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Disease candidate gene identification and prioritization using protein interaction networks

BMC bioinformatics, 2009-02, Vol.10 (1), p.73-73, Article 73

2009

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Changing Trends in Computational Drug Repositioning

Pharmaceuticals (Basel, Switzerland), 2018-06, Vol.11 (2), p.57

2018

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A comparison of anatomic and cellular transcriptome structures across 40 human brain diseases

PLoS biology, 2023-04, Vol.21 (4), p.e3002058-e3002058

2023

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Improved human disease candidate gene prioritization using mouse phenotype

BMC bioinformatics, 2007-10, Vol.8 (1), p.392-392, Article 392

2007

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ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

Nucleic acids research, 2009-07, Vol.37 (Web Server issue), p.W305-W311

2009

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Computational drug repositioning through heterogeneous network clustering

BMC systems biology, 2013-12, Vol.7 Suppl 5 (S5), p.S6-S6, Article S6

2013

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IL-31-Driven Skin Remodeling Involves Epidermal Cell Proliferation and Thickening That Lead to Impaired Skin-Barrier Function

PloS one, 2016-08, Vol.11 (8), p.e0161877-e0161877

2016

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ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems

Nucleic acids research, 2010-07, Vol.38 (Web Server issue), p.W96-W102

2010

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Pharmacological inhibition of apical sodium‐dependent bile acid transporter changes bile composition and blocks progression of sclerosing cholangitis in multidrug resistance 2 knockout mice

Hepatology (Baltimore, Md.), 2016-02, Vol.63 (2), p.512-523

2016

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Heat Shock Improves Sca‐1+ Stem Cell Survival and Directs Ischemic Cardiomyocytes Toward a Prosurvival Phenotype Via Exosomal Transfer: A Critical Role for HSF1/miR‐34a/HSP70 Pathway

Stem cells (Dayton, Ohio), 2014-02, Vol.32 (2), p.462-472

2014

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Gene‐disease associations identify a connectome with shared molecular pathways in human cholangiopathies

Hepatology (Baltimore, Md.), 2018-02, Vol.67 (2), p.676-689

2018

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Canonical genetic signatures of the adult human brain

Nature neuroscience, 2015-12, Vol.18 (12), p.1832-1844

2015

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Exploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome--clozapine-induced agranulocytosis as a case study

PLoS computational biology, 2011-03, Vol.7 (3), p.e1002016

2011

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Consensus Gene Co-Expression Network Analysis Identifies Novel Genes Associated with Severity of Fibrotic Lung Disease

International journal of molecular sciences, 2022-05, Vol.23 (10), p.5447

2022

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Systems biology of the autophagy-lysosomal pathway

Autophagy, 2011-05, Vol.7 (5), p.477-489

2011

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Gene expression signature for biliary atresia and a role for interleukin‐8 in pathogenesis of experimental disease

Hepatology (Baltimore, Md.), 2014-07, Vol.60 (1), p.211-223

2014

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gene2gauss : A multi-view gaussian gene embedding learner for analyzing transcriptomic networks

AMIA ... Annual Symposium proceedings, 2022, Vol.2022, p.206-215

2022

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Systems biology-based approaches to summarize and identify novel genes and pathways associated with acute and chronic postsurgical pain

Journal of clinical anesthesia, 2020-06, Vol.62, p.109738-109738, Article 109738

2020

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MGATRx: Discovering Drug Repositioning Candidates Using Multi-View Graph Attention

IEEE/ACM transactions on computational biology and bioinformatics, 2022-09, Vol.19 (5), p.2596-2604

2022

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The Protective Effects of IL-31RA Deficiency During Bleomycin-Induced Pulmonary Fibrosis

Frontiers in immunology, 2021-03, Vol.12, p.645717-645717

2021

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Data mining differential clinical outcomes associated with drug regimens using adverse event reporting data

Nature biotechnology, 2016-07, Vol.34 (7), p.697-700

2016

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Inhibition of Aurora Kinase B attenuates fibroblast activation and pulmonary fibrosis

EMBO molecular medicine, 2020-09, Vol.12 (9), p.e12131-n/a

2020

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Combination of esomeprazole and pirfenidone enhances antifibrotic efficacy in vitro and in a mouse model of TGFβ-induced lung fibrosis

Scientific reports, 2022-11, Vol.12 (1), p.20668-12, Article 20668

2022

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Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death

Journal of molecular and cellular cardiology, 2010-11, Vol.49 (5), p.841-850

2010

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Disease candidate gene identification and prioritization using protein interaction networks

Changing Trends in Computational Drug Repositioning

A comparison of anatomic and cellular transcriptome structures across 40 human brain diseases

Improved human disease candidate gene prioritization using mouse phenotype

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

Computational drug repositioning through heterogeneous network clustering

IL-31-Driven Skin Remodeling Involves Epidermal Cell Proliferation and Thickening That Lead to Impaired Skin-Barrier Function

ToppCluster: a multiple gene list feature analyzer for comparative enrichment clustering and network-based dissection of biological systems

Pharmacological inhibition of apical sodium‐dependent bile acid transporter changes bile composition and blocks progression of sclerosing cholangitis in multidrug resistance 2 knockout mice

Heat Shock Improves Sca‐1+ Stem Cell Survival and Directs Ischemic Cardiomyocytes Toward a Prosurvival Phenotype Via Exosomal Transfer: A Critical Role for HSF1/miR‐34a/HSP70 Pathway

Gene‐disease associations identify a connectome with shared molecular pathways in human cholangiopathies

Canonical genetic signatures of the adult human brain

Exploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome--clozapine-induced agranulocytosis as a case study

Consensus Gene Co-Expression Network Analysis Identifies Novel Genes Associated with Severity of Fibrotic Lung Disease

Systems biology of the autophagy-lysosomal pathway

Gene expression signature for biliary atresia and a role for interleukin‐8 in pathogenesis of experimental disease

gene2gauss : A multi-view gaussian gene embedding learner for analyzing transcriptomic networks

Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer

Systems biology-based approaches to summarize and identify novel genes and pathways associated with acute and chronic postsurgical pain

MGATRx: Discovering Drug Repositioning Candidates Using Multi-View Graph Attention

The Protective Effects of IL-31RA Deficiency During Bleomycin-Induced Pulmonary Fibrosis

Data mining differential clinical outcomes associated with drug regimens using adverse event reporting data

Inhibition of Aurora Kinase B attenuates fibroblast activation and pulmonary fibrosis

Combination of esomeprazole and pirfenidone enhances antifibrotic efficacy in vitro and in a mouse model of TGFβ-induced lung fibrosis

Synergistic effects of the GATA-4-mediated miR-144/451 cluster in protection against simulated ischemia/reperfusion-induced cardiomyocyte death

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