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Crystal structure of the motor domain of centromere‐associated protein E in complex with a non‐hydrolysable ATP analogue

FEBS letters, 2023-04, Vol.597 (8), p.1138-1148

2023

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Various effects of two types of kinesin-5 inhibitors on mitosis and cell proliferation

Biochemical pharmacology, 2021-11, Vol.193, p.114789-114789, Article 114789

2021

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Selective Inhibition of Spindle Microtubules by a Tubulin-Binding Quinazoline Derivative

Molecular pharmacology, 2019-11, Vol.96 (5), p.609-618

2019

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The Ubiquitin Ligase Activity in the DDB2 and CSA Complexes Is Differentially Regulated by the COP9 Signalosome in Response to DNA Damage

Cell, 2003-05, Vol.113 (3), p.357-367

2003

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Structural Basis of New Allosteric Inhibition in Kinesin Spindle Protein Eg5

ACS chemical biology, 2015-04, Vol.10 (4), p.1128-1136

2015

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Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A16 and 28

Pharmacogenetics and genomics, 2007-07, Vol.17 (7), p.497-504

2007

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Structure–Activity Relationships of Carboline and Carbazole Derivatives as a Novel Class of ATP-Competitive Kinesin Spindle Protein Inhibitors

Journal of medicinal chemistry, 2011-07, Vol.54 (13), p.4839-4846

2011

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Coordinated histone modifications mediated by a CtBP co-repressor complex

Nature (London), 2003-04, Vol.422 (6933), p.735-738

2003

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Pharmacokinetics of Gemcitabine in Japanese Cancer Patients: The Impact of a Cytidine Deaminase Polymorphism

Journal of clinical oncology, 2007-01, Vol.25 (1), p.32-42

2007

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Silk Gland Factor-2, Involved in Fibroin Gene Transcription, Consists of LIM Homeodomain, LIM-interacting, and Single-stranded DNA-binding Proteins

The Journal of biological chemistry, 2013-11, Vol.288 (44), p.31581-31591

2013

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Functional analysis of SNPs variants of BCRP/ABCG2

Pharmaceutical research, 2004-10, Vol.21 (10), p.1895-1903

2004

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Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region

Drug metabolism and disposition, 2004-01, Vol.32 (1), p.149-154

2004

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Comparative Study of in Vitro Digestibility of Food Proteins and Effect of Preheating on the Digestion

Biological and Pharmaceutical Bulletin, 2003, Vol.26(7), pp.969-973

2003

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UGT1A1 Haplotypes Associated with Reduced Glucuronidation and Increased Serum Bilirubin in Irinotecan‐administered Japanese Patients with Cancer

Clinical pharmacology and therapeutics, 2004-06, Vol.75 (6), p.501-515

2004

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Distal Promoter Regions Are Responsible for Differential Regulation of Human Orosomucoid-1 and -2 Gene Expression and Acute Phase Responses

Biological and Pharmaceutical Bulletin, 2014/01/01, Vol.37(1), pp.164-168

2014

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Investigating toxicity specific to adjuvanted vaccines

Regulatory toxicology and pharmacology, 2017-12, Vol.91, p.29-38

2017

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Binding of PDZ-RhoGEF to ATP-binding Cassette Transporter A1 (ABCA1) Induces Cholesterol Efflux through RhoA Activation and Prevention of Transporter Degradation

The Journal of biological chemistry, 2010-05, Vol.285 (21), p.16369-16377

2010

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Identification of benzo[d]pyrrolo[2,1-b]thiazole derivatives as CENP-E inhibitors

Biochemical and biophysical research communications, 2019-11, Vol.519 (3), p.505-511

2019

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Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C> T (P229L) found in an African-American

Drug metabolism and disposition, 2005-03, Vol.33 (3), p.458-465

2005

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Association of carboxylesterase 1A genotypes with irinotecan pharmacokinetics in Japanese cancer patients

British journal of clinical pharmacology, 2010-08, Vol.70 (2), p.222-233

2010

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Substrate-dependent functional alterations of seven CYP2C9 variants found in Japanese subjects

Drug metabolism and disposition, 2009-09, Vol.37 (9), p.1895-1903

2009

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Design, synthesis, and evaluation of a novel prodrug, a S-trityl-l-cysteine derivative targeting kinesin spindle protein

European journal of medicinal chemistry, 2021-04, Vol.215, p.113288-113288, Article 113288

2021

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Construction of possible integrated predictive index based on EGFR and ANXA3 polymorphisms for chemotherapy response in fluoropyrimidine-treated Japanese gastric cancer patients using a bioinformatic method

BMC cancer, 2015-10, Vol.15 (1), p.718-718, Article 718

2015

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Cytoprotection against oxidative stress-induced damage of astrocytes by extracellular ATP via P2Y1 receptors

Glia, 2005-01, Vol.49 (2), p.288-300

2005

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Crystal structure of the motor domain of centromere‐associated protein E in complex with a non‐hydrolysable ATP analogue

Various effects of two types of kinesin-5 inhibitors on mitosis and cell proliferation

Selective Inhibition of Spindle Microtubules by a Tubulin-Binding Quinazoline Derivative

The Ubiquitin Ligase Activity in the DDB2 and CSA Complexes Is Differentially Regulated by the COP9 Signalosome in Response to DNA Damage

Structural Basis of New Allosteric Inhibition in Kinesin Spindle Protein Eg5

Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A16 and 28

Structure–Activity Relationships of Carboline and Carbazole Derivatives as a Novel Class of ATP-Competitive Kinesin Spindle Protein Inhibitors

Coordinated histone modifications mediated by a CtBP co-repressor complex

Pharmacokinetics of Gemcitabine in Japanese Cancer Patients: The Impact of a Cytidine Deaminase Polymorphism

Silk Gland Factor-2, Involved in Fibroin Gene Transcription, Consists of LIM Homeodomain, LIM-interacting, and Single-stranded DNA-binding Proteins

Functional analysis of SNPs variants of BCRP/ABCG2

Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region

Comparative Study of in Vitro Digestibility of Food Proteins and Effect of Preheating on the Digestion

UGT1A1 Haplotypes Associated with Reduced Glucuronidation and Increased Serum Bilirubin in Irinotecan‐administered Japanese Patients with Cancer

Distal Promoter Regions Are Responsible for Differential Regulation of Human Orosomucoid-1 and -2 Gene Expression and Acute Phase Responses

Investigating toxicity specific to adjuvanted vaccines

Binding of PDZ-RhoGEF to ATP-binding Cassette Transporter A1 (ABCA1) Induces Cholesterol Efflux through RhoA Activation and Prevention of Transporter Degradation

Identification of benzo[d]pyrrolo[2,1-b]thiazole derivatives as CENP-E inhibitors

Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C> T (P229L) found in an African-American

Association of carboxylesterase 1A genotypes with irinotecan pharmacokinetics in Japanese cancer patients

Substrate-dependent functional alterations of seven CYP2C9 variants found in Japanese subjects

Design, synthesis, and evaluation of a novel prodrug, a S-trityl-l-cysteine derivative targeting kinesin spindle protein

Haplotypes of CYP3A4 and their close linkage with CYP3A5 haplotypes in a Japanese population

Construction of possible integrated predictive index based on EGFR and ANXA3 polymorphisms for chemotherapy response in fluoropyrimidine-treated Japanese gastric cancer patients using a bioinformatic method

Cytoprotection against oxidative stress-induced damage of astrocytes by extracellular ATP via P2Y1 receptors

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