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Structural Modification of the Antidepressant Mianserin Suggests That Its Anti-inflammatory Activity May Be Independent of 5-Hydroxytryptamine Receptors

Frontiers in immunology, 2019-05, Vol.10, p.1167-1167

2019

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A GAL4-based yeast three-hybrid system for the identification of small molecule–target protein interactions

Biochemical pharmacology, 2002-05, Vol.63 (9), p.1619-1628

2002

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Enantioselective Synthesis of 3,6-Dihydro-1H-pyridin-2-ones: Unexpected Regioselectivity in the Palladium-Catalyzed Decarboxylative Carbonylation of 5-Vinyloxazolidin-2-ones

Journal of the American Chemical Society, 2000-03, Vol.122 (12), p.2944-2945

2000

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Structural and functional analyses of the second-generation integrase strand transfer inhibitor dolutegravir (S/GSK1349572)

Molecular pharmacology, 2011-10, Vol.80 (4), p.565-572

2011

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SK&F 97426-A: A Novel Bile Acid Sequestrant with Higher Affinities and Slower Dissociation Rates for Bile Acids in vitro Than Cholestyramine

Journal of pharmaceutical sciences, 1997-01, Vol.86 (1), p.76-81

1997

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The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin

Bioorganic & medicinal chemistry letters, 2001-03, Vol.11 (6), p.773-776

2001

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Octimibate, a potent non‐prostanoid inhibitor of platelet aggregation, acts via the prostacyclin receptor

British journal of pharmacology, 1991-01, Vol.102 (1), p.251-259

1991

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Structural and Functional Analyses of the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572)S

Molecular pharmacology, 2011-10, Vol.80 (4), p.565-572

2011

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Formation of zirconocene η2-imine complexes by rearrangement of cyclic iminoacyl complexes

Tetrahedron letters, 1992-09, Vol.33 (38), p.5655-5658

1992

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Discovery of 1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone (GSK163090), a Potent, Selective, and Orally Active 5-HT 1A/B/D Receptor Antagonist

Journal of medicinal chemistry, 2010-12, Vol.53 (23), p.8228-8240

2010

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Discovery of 1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone (GSK163090), a Potent, Selective, and Orally Active 5-HT1A/B/D Receptor Antagonist

Journal of medicinal chemistry, 2010-12, Vol.53 (23), p.8228-8240

2010

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Prospective use of molecular field points in ligand-based virtual screening: efficient identification of new reversible Cdc25 inhibitors

MedChemComm, 2013-08, Vol.4 (8), p.1148

2013

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Diaryl substituted pyrrolidinones and pyrrolones as 5-HT2C inhibitors: synthesis and biological evaluation

Bioorganic & medicinal chemistry letters, 2006-08, Vol.16 (15), p.3906-3912

2006

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Prospective use of molecular field points in ligand-based virtual screening: efficient identification of new reversible Cdc25 inhibitorsElectronic supplementary information (ESI) available: Details of computational and biological methods; screening results in the absence of detergent; calculated log D, solubility, ligand efficiency and lipophilic ligand efficiencies. See DOI: 10.1039/c3md00047h

2013-07

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Novel thymidine analogues via reaction of unprotected 5'-deoxy-5'-iodothymidine with dianions

Heterocycles, 1990-10, Vol.31 (10), p.1777-1780

1990

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Synthesis of cyclopentylamines using zirconium chemistry

Tetrahedron letters, 1994-02, Vol.35 (9), p.1445-1448

1994

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Synthesis and Biological Activity of Novel Cephalosporins Containing a (Z)-Vinyl Dimethylphosphonate Group

The Journal of Antibiotics, 1995/01/25, Vol.48(1), pp.73-82

1995

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ChemInform Abstract: An Approach to the Synthesis of 5,5-trans-Fused Lactam Analogues of β-Lactam Antibiotics

