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Dissociation of Transactivation from Transrepression by a Selective Glucocorticoid Receptor Agonist Leads to Separation of Therapeutic Effects from Side Effects

Proceedings of the National Academy of Sciences - PNAS, 2004-01, Vol.101 (1), p.227-232

2004

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New Approaches to Drug Discovery

1st ed. 2016, 2016

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Pharmacokinetics in Drug Discovery: An Exposure-Centred Approach to Optimising and Predicting Drug Efficacy and Safety

Handbook of experimental pharmacology, 2016, Vol.232, p.235-260

2016

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The last decade has seen many exciting new medicines being introduced to the market. Introduction

Handbook of experimental pharmacology, 2016, Vol.232, p.v

2016

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Discovery of the potent non-steroidal glucocorticoid receptor modulator BAY 1003803 as clinical candidate

Bioorganic & medicinal chemistry letters, 2020-08, Vol.30 (16), p.127298, Article 127298

2020

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Discovery of new selective glucocorticoid receptor agonist leads

Bioorganic & medicinal chemistry letters, 2017-02, Vol.27 (3), p.437-442

2017

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Translational In Vivo Models for Women’s Health: The Nonhuman Primate Endometrium—A Predictive Model for Assessing Steroid Receptor Modulators

Handbook of experimental pharmacology, 2016-01, Vol.232, p.191-202

2016

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Trends in Modern Drug Discovery

Handbook of experimental pharmacology, 2016, Vol.232, p.3-22

2016

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A Soluble Amyloid Fibril Segment to Study Aggregate Formation

ChemMedChem, 2007-01, Vol.2 (1), p.47-49

Jaroch, Stefan

2007

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Chemical Genomics: Small Molecule Probes to Study Cellular Function

1. Aufl., 2006

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Using Cheminformatics in Drug Discovery

Handbook of experimental pharmacology, 2016, Vol.232, p.139-168

2016

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Emerging Target Families: Intractable Targets

Handbook of experimental pharmacology, 2016, Vol.232, p.43-58

2016

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Correction to “Total Synthesis of (−)-Sarain A”

Journal of the American Chemical Society, 2018-04, Vol.140 (15), p.5319-5319

2018

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Abstract 4332: Discovery of BAY 1163877 - A pan-FGFR inhibitor: De novo structure-based design and lead optimization of benzothiophenyl-pyrrolotriazines

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4332-4332

2016

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Total Synthesis of (−)-Sarain A

Journal of the American Chemical Society, 2007-10, Vol.129 (39), p.11987-12002

2007

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Impact of Biomarkers on Personalized Medicine

Handbook of experimental pharmacology, 2016, Vol.232, p.285-311

2016

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Sources for Leads: Natural Products and Libraries

Handbook of experimental pharmacology, 2016, Vol.232, p.91-123

2016

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Implementation and Use of State-of-the-Art, Cell-Based In Vitro Assays

Handbook of experimental pharmacology, 2016, Vol.232, p.171-190

2016

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Predictive In Vivo Models for Oncology

Handbook of experimental pharmacology, 2016, Vol.232, p.203-221

2016

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Nonclinical Safety and Toxicology

Handbook of experimental pharmacology, 2016, Vol.232, p.261-283

2016

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Asymmetric Organocatalysis

ChemMedChem, 2007-09, Vol.2 (9), p.1261-1264

2007

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Modeling and Simulation of In Vivo Drug Effects

Handbook of experimental pharmacology, 2016, Vol.232, p.313-329

2016

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Putting small molecules in the lead

Nature chemical biology, 2005-09, Vol.1 (4), p.180-183

2005

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Discovery of quinolines as selective glucocorticoid receptor agonists

Bioorganic & medicinal chemistry letters, 2010-10, Vol.20 (19), p.5835-5838

2010

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In Vivo Target Validation Using Biological Molecules in Drug Development

Handbook of experimental pharmacology, 2016, Vol.232, p.59-70

2016

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Dissociation of Transactivation from Transrepression by a Selective Glucocorticoid Receptor Agonist Leads to Separation of Therapeutic Effects from Side Effects

New Approaches to Drug Discovery

Pharmacokinetics in Drug Discovery: An Exposure-Centred Approach to Optimising and Predicting Drug Efficacy and Safety

The last decade has seen many exciting new medicines being introduced to the market. Introduction

Discovery of the potent non-steroidal glucocorticoid receptor modulator BAY 1003803 as clinical candidate

Discovery of new selective glucocorticoid receptor agonist leads

Translational In Vivo Models for Women’s Health: The Nonhuman Primate Endometrium—A Predictive Model for Assessing Steroid Receptor Modulators

Trends in Modern Drug Discovery

A Soluble Amyloid Fibril Segment to Study Aggregate Formation

Chemical Genomics: Small Molecule Probes to Study Cellular Function

Using Cheminformatics in Drug Discovery

Emerging Target Families: Intractable Targets

Correction to “Total Synthesis of (−)-Sarain A”

Abstract 4332: Discovery of BAY 1163877 - A pan-FGFR inhibitor: De novo structure-based design and lead optimization of benzothiophenyl-pyrrolotriazines

Total Synthesis of (−)-Sarain A

Impact of Biomarkers on Personalized Medicine

Sources for Leads: Natural Products and Libraries

Implementation and Use of State-of-the-Art, Cell-Based In Vitro Assays

Predictive In Vivo Models for Oncology

Nonclinical Safety and Toxicology

Asymmetric Organocatalysis

Modeling and Simulation of In Vivo Drug Effects

Putting small molecules in the lead

Discovery of quinolines as selective glucocorticoid receptor agonists

In Vivo Target Validation Using Biological Molecules in Drug Development

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