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Chronic unpredictable mild stress induced depression-like behaviours and glutamate-glutamine cycling dysfunctions in both blood and brain of mice

Pharmaceutical biology, 2019-01, Vol.57 (1), p.280-286

2019

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Acute EPA-induced learning and memory impairment in mice is prevented by DHA

Nature communications, 2020-10, Vol.11 (1), p.5465-5465, Article 5465

2020

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Block Copolymer Colloidal Particles with Unique Structures through Three-dimensional Confined Assembly and Disassembly

Chinese journal of polymer science, 2019-08, Vol.37 (8), p.744-759

2019

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Anti-oxidant polydatin (piceid) protects against substantia nigral motor degeneration in multiple rodent models of Parkinson's disease

Molecular neurodegeneration, 2015-03, Vol.10 (1), p.4-4, Article 4

2015

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Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in Parkinson’s disease models

Acta pharmacologica Sinica, 2021-12, Vol.42 (12), p.1991-2003

2021

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Low lattice thermal conductivity and enhanced thermoelectric performance of SnTe via chemical electroless plating of Ag

Rare metals, 2022, Vol.41 (1), p.86-95

2022

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Anxiolytic-like effects of YL-IPA08, a potent ligand for the translocator protein (18 kDa) in animal models of post-traumatic stress disorder

The international journal of neuropsychopharmacology, 2014-10, Vol.17 (10), p.1659-1669

2014

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A new polyhydroxylated oleanane triterpenoid from the roots of Rhodomyrtus tomentosa

Natural product research, 2020-01, Vol.34 (2), p.204-209

2020

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Discovery of 2‐(3,4‐dialkoxyphenyl)‐2‐(substituted pyridazin‐3‐yl)acetonitriles as phosphodiesterase 4 inhibitors with anti‐neuroinflammation potential based on three‐dimensional quantitative structure–activity relationship study

Chemical biology & drug design, 2019-04, Vol.93 (4), p.484-502

2019

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Sulforaphane attenuates di‐N‐butylphthalate‐induced reproductive damage in pubertal mice: Involvement of the Nrf2‐antioxidant system

Environmental toxicology, 2017-07, Vol.32 (7), p.1908-1917

2017

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Reciprocal Substitution Between Methamphetamine and Heroin in Terms of Reinforcement Effects in Rats

Frontiers in psychiatry, 2020-07, Vol.11, p.750-750

2020

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Antidepressant-like effects of 071031B, a novel serotonin and norepinephrine reuptake inhibitor

European neuropsychopharmacology, 2013-07, Vol.23 (7), p.728-741

2013

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Protective effect of gui zhi (Ramulus Cinnamomi) on abnormal levels of four amino acid neurotransmitters by chronically ma huang (Herb Ephedra) intoxicated prefrontal cortex in rats treated with a ma huang-gui zhi herb pair

Journal of ethnopharmacology, 2020-03, Vol.249, p.112408, Article 112408

2020

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Memory deficits and neurochemical changes induced by C-reactive protein in rats: implication in Alzheimer’s disease

Psychopharmacologia, 2009-07, Vol.204 (4), p.705-714

2009

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Advances in the development of phosphodiesterase 7 inhibitors

European journal of medicinal chemistry, 2023-03, Vol.250, p.115194-115194, Article 115194

2023

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Discovery of novel 2,3-dihydro-1H-inden-1-ones as dual PDE4/AChE inhibitors with more potency against neuroinflammation for the treatment of Alzheimer's disease

European journal of medicinal chemistry, 2022-08, Vol.238, p.114503-114503, Article 114503

2022

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Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats

Acta pharmacologica Sinica, 2023-03, Vol.44 (3), p.499-512

2023

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Antipyretic Effects of Eupatorium chinense and Its Mechanism

Chinese herbal medicines, 2015-11, Vol.7 (4), p.323-327

2015

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Discovery of arylbenzylamines as PDE4 inhibitors with potential neuroprotective effect

