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Olipudase alfa for treatment of acid sphingomyelinase deficiency (ASMD): safety and efficacy in adults treated for 30 months

Journal of inherited metabolic disease, 2018-09, Vol.41 (5), p.829-838

2018

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Long-term efficacy of olipudase alfa in adults with acid sphingomyelinase deficiency (ASMD): Further clearance of hepatic sphingomyelin is associated with additional improvements in pro- and anti-atherogenic lipid profiles after 42 months of treatment

Molecular genetics and metabolism, 2020-09, Vol.131 (1-2), p.245-252

2020

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Plasma glucosylsphingosine correlations with baseline disease burden and response to eliglustat in two clinical trials of previously untreated adults with Gaucher disease type 1

Molecular genetics and metabolism, 2023-03, Vol.138 (3), p.107527-107527, Article 107527

2023

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Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Oral Venglustat in Healthy Volunteers

Clinical pharmacology in drug development, 2021-01, Vol.10 (1), p.86-98

2021

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Ultrasensitive and Automated 1 Pg/Ml Fluticasone Propionate Assay in Human Plasma Using LC–MS/MS

Bioanalysis, 2013-02, Vol.5 (4), p.423-435

2013

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Reassessment of tigecycline bone concentrations in volunteers undergoing elective orthopedic procedures

Journal of clinical pharmacology, 2014-01, Vol.54 (1), p.70-74

2014

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Sample Preparation for LC‐MS Bioanalysis of Urine, Cerebrospinal Fluid, Synovial Fluid, Sweat, Tears, and Aqueous Humor Samples

Sample Preparation in LC‐MS Bioanalysis, 2019, p.225-237

2019

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A sensitive human bone assay for quantitation of tigecycline using LC/MS/MS

Journal of pharmaceutical and biomedical analysis, 2008-11, Vol.48 (3), p.866-875

2008

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A novel antibiotic bone assay by liquid chromatography/tandem mass spectrometry for quantitation of tigecycline in rat bone

Journal of pharmaceutical and biomedical analysis, 2007-08, Vol.44 (4), p.970-979

2007

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Long-term efficacy of olipudase alfa in adults with acid sphingomyelinase deficiency (ASMD): Further clearance of hepatic sphingomyelin is associated with additional improvements in pro- and anti-atherogenic lipid profiles after 3.5 years of treatment

Molecular genetics and metabolism, 2019-02, Vol.126 (2), p.S142-S143

2019

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Safety, tolerability and pharmacokinetics of oral venglustat in Parkinson disease patients with a GBA mutation

Molecular genetics and metabolism, 2019-02, Vol.126 (2), p.S117-S117

2019

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A New Gas ChromatographyMass Spectrometry Method for Simultaneous Determination of Total and Free trans-3'-Hydroxycotinine and Cotinine in the Urine of Subjects Receiving Transdermal Nicotine

Clinical chemistry (Baltimore, Md.), 1999-01, Vol.45 (1), p.85-91

1999

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LC‐MS Bioanalysis of Drugs in Urine

Handbook of LC‐MS Bioanalysis, 2013, p.307-316

2013

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Determination of total serum sulfite by HPLC with fluorescence detection

Clinical chemistry (Baltimore, Md.), 1995-06, Vol.41 (6 Pt 1), p.897-903

1995

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Separation of urinary estrogens by micellar electrokinetic chromatography

Journal of chromatography. B, Biomedical applications, 1995-07, Vol.669 (1), p.15-26

1995

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Ultrasensitive and automated 1 pg/ml fluticasone propionate assay in human plasma using LC-MS/MS

Bioanalysis, 2013-02, Vol.5 (4), p.423

2013

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2020 White Paper on Recent Issues in Bioanalysis: BMV of Hybrid Assays, Acoustic MS, HRMS, Data Integrity, Endogenous Compounds, Microsampling and Microbiome

Bioanalysis, 2021-02, Vol.13 (4), p.203-238

2021

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2021 White Paper on Recent Issues in Bioanalysis: Mass Spec of Proteins, Extracellular Vesicles, CRISPR, Chiral Assays, Oligos; Nanomedicines Bioanalysis; ICH M10 Section 7.1; Non-Liquid & Rare Matrices; Regulatory Inputs

