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N-Heterocyclic Carbene Capture by Cytochrome P450 3A4

Molecular pharmacology, 2016-07, Vol.90 (1), p.42-51

2016

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Evidence for an elevated aspartate pK(a) in the active site of human aromatase

The Journal of biological chemistry, 2015-01, Vol.290 (2), p.1186-1196

2015

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Noncovalent interactions dominate dynamic heme distortion in cytochrome P450 4B1

The Journal of biological chemistry, 2018-07, Vol.293 (29), p.11433-11446

2018

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Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1330-1347

2019

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Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents

European journal of medicinal chemistry, 2018-08, Vol.156, p.53-60

2018

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Rapid Chagas Disease Drug Target Discovery Using Directed Evolution in Drug-Sensitive Yeast

ACS chemical biology, 2017-02, Vol.12 (2), p.422-434

2017

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Biophysical characterization of Aptenodytes forsteri cytochrome P450 aromatase

Journal of inorganic biochemistry, 2018-07, Vol.184, p.79-87

2018

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Spin equilibrium and O2-binding kinetics of Mycobacterium tuberculosis CYP51 with mutations in the histidine–threonine dyad

Journal of inorganic biochemistry, 2014-07, Vol.136, p.81-91

2014

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Evidence for an Elevated Aspartate pKa in the Active Site of Human Aromatase

The Journal of biological chemistry, 2015-09, Vol.290 (2), p.1186-1196

2015

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Biophysical Characterization of Aptenodytes forsteri Cytochrome P450 19 (Aromatase)

The FASEB journal, 2018-04, Vol.32 (S1), p.796.22-796.22

2018

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Spin equilibrium and O sub(2)-binding kinetics of Mycobacterium tuberculosis CYP51 with mutations in the histidine-threonine dyad

Journal of inorganic biochemistry, 2014-07, Vol.136, p.81-91

2014

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Capture and Characterization of Dioxygen Reactive Intermediates in CYP51 Catalysis

Jennings, Gareth K

2012

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Design, Synthesis, and Biological Evaluation of New 1‑(Aryl‑1H‑pyrrolyl)(phenyl)methyl‑1H‑imidazole Derivatives as Antiprotozoal Agents

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1330-1347

2019

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Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes

Genome Biology, 2019-09, Vol.20 (1), p.187-31, Article 187

2019

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The genome of the stable fly, Stomoxys calcitrans, reveals potential mechanisms underlying reproduction, host interactions, and novel targets for pest control

BMC biology, 2021-03, Vol.19 (1), p.41-41, Article 41

2021

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Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Therapy on Liberation From Respiratory Support in Acutely Ill Children Admitted to Pediatric Critical Care Units: A Randomized Clinical Trial

JAMA : the journal of the American Medical Association, 2022-07, Vol.328 (2), p.162

2022

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Publisher Correction: The genome of the stable fly, Stomoxys calcitrans, reveals potential mechanisms underlying reproduction, host interactions, and novel targets for pest control

BMC biology, 2021-07, Vol.19 (1), p.1-150, Article 150

2021

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First-line antiretroviral therapy with a protease inhibitor versus non-nucleoside reverse transcriptase inhibitor and switch at higher versus low viral load in HIV-infected children: an open-label, randomised phase 2/3 trial

The Lancet infectious diseases, 2011-04, Vol.11 (4), p.273-283

2011

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Using CD4 percentage and age to optimize pediatric antiretroviral therapy initiation

Pediatrics (Evanston), 2014-10, Vol.134 (4), p.e1104-e1116

2014

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HIV-1 Drug Resistance and Second-Line Treatment in Children Randomized to Switch at Low Versus Higher RNA Thresholds

Journal of acquired immune deficiency syndromes (1999), 2015-09, Vol.70 (1), p.42-53

2015

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(1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride: a highly potent and selective 5-HT4 receptor antagonist derived from metoclopramide

Journal of medicinal chemistry, 1993-12, Vol.36 (25), p.4121-4123

1993

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Aggregation State and Neurotoxic Properties of Alzheimer Beta-Amyloid Peptide

Neurodegeneration (London, England), 1995-03, Vol.4 (1), p.23-32

1995

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N-Heterocyclic Carbene Capture by Cytochrome P450 3A4

Evidence for an elevated aspartate pK(a) in the active site of human aromatase

Noncovalent interactions dominate dynamic heme distortion in cytochrome P450 4B1

Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents

Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents

Rapid Chagas Disease Drug Target Discovery Using Directed Evolution in Drug-Sensitive Yeast

Biophysical characterization of Aptenodytes forsteri cytochrome P450 aromatase

Spin equilibrium and O2-binding kinetics of Mycobacterium tuberculosis CYP51 with mutations in the histidine–threonine dyad

Evidence for an Elevated Aspartate pKa in the Active Site of Human Aromatase

Biophysical Characterization of Aptenodytes forsteri Cytochrome P450 19 (Aromatase)

Spin equilibrium and O sub(2)-binding kinetics of Mycobacterium tuberculosis CYP51 with mutations in the histidine-threonine dyad

Capture and Characterization of Dioxygen Reactive Intermediates in CYP51 Catalysis

Design, Synthesis, and Biological Evaluation of New 1‑(Aryl‑1H‑pyrrolyl)(phenyl)methyl‑1H‑imidazole Derivatives as Antiprotozoal Agents

Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes

The genome of the stable fly, Stomoxys calcitrans, reveals potential mechanisms underlying reproduction, host interactions, and novel targets for pest control

Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Therapy on Liberation From Respiratory Support in Acutely Ill Children Admitted to Pediatric Critical Care Units: A Randomized Clinical Trial

Publisher Correction: The genome of the stable fly, Stomoxys calcitrans, reveals potential mechanisms underlying reproduction, host interactions, and novel targets for pest control

First-line antiretroviral therapy with a protease inhibitor versus non-nucleoside reverse transcriptase inhibitor and switch at higher versus low viral load in HIV-infected children: an open-label, randomised phase 2/3 trial

Using CD4 percentage and age to optimize pediatric antiretroviral therapy initiation

HIV-1 Drug Resistance and Second-Line Treatment in Children Randomized to Switch at Low Versus Higher RNA Thresholds

(1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride: a highly potent and selective 5-HT4 receptor antagonist derived from metoclopramide

Aggregation State and Neurotoxic Properties of Alzheimer Beta-Amyloid Peptide

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