognition of p27 by E3 ubiquitin ligase

[56] Glycosylphosphatidylinositol-specific phospholipase D

Abstract LB006: PC14586: The first orally bioavailable small molecule reactivator of Y220C mutant p53 in clinical development

Five distinct calcium and phospholipid binding proteins share homology with lipocortin I

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