Bioanalysis, 2022-05, Vol.14 (9), p.505-580

2022

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2023 White Paper on Recent Issues in Bioanalysis: Deuterated Drugs; LNP; Tumor/FFPE Biopsy; Targeted Proteomics; Small Molecule Covalent Inhibitors; Chiral Bioanalysis; Remote Regulatory Assessments; Sample Reconciliation/Chain of Custody (PART 1A - Recommendations on Mass Spectrometry, Chromatography, Sample Preparation Latest Developments, Challenges, and Solutions and BMV/Regulated Bioanalysis PART 1B - Regulatory Agencies' Inputs on Regulated Bioanalysis/BMV, Biomarkers/IVD/CDx/BAV, Immunoge

Bioanalysis, 2024-05, Vol.16 (9), p.307-364

2024

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Evaluation of PAI-039 [{1-benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic acid], a novel plasminogen activator inhibitor-1 inhibitor, in a canine model of coronary artery thrombosis

The Journal of pharmacology and experimental therapeutics, 2005-08, Vol.314 (2), p.710

2005

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Olipudase alfa for treatment of acid sphingomyelinase deficiency (ASMD): safety and efficacy in adults treated for 30 months

Long-term efficacy of olipudase alfa in adults with acid sphingomyelinase deficiency (ASMD): Further clearance of hepatic sphingomyelin is associated with additional improvements in pro- and anti-atherogenic lipid profiles after 42 months of treatment

Plasma glucosylsphingosine correlations with baseline disease burden and response to eliglustat in two clinical trials of previously untreated adults with Gaucher disease type 1

Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Oral Venglustat in Healthy Volunteers

Ultrasensitive and Automated 1 Pg/Ml Fluticasone Propionate Assay in Human Plasma Using LC–MS/MS

Reassessment of tigecycline bone concentrations in volunteers undergoing elective orthopedic procedures

Sample Preparation for LC‐MS Bioanalysis of Urine, Cerebrospinal Fluid, Synovial Fluid, Sweat, Tears, and Aqueous Humor Samples

A sensitive human bone assay for quantitation of tigecycline using LC/MS/MS

A novel antibiotic bone assay by liquid chromatography/tandem mass spectrometry for quantitation of tigecycline in rat bone

Long-term efficacy of olipudase alfa in adults with acid sphingomyelinase deficiency (ASMD): Further clearance of hepatic sphingomyelin is associated with additional improvements in pro- and anti-atherogenic lipid profiles after 3.5 years of treatment

Safety, tolerability and pharmacokinetics of oral venglustat in Parkinson disease patients with a GBA mutation

A New Gas ChromatographyMass Spectrometry Method for Simultaneous Determination of Total and Free trans-3'-Hydroxycotinine and Cotinine in the Urine of Subjects Receiving Transdermal Nicotine

LC‐MS Bioanalysis of Drugs in Urine

Determination of total serum sulfite by HPLC with fluorescence detection

Separation of urinary estrogens by micellar electrokinetic chromatography

Ultrasensitive and automated 1 pg/ml fluticasone propionate assay in human plasma using LC-MS/MS

2020 White Paper on Recent Issues in Bioanalysis: BMV of Hybrid Assays, Acoustic MS, HRMS, Data Integrity, Endogenous Compounds, Microsampling and Microbiome

Safety, Pharmacokinetics, and Pharmacodynamics of Oral Venglustat in the Japanese and the Rest of the World Parkinson’s Disease Population With a GBA Mutation: Results from Part 1 of the MOVES-PD Study (809)

2021 White Paper on Recent Issues in Bioanalysis: Mass Spec of Proteins, Extracellular Vesicles, CRISPR, Chiral Assays, Oligos; Nanomedicines Bioanalysis; ICH M10 Section 7.1; Non-Liquid & Rare Matrices; Regulatory Inputs

Evaluation of PAI-039 [{1-benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic acid], a novel plasminogen activator inhibitor-1 inhibitor, in a canine model of coronary artery thrombosis

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