ChemInform, 2001-06, Vol.32 (23), p.no-no

2001

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Convergent Synthesis of Aminobicyclo[3.3.0]octenes Using Zirconium Chemistry An Unusual Anti-1,3-Amine Shift

Synlett, 1994-02, Vol.1994 (2), p.110-112

1994

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A GAL4-based yeast three-hybrid system for the identification of small molecule-target protein interactions

Biochemical pharmacology, 2002, Vol.63 (8), p.1619-1628

2002

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An approach to the synthesis of 5,5-trans-fused lactam analogues of β-lactam antibiotics

Perkin 1 : an international journal of organic and bio-organic chemistry, 2001-01 (1), p.21-25

2001

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ChemInform Abstract: Enantioselective Synthesis of 3,6-Dihydro-1H-pyridin-2-ones: Unexpected Regioselectivity in the Palladium-Catalyzed Decarboxylative Carbonylation of 5-Vinyloxazolidin-2-ones

ChemInform, 2000-06, Vol.31 (26), p.no-no

2000

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Diaryl substituted pyrrolidinones and pyrrolones as 5-HT2Cinhibitors : Synthesis and biological evaluation

Bioorganic & medicinal chemistry letters, 2006, Vol.16 (15), p.3906-3912

2006

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Structural Modification of the Antidepressant Mianserin Suggests That Its Anti-inflammatory Activity May Be Independent of 5-Hydroxytryptamine Receptors

A GAL4-based yeast three-hybrid system for the identification of small molecule–target protein interactions

Enantioselective Synthesis of 3,6-Dihydro-1H-pyridin-2-ones: Unexpected Regioselectivity in the Palladium-Catalyzed Decarboxylative Carbonylation of 5-Vinyloxazolidin-2-ones

Structural and functional analyses of the second-generation integrase strand transfer inhibitor dolutegravir (S/GSK1349572)

Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors

SK&F 97426-A: A Novel Bile Acid Sequestrant with Higher Affinities and Slower Dissociation Rates for Bile Acids in vitro Than Cholestyramine

The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin

Octimibate, a potent non‐prostanoid inhibitor of platelet aggregation, acts via the prostacyclin receptor

Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors

Structural and Functional Analyses of the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572)S

Formation of zirconocene η2-imine complexes by rearrangement of cyclic iminoacyl complexes

Discovery of 1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone (GSK163090), a Potent, Selective, and Orally Active 5-HT 1A/B/D Receptor Antagonist

Discovery of 1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone (GSK163090), a Potent, Selective, and Orally Active 5-HT1A/B/D Receptor Antagonist

Prospective use of molecular field points in ligand-based virtual screening: efficient identification of new reversible Cdc25 inhibitors

Diaryl substituted pyrrolidinones and pyrrolones as 5-HT2C inhibitors: synthesis and biological evaluation

Novel thymidine analogues via reaction of unprotected 5'-deoxy-5'-iodothymidine with dianions

Synthesis of cyclopentylamines using zirconium chemistry

Synthesis and Biological Activity of Novel Cephalosporins Containing a (Z)-Vinyl Dimethylphosphonate Group

ChemInform Abstract: An Approach to the Synthesis of 5,5-trans-Fused Lactam Analogues of β-Lactam Antibiotics

Convergent Synthesis of Aminobicyclo[3.3.0]octenes Using Zirconium Chemistry An Unusual Anti-1,3-Amine Shift

A GAL4-based yeast three-hybrid system for the identification of small molecule-target protein interactions

An approach to the synthesis of 5,5-trans-fused lactam analogues of β-lactam antibiotics

ChemInform Abstract: Enantioselective Synthesis of 3,6-Dihydro-1H-pyridin-2-ones: Unexpected Regioselectivity in the Palladium-Catalyzed Decarboxylative Carbonylation of 5-Vinyloxazolidin-2-ones

Diaryl substituted pyrrolidinones and pyrrolones as 5-HT2Cinhibitors : Synthesis and biological evaluation

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