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HOW CELLS RESPOND TO INTERFERONS

Annual review of biochemistry, 1998-01, Vol.67 (1), p.227-264

1998

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Mutational Switch of an IL-6 Response to an Interferon-γ-like Response

Proceedings of the National Academy of Sciences - PNAS, 2002-06, Vol.99 (12), p.8043-8047

2002

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Of JAKs, STATs, blind watchmakers, jeeps and trains

FEBS Letters, 2003-07, Vol.546 (1), p.1-5

2003

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Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

Science (American Association for the Advancement of Science), 1994-06, Vol.264 (5164), p.1415-1421

1994

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P-STAT1 mediates higher-order chromatin remodelling of the human MHC in response to IFNγ

Journal of cell science, 2007-09, Vol.120 (18), p.3262-3270

2007

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Jaks and Stats in signaling by the cytokine receptor superfamily

Trends in Genetics, 1995-02, Vol.11 (2), p.69-74

1995

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The Antiviral Response to Gamma Interferon

Journal of Virology, 2002-09, Vol.76 (18), p.9060-9068

2002

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Differential responses to IFN-alpha subtypes in human T cells and dendritic cells

The Journal of immunology (1950), 2003-11, Vol.171 (10), p.5255-5263

2003

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A Single Phosphotyrosine Residue of Stat91 Required for Gene Activation by Interferon-γ

Science (American Association for the Advancement of Science), 1993-09, Vol.261 (5129), p.1744-1746

1993

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Contribution of STAT SH2 Groups to Specific Interferon Signaling by the Jak-STAT Pathway

Science (American Association for the Advancement of Science), 1995-03, Vol.267 (5202), p.1347-1349

1995

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Cell-type and donor-specific transcriptional responses to interferon-alpha. Use of customized gene arrays

The Journal of biological chemistry, 2002-12, Vol.277 (51), p.49428

2002

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Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression

Biochemical journal, 1998-11, Vol.335 ( Pt 3) (3), p.557-565

1998

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STAT1 from the cell membrane to the DNA

The EMBO journal, 2001-05, Vol.20 (10), p.2508-2517

2001

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Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex

Molecular and Cellular Biology, 1996-12, Vol.16 (12), p.6957-6964

1996

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Role of STAT2 in the alpha interferon signaling pathway

Molecular and Cellular Biology, 1995-03, Vol.15 (3), p.1312-1317

1995

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Growth Hormone and Prolactin Stimulate Tyrosine Phosphorylation of Insulin Receptor Substrate-1, -2, and -3, Their Association with p85 Phosphatidylinositol 3-Kinase (PI3-kinase), and Concomitantly PI3-kinase Activation via JAK2 Kinase

The Journal of biological chemistry, 1998-06, Vol.273 (25), p.15719-15726

1998

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Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor

Molecular and Cellular Biology, 1996-01, Vol.16 (1), p.369-375

1996

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A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses

Molecular and Cellular Biology, 1997-02, Vol.17 (2), p.695-706

1997

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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

Cell, 1990-07, Vol.62 (2), p.379-390

1990

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Jak1 plays an essential role for receptor phosphorylation and stat activation in response to granulocyte colony-stimulating factor

Blood, 1997-07, Vol.90 (2), p.597-604

1997

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Function of Stat2 protein in transcriptional activation by alpha interferon

Molecular and Cellular Biology, 1996-01, Vol.16 (1), p.288-293

1996

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Mapping of a Region within the N Terminus of Jak1 Involved in Cytokine Receptor Interaction

The Journal of biological chemistry, 2001-10, Vol.276 (40), p.37451-37458

2001

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Janus Kinase-dependent Activation of Insulin Receptor Substrate 1 in Response to Interleukin-4, Oncostatin M, and the Interferons

The Journal of biological chemistry, 1997-09, Vol.272 (39), p.24183-24190

1997

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Activation of the Janus Kinase/Signal Transducer and Activator of Transcription Pathway by Osmotic Shock

The Journal of biological chemistry, 1998-09, Vol.273 (36), p.22962-22968

1998

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High-Frequency Mutagenesis of Human Cells and Characterization of a Mutant Unresponsive to both α and γ Interferons

Proceedings of the National Academy of Sciences - PNAS, 1991-12, Vol.88 (24), p.11455-11459

1991

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HOW CELLS RESPOND TO INTERFERONS

Mutational Switch of an IL-6 Response to an Interferon-γ-like Response

Of JAKs, STATs, blind watchmakers, jeeps and trains

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

P-STAT1 mediates higher-order chromatin remodelling of the human MHC in response to IFNγ

Jaks and Stats in signaling by the cytokine receptor superfamily

The Antiviral Response to Gamma Interferon

Differential responses to IFN-alpha subtypes in human T cells and dendritic cells

A Single Phosphotyrosine Residue of Stat91 Required for Gene Activation by Interferon-γ

Contribution of STAT SH2 Groups to Specific Interferon Signaling by the Jak-STAT Pathway

Cell-type and donor-specific transcriptional responses to interferon-alpha. Use of customized gene arrays

Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression

STAT1 from the cell membrane to the DNA

Interactions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complex

Role of STAT2 in the alpha interferon signaling pathway

Growth Hormone and Prolactin Stimulate Tyrosine Phosphorylation of Insulin Receptor Substrate-1, -2, and -3, Their Association with p85 Phosphatidylinositol 3-Kinase (PI3-kinase), and Concomitantly PI3-kinase Activation via JAK2 Kinase

Roles of JAKs in activation of STATs and stimulation of c-fos gene expression by epidermal growth factor

A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

Jak1 plays an essential role for receptor phosphorylation and stat activation in response to granulocyte colony-stimulating factor

Function of Stat2 protein in transcriptional activation by alpha interferon

Mapping of a Region within the N Terminus of Jak1 Involved in Cytokine Receptor Interaction

Janus Kinase-dependent Activation of Insulin Receptor Substrate 1 in Response to Interleukin-4, Oncostatin M, and the Interferons

Activation of the Janus Kinase/Signal Transducer and Activator of Transcription Pathway by Osmotic Shock

High-Frequency Mutagenesis of Human Cells and Characterization of a Mutant Unresponsive to both α and γ Interferons

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