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Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

Nature communications, 2016-04, Vol.7 (1), p.11262-11262, Article 11262

2016

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Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex

Cell reports (Cambridge), 2020-02, Vol.30 (8), p.2699-2711.e8

2020

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Investigating the Structure–Activity Relationship of 1,2,4-Triazine G‑Protein-Coupled Receptor 84 (GPR84) Antagonists

Journal of medicinal chemistry, 2022-08, Vol.65 (16), p.11270-11290

2022

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Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction

PloS one, 2021-11, Vol.16 (11), p.e0260283-e0260283

2021

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Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain

Nature communications, 2020-04, Vol.11 (1), p.2094-2094, Article 2094

2020

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Peptide Scanning for Studying Structure-Activity Relationships in Drug Discovery

Chemical biology & drug design, 2013-01, Vol.81 (1), p.148-165

2013

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A heme-binding domain controls regulation of ATP-dependent potassium channels

Proceedings of the National Academy of Sciences - PNAS, 2016-04, Vol.113 (14), p.3785-3790

2016

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Enzymatically-stable oxetane-based dipeptide hydrogels

Chemical communications (Cambridge, England), 2018, Vol.54 (14), p.1793-1796

2018

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Rotamer-Controlled Dual Emissive α‑Amino Acids

Organic letters, 2023-08, Vol.25 (31), p.5844-5849

2023

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Positional Scanning for Peptide Secondary Structure by Systematic Solid-Phase Synthesis of Amino Lactam Peptides

Journal of the American Chemical Society, 2009-06, Vol.131 (22), p.7917-7927

2009

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Development of Bifunctional, Raman Active Diyne‐Girder Stapled α‐Helical Peptides

Chemistry : a European journal, 2023-07, Vol.29 (41), p.e202300855-n/a

2023

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A short peptide that preferentially binds c-MYC G-quadruplex DNA

Chemical communications (Cambridge, England), 2020-08, Vol.56 (63), p.894-8943

2020

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Development of Potent PfCLK3 Inhibitors Based on TCMDC-135051 as a New Class of Antimalarials

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.9300-9315

2020

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Solid-Phase Synthesis of Oxetane Modified Peptides

Organic letters, 2017-06, Vol.19 (12), p.3303-3306

2017

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Friends or Foes? Emerging Impacts of Biological Toxins

Trends in biochemical sciences (Amsterdam. Regular ed.), 2019-04, Vol.44 (4), p.365-379

2019

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Synthesis and Fluorescent Properties of β‑Pyridyl α‑Amino Acids

Journal of organic chemistry, 2019-03, Vol.84 (5), p.2879-2890

2019

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Emerging peptide science in the United Kingdom

Peptide science (Hoboken, N.J.), 2021-01, Vol.113 (1), p.n/a

Jamieson, Andrew G.

2021

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Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence

Chemical communications (Cambridge, England), 2020-02, Vol.56 (12), p.1887-189

2020

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Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target

Science (American Association for the Advancement of Science), 2019-08, Vol.365 (6456)

2019

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Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex

The Journal of biological chemistry, 2015-07, Vol.290 (29), p.18237-18244

2015

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Development of Potent Pf CLK3 Inhibitors Based on TCMDC-135051 as a New Class of Antimalarials

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.9300-9315

2020

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Synthesis of HDAC Substrate Peptidomimetic Inhibitors Using Fmoc Amino Acids Incorporating Zinc-Binding Groups

Organic letters, 2019-05, Vol.21 (9), p.3178-3182

2019

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A 1,3-phenyl-linked hydantoin oligomer scaffold as a β-strand mimetic

Chemical communications (Cambridge, England), 2012-04, Vol.48 (31), p.3709-3711

2012

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Ether-Directed, Stereoselective Aza-Claisen Rearrangements: Synthesis of the Piperidine Alkaloid, α-Conhydrine

Organic letters, 2007-04, Vol.9 (8), p.1609-1611

2007

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Urotensin-II peptidomimetic incorporating a non-reducible 1,5-triazole disulfide bond reveals a pseudo-irreversible covalent binding mechanism to the urotensin G-protein coupled receptor

Organic & biomolecular chemistry, 2017-05, Vol.15 (21), p.4704-4710

2017

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Insights into the activation mechanism of class I HDAC complexes by inositol phosphates

Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex

Investigating the Structure–Activity Relationship of 1,2,4-Triazine G‑Protein-Coupled Receptor 84 (GPR84) Antagonists

Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction

Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain

Peptide Scanning for Studying Structure-Activity Relationships in Drug Discovery

A heme-binding domain controls regulation of ATP-dependent potassium channels

Enzymatically-stable oxetane-based dipeptide hydrogels

Rotamer-Controlled Dual Emissive α‑Amino Acids

Positional Scanning for Peptide Secondary Structure by Systematic Solid-Phase Synthesis of Amino Lactam Peptides

Development of Bifunctional, Raman Active Diyne‐Girder Stapled α‐Helical Peptides

A short peptide that preferentially binds c-MYC G-quadruplex DNA

Development of Potent PfCLK3 Inhibitors Based on TCMDC-135051 as a New Class of Antimalarials

Solid-Phase Synthesis of Oxetane Modified Peptides

Friends or Foes? Emerging Impacts of Biological Toxins

Synthesis and Fluorescent Properties of β‑Pyridyl α‑Amino Acids

Emerging peptide science in the United Kingdom

Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence

Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target

Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex

Development of Potent Pf CLK3 Inhibitors Based on TCMDC-135051 as a New Class of Antimalarials

Synthesis of HDAC Substrate Peptidomimetic Inhibitors Using Fmoc Amino Acids Incorporating Zinc-Binding Groups

A 1,3-phenyl-linked hydantoin oligomer scaffold as a β-strand mimetic

Ether-Directed, Stereoselective Aza-Claisen Rearrangements: Synthesis of the Piperidine Alkaloid, α-Conhydrine

Urotensin-II peptidomimetic incorporating a non-reducible 1,5-triazole disulfide bond reveals a pseudo-irreversible covalent binding mechanism to the urotensin G-protein coupled receptor

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