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Therapeutic potentials of NOP and MOP receptor coactivation for the treatment of pain and opioid abuse

Journal of neuroscience research, 2022-01, Vol.100 (1), p.191-202

2022

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Translational value of non-human primates in opioid research

Experimental neurology, 2021-04, Vol.338, p.113602-113602, Article 113602

2021

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Effects of NOP-Related Ligands in Nonhuman Primates

Handbook of experimental pharmacology, 2019-01, Vol.254, p.323-343

2019

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Potential therapeutic targets for the treatment of opioid abuse and pain

Advances in pharmacology (1990), 2022, Vol.93, p.335

2022

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Distinct functions of opioid-related peptides and gastrin-releasing peptide in regulating itch and pain in the spinal cord of primates

Scientific reports, 2015-06, Vol.5 (1), p.11676-11676, Article 11676

2015

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A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates

Science translational medicine, 2018-08, Vol.10 (456)

2018

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Functional Profile of Systemic and Intrathecal Cebranopadol in Nonhuman Primates

Anesthesiology (Philadelphia), 2021-09, Vol.135 (3), p.482-493

2021

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Central N/OFQ-NOP Receptor System in Pain Modulation

Advances in pharmacology (1990), 2016-01, Vol.75, p.217

2016

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Functional consequences of short-term exposure to opioids versus cannabinoids in nonhuman primates

Neuropharmacology, 2023-02, Vol.223, p.109328-109328, Article 109328

2023

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Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch

Cell reports (Cambridge), 2020-04, Vol.31 (1), p.107472-107472, Article 107472

2020

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A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (37), p.E5511-E5518

2016

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GRP receptor and AMPA receptor cooperatively regulate itch-responsive neurons in the spinal dorsal horn

Neuropharmacology, 2020-06, Vol.170, p.108025-108025, Article 108025

2020

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BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates

British journal of anaesthesia : BJA, 2019-06, Vol.122 (6), p.e146-e156

2019

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Effects of stimulation of mu opioid and nociceptin/orphanin FQ peptide (NOP) receptors on alcohol drinking in rhesus monkeys

Neuropsychopharmacology (New York, N.Y.), 2019-07, Vol.44 (8), p.1476-1484

2019

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Physiological function of gastrin-releasing peptide and neuromedin B receptors in regulating itch scratching behavior in the spinal cord of mice

PloS one, 2013-06, Vol.8 (6), p.e67422-e67422

2013

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Synthesis of Enantiopure PZM21: A Biased Agonist of the Mu‐Opioid Receptor

European journal of organic chemistry, 2018-08, Vol.2018 (29), p.4006-4012

2018

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Effects of the NOP agonist SCH221510 on producing and attenuating reinforcing effects as measured by drug self-administration in rats

European journal of pharmacology, 2014-12, Vol.745, p.182-189

2014

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Functional roles of neuromedin B and gastrin-releasing peptide in regulating itch and pain in the spinal cord of non-human primates

Biochemical pharmacology, 2022-04, Vol.198, p.114972, Article 114972

2022

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The role of central gastrin-releasing peptide and neuromedin B receptors in the modulation of scratching behavior in rats

The Journal of pharmacology and experimental therapeutics, 2011-06, Vol.337 (3), p.822

2011

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Pharmacological studies on the NOP and opioid receptor agonist PWT2-[Dmt1]N/OFQ(1-13)

European journal of pharmacology, 2017-01, Vol.794, p.115-126

2017

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ノシセプチン受容体を標的とした安全なオピオイド鎮痛薬の可能性

日本薬理学雑誌, 2021, Vol.156(3), pp.139-144

2021

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The Therapeutic Potential of Nociceptin/Orphanin FQ Receptor Agonists as Analgesics without Abuse Liability

ACS chemical neuroscience, 2013-02, Vol.4 (2), p.214-224

2013

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Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain

Psychopharmacology, 2014-04, Vol.231 (7), p.1377-1387

2014

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Long-lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112

Pain (Amsterdam), 2010-01, Vol.148 (1), p.107

2010

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Altered expression of glial markers, chemokines, and opioid receptors in the spinal cord of type 2 diabetic monkeys

Biochimica et biophysica acta. Molecular basis of disease, 2017-01, Vol.1863 (1), p.274-283

2017

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Therapeutic potentials of NOP and MOP receptor coactivation for the treatment of pain and opioid abuse

Translational value of non-human primates in opioid research

Effects of NOP-Related Ligands in Nonhuman Primates

Potential therapeutic targets for the treatment of opioid abuse and pain

Distinct functions of opioid-related peptides and gastrin-releasing peptide in regulating itch and pain in the spinal cord of primates

A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates

Functional Profile of Systemic and Intrathecal Cebranopadol in Nonhuman Primates

Central N/OFQ-NOP Receptor System in Pain Modulation

Functional consequences of short-term exposure to opioids versus cannabinoids in nonhuman primates

Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch

A novel orvinol analog, BU08028, as a safe opioid analgesic without abuse liability in primates

GRP receptor and AMPA receptor cooperatively regulate itch-responsive neurons in the spinal dorsal horn

BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates

Effects of stimulation of mu opioid and nociceptin/orphanin FQ peptide (NOP) receptors on alcohol drinking in rhesus monkeys

Physiological function of gastrin-releasing peptide and neuromedin B receptors in regulating itch scratching behavior in the spinal cord of mice

Synthesis of Enantiopure PZM21: A Biased Agonist of the Mu‐Opioid Receptor

Effects of the NOP agonist SCH221510 on producing and attenuating reinforcing effects as measured by drug self-administration in rats

Functional roles of neuromedin B and gastrin-releasing peptide in regulating itch and pain in the spinal cord of non-human primates

The role of central gastrin-releasing peptide and neuromedin B receptors in the modulation of scratching behavior in rats

Pharmacological studies on the NOP and opioid receptor agonist PWT2-[Dmt1]N/OFQ(1-13)

ノシセプチン受容体を標的とした安全なオピオイド鎮痛薬の可能性

The Therapeutic Potential of Nociceptin/Orphanin FQ Receptor Agonists as Analgesics without Abuse Liability

Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain

Long-lasting antinociceptive spinal effects in primates of the novel nociceptin/orphanin FQ receptor agonist UFP-112

Altered expression of glial markers, chemokines, and opioid receptors in the spinal cord of type 2 diabetic monkeys

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