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Crystal structure of the motor domain of centromere‐associated protein E in complex with a non‐hydrolysable ATP analogue

FEBS letters, 2023-04, Vol.597 (8), p.1138-1148

2023

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Various effects of two types of kinesin-5 inhibitors on mitosis and cell proliferation

Biochemical pharmacology, 2021-11, Vol.193, p.114789-114789, Article 114789

2021

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Selective Inhibition of Spindle Microtubules by a Tubulin-Binding Quinazoline Derivative

Molecular pharmacology, 2019-11, Vol.96 (5), p.609-618

2019

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Structural Basis of New Allosteric Inhibition in Kinesin Spindle Protein Eg5

ACS chemical biology, 2015-04, Vol.10 (4), p.1128-1136

2015

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The Ubiquitin Ligase Activity in the DDB2 and CSA Complexes Is Differentially Regulated by the COP9 Signalosome in Response to DNA Damage

Cell, 2003-05, Vol.113 (3), p.357-367

2003

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Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A16 and 28

Pharmacogenetics and genomics, 2007-07, Vol.17 (7), p.497-504

2007

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Structure–Activity Relationships of Carboline and Carbazole Derivatives as a Novel Class of ATP-Competitive Kinesin Spindle Protein Inhibitors

Journal of medicinal chemistry, 2011-07, Vol.54 (13), p.4839-4846

2011

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Coordinated histone modifications mediated by a CtBP co-repressor complex

Nature (London), 2003-04, Vol.422 (6933), p.735-738

2003

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Pharmacokinetics of Gemcitabine in Japanese Cancer Patients: The Impact of a Cytidine Deaminase Polymorphism

Journal of clinical oncology, 2007-01, Vol.25 (1), p.32-42

2007

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Functional analysis of SNPs variants of BCRP/ABCG2

Pharmaceutical research, 2004-10, Vol.21 (10), p.1895-1903

2004

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Silk Gland Factor-2, Involved in Fibroin Gene Transcription, Consists of LIM Homeodomain, LIM-interacting, and Single-stranded DNA-binding Proteins

The Journal of biological chemistry, 2013-11, Vol.288 (44), p.31581-31591

2013

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Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region

Drug metabolism and disposition, 2004-01, Vol.32 (1), p.149

2004

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Comparative Study of in Vitro Digestibility of Food Proteins and Effect of Preheating on the Digestion

Biological and Pharmaceutical Bulletin, 2003, Vol.26(7), pp.969-973

2003

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UGT1A1 Haplotypes Associated with Reduced Glucuronidation and Increased Serum Bilirubin in Irinotecan‐administered Japanese Patients with Cancer

Clinical pharmacology and therapeutics, 2004-06, Vol.75 (6), p.501-515

2004

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Distal Promoter Regions Are Responsible for Differential Regulation of Human Orosomucoid-1 and -2 Gene Expression and Acute Phase Responses

Biological and Pharmaceutical Bulletin, 2014/01/01, Vol.37(1), pp.164-168

2014

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Investigating toxicity specific to adjuvanted vaccines

Regulatory toxicology and pharmacology, 2017-12, Vol.91, p.29-38

2017

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Binding of PDZ-RhoGEF to ATP-binding Cassette Transporter A1 (ABCA1) Induces Cholesterol Efflux through RhoA Activation and Prevention of Transporter Degradation

The Journal of biological chemistry, 2010-05, Vol.285 (21), p.16369-16377

2010

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Identification of benzo[d]pyrrolo[2,1-b]thiazole derivatives as CENP-E inhibitors

Biochemical and biophysical research communications, 2019-11, Vol.519 (3), p.505-511

2019

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Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C> T (P229L) found in an African-American

Drug metabolism and disposition, 2005-03, Vol.33 (3), p.458

2005

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Substrate-dependent functional alterations of seven CYP2C9 variants found in Japanese subjects

Drug metabolism and disposition, 2009-09, Vol.37 (9), p.1895

2009

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Association of carboxylesterase 1A genotypes with irinotecan pharmacokinetics in Japanese cancer patients

British journal of clinical pharmacology, 2010-08, Vol.70 (2), p.222-233

2010

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Design, synthesis, and evaluation of a novel prodrug, a S-trityl-l-cysteine derivative targeting kinesin spindle protein

European journal of medicinal chemistry, 2021-04, Vol.215, p.113288-113288, Article 113288

2021

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Cytoprotection against oxidative stress-induced damage of astrocytes by extracellular ATP via P2Y1 receptors

Glia, 2005-01, Vol.49 (2), p.288-300

2005

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Construction of possible integrated predictive index based on EGFR and ANXA3 polymorphisms for chemotherapy response in fluoropyrimidine-treated Japanese gastric cancer patients using a bioinformatic method

BMC cancer, 2015-10, Vol.15 (1), p.718-718, Article 718

2015

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