European journal of medicinal chemistry, 2019-04, Vol.168, p.221-231

2019

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Discovery of novel trimethoxyphenylbenzo[d]oxazoles as dual tubulin/PDE4 inhibitors capable of inducing apoptosis at G2/M phase arrest in glioma and lung cancer cells

European journal of medicinal chemistry, 2021-11, Vol.224, p.113700-113700, Article 113700

2021

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The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats

The international journal of neuropsychopharmacology, 2012-07, Vol.15 (6), p.749-766

2012

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Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents

Psychopharmacology, 2017-10, Vol.234 (20), p.3143-3151

2017

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Intersubunit Concerted Cooperative and cis-Type Mechanisms Modulate Allosteric Gating in Two-Pore-Domain Potassium Channel TREK-2

Frontiers in cellular neuroscience, 2016-05, Vol.10, p.127-127

2016

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Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF- κ B Inhibition

The Journal of pharmacology and experimental therapeutics, 2017-07, Vol.362 (1), p.67-77

2017

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Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25–35 or Aβ1–40 peptide in rats

Psychopharmacologia, 2010-10, Vol.212 (2), p.181-191

2010

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Chronic unpredictable mild stress induced depression-like behaviours and glutamate-glutamine cycling dysfunctions in both blood and brain of mice

Acute EPA-induced learning and memory impairment in mice is prevented by DHA

Block Copolymer Colloidal Particles with Unique Structures through Three-dimensional Confined Assembly and Disassembly

Anti-oxidant polydatin (piceid) protects against substantia nigral motor degeneration in multiple rodent models of Parkinson's disease

Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in Parkinson’s disease models

Low lattice thermal conductivity and enhanced thermoelectric performance of SnTe via chemical electroless plating of Ag

Anxiolytic-like effects of YL-IPA08, a potent ligand for the translocator protein (18 kDa) in animal models of post-traumatic stress disorder

A new polyhydroxylated oleanane triterpenoid from the roots of Rhodomyrtus tomentosa

Discovery of 2‐(3,4‐dialkoxyphenyl)‐2‐(substituted pyridazin‐3‐yl)acetonitriles as phosphodiesterase 4 inhibitors with anti‐neuroinflammation potential based on three‐dimensional quantitative structure–activity relationship study

Sulforaphane attenuates di‐N‐butylphthalate‐induced reproductive damage in pubertal mice: Involvement of the Nrf2‐antioxidant system

Reciprocal Substitution Between Methamphetamine and Heroin in Terms of Reinforcement Effects in Rats

Antidepressant-like effects of 071031B, a novel serotonin and norepinephrine reuptake inhibitor

Protective effect of gui zhi (Ramulus Cinnamomi) on abnormal levels of four amino acid neurotransmitters by chronically ma huang (Herb Ephedra) intoxicated prefrontal cortex in rats treated with a ma huang-gui zhi herb pair

Memory deficits and neurochemical changes induced by C-reactive protein in rats: implication in Alzheimer’s disease

Advances in the development of phosphodiesterase 7 inhibitors

Discovery of novel 2,3-dihydro-1H-inden-1-ones as dual PDE4/AChE inhibitors with more potency against neuroinflammation for the treatment of Alzheimer's disease

Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats

Antipyretic Effects of Eupatorium chinense and Its Mechanism

Discovery of arylbenzylamines as PDE4 inhibitors with potential neuroprotective effect

Discovery of novel trimethoxyphenylbenzo[d]oxazoles as dual tubulin/PDE4 inhibitors capable of inducing apoptosis at G2/M phase arrest in glioma and lung cancer cells

The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats

Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents

Intersubunit Concerted Cooperative and cis-Type Mechanisms Modulate Allosteric Gating in Two-Pore-Domain Potassium Channel TREK-2

Novel Phosphodiesterase 4 Inhibitor FCPR03 Alleviates Lipopolysaccharide-Induced Neuroinflammation by Regulation of the cAMP/PKA/CREB Signaling Pathway and NF- κ B Inhibition

Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25–35 or Aβ1–40 peptide in rats

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