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Dual Inhibitors of Human DNA Topoisomerase II and Other Cancer-Related Targets

Journal of medicinal chemistry, 2020-02, Vol.63 (3), p.884-904

2020

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Benzothiazole-based Compounds in Antibacterial Drug Discovery

Current medicinal chemistry, 2018-01, Vol.25 (38), p.5218-5236

2018

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ATP-competitive DNA gyrase and topoisomerase IV inhibitors as antibacterial agents

Expert opinion on therapeutic patents, 2019-03, Vol.29 (3), p.171-180

2019

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Rational design of balanced dual-targeting antibiotics with limited resistance

PLoS biology, 2020-10, Vol.18 (10), p.e3000819

2020

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Antibacterial and Antibiofilm Potentials of Marine Pyrrole-2-Aminoimidazole Alkaloids and their Synthetic Analogs

Mini reviews in medicinal chemistry, 2018-01, Vol.18 (19), p.1640-1658

2018

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Cathepsin X promotes 6-hydroxydopamine-induced apoptosis of PC12 and SH-SY5Y cells

Neuropharmacology, 2014-07, Vol.82, p.121-131

2014

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Isoform selective voltage-gated sodium channel modulators and the therapy of pain

Current medicinal chemistry, 2014-01, Vol.21 (2), p.164-186

2014

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2-Aminoimidazoles in medicinal chemistry

Mini reviews in medicinal chemistry, 2013-11, Vol.13 (13), p.1921-1943

2013

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Recent advances in the synthesis of 2H-1,4-benzoxazin-3-(4H)-ones and 3,4-dihydro-2H-1,4-benzoxazines

Tetrahedron, 2005-08, Vol.61 (31), p.7325-7348

2005

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Synthesis and Evaluation of Spumigin Analogues Library with Thrombin Inhibitory Activity

Marine drugs, 2018-10, Vol.16 (11), p.413

2018

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The application of Freidinger lactams and their analogs in the design of conformationally constrained peptidomimetics

Current medicinal chemistry, 2006-06, Vol.13 (13), p.1525-1556

2006

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Characterization of Endogenous Sodium Channels in the ND7-23 Neuroblastoma Cell Line: Implications for Use as a Heterologous Ion Channel Expression System Suitable for Automated Patch Clamp Screening

Assay and drug development technologies, 2016-03, Vol.14 (2), p.109-130

2016

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Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation

Pharmaceutics, 2020-12, Vol.13 (1), p.6

2020

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Multitarget antithrombotic drugs

Current topics in medicinal chemistry, 2011-11, Vol.11 (22), p.2834-2848

2011

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Efficient Synthesis of Hydroxy-Substituted 2‑Aminobenzo[d]thiazole-6-carboxylic Acid Derivatives as New Building Blocks in Drug Discovery

ACS omega, 2020-04, Vol.5 (14), p.8305-8311

2020

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Recent Progress in Diaryl Ether Synthesis

Synthesis (Stuttgart), 2006-07, Vol.2006 (14), p.2271-2285

2006

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Novel 2-thioxothiazolidin-4-one inhibitors of bacterial MurD ligase targeting d-Glu- and diphosphate-binding sites

European journal of medicinal chemistry, 2011-09, Vol.46 (9), p.3964-3975

2011

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Practical Synthesis and Application of Halogen-Doped Pyrrole Building Blocks

ACS omega, 2021-04, Vol.6 (14), p.9723-9730

2021

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Novel Potent and Selective Thrombin Inhibitors Based on a Central 1,4-Benzoxazin-3(4H)-one Scaffold

Journal of medicinal chemistry, 2008-05, Vol.51 (9), p.2863-2867

2008

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Dual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus

ACS medicinal chemistry letters, 2012-08, Vol.3 (8), p.626-630

2012

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Efflux pump inhibitors of clinically relevant multidrug resistant bacteria

Medicinal research reviews, 2019-11, Vol.39 (6), p.2460-2504

2019

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Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (1), p.153-157

2009

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Synthesis of ethyl 3-(hydroxyphenoxy)benzyl butylphosphonates as potential antigen 85C inhibitors

Tetrahedron, 2007-10, Vol.63 (43), p.10698-10708

2007

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Action of clathrodin and analogues on voltage-gated sodium channels

Marine drugs, 2014-04, Vol.12 (4), p.2132-2143

2014

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Fluconazole-malonic acid (1/1)

Acta crystallographica. Section E, Structure reports online, 2013-03, Vol.69 (Pt 3), p.o378-o379

2013

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Dual Inhibitors of Human DNA Topoisomerase II and Other Cancer-Related Targets

Benzothiazole-based Compounds in Antibacterial Drug Discovery

ATP-competitive DNA gyrase and topoisomerase IV inhibitors as antibacterial agents

Rational design of balanced dual-targeting antibiotics with limited resistance

Antibacterial and Antibiofilm Potentials of Marine Pyrrole-2-Aminoimidazole Alkaloids and their Synthetic Analogs

Cathepsin X promotes 6-hydroxydopamine-induced apoptosis of PC12 and SH-SY5Y cells

Isoform selective voltage-gated sodium channel modulators and the therapy of pain

2-Aminoimidazoles in medicinal chemistry

Recent advances in the synthesis of 2H-1,4-benzoxazin-3-(4H)-ones and 3,4-dihydro-2H-1,4-benzoxazines

Synthesis and Evaluation of Spumigin Analogues Library with Thrombin Inhibitory Activity

The application of Freidinger lactams and their analogs in the design of conformationally constrained peptidomimetics

Characterization of Endogenous Sodium Channels in the ND7-23 Neuroblastoma Cell Line: Implications for Use as a Heterologous Ion Channel Expression System Suitable for Automated Patch Clamp Screening

Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation

Multitarget antithrombotic drugs

Efficient Synthesis of Hydroxy-Substituted 2‑Aminobenzo[d]thiazole-6-carboxylic Acid Derivatives as New Building Blocks in Drug Discovery

Recent Progress in Diaryl Ether Synthesis

Novel 2-thioxothiazolidin-4-one inhibitors of bacterial MurD ligase targeting d-Glu- and diphosphate-binding sites

Practical Synthesis and Application of Halogen-Doped Pyrrole Building Blocks

Novel Potent and Selective Thrombin Inhibitors Based on a Central 1,4-Benzoxazin-3(4H)-one Scaffold

Dual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus

Efflux pump inhibitors of clinically relevant multidrug resistant bacteria

Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase

Synthesis of ethyl 3-(hydroxyphenoxy)benzyl butylphosphonates as potential antigen 85C inhibitors

Action of clathrodin and analogues on voltage-gated sodium channels

Fluconazole-malonic acid (1/1)

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