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CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia

The Journal of clinical investigation, 2013-06, Vol.123 (6), p.2395-2407

2013

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ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies

Science signaling, 2016-02, Vol.9 (415), p.ra17

2016

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Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis

The Journal of clinical investigation, 2012-06, Vol.122 (6), p.2066-2078

2012

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Inhibition of translation initiation factor eIF4a inactivates heat shock factor 1 (HSF1) and exerts anti-leukemia activity in AML

Leukemia, 2021-09, Vol.35 (9), p.2469-2481

2021

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Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models

Haematologica (Roma), 2020-03, Vol.105 (3), p.697-707

2020

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Oxygen sensing mesenchymal progenitors promote neo-vasculogenesis in a humanized mouse model in vivo

PloS one, 2012-09, Vol.7 (9), p.e44468-e44468

2012

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Reversal of Acquired Drug Resistance in FLT3-Mutated Acute Myeloid Leukemia Cells via Distinct Drug Combination Strategies

Clinical cancer research, 2014-05, Vol.20 (9), p.2363-2374

2014

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Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment

Blood, 2012-05, Vol.119 (21), p.4971-4980

2012

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FZR1 loss increases sensitivity to DNA damage and consequently promotes murine and human B-cell acute leukemia

Blood, 2017-04, Vol.129 (14), p.1958-1968

2017

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Protein kinase D1 inhibition interferes with mitosis progression

Journal of cellular physiology, 2019-11, Vol.234 (11), p.20510-20519

2019

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Synergistic Targeting of AML Stem/Progenitor Cells With IAP Antagonist Birinapant and Demethylating Agents

JNCI : Journal of the National Cancer Institute, 2014-02, Vol.106 (2), p.djt440

2014

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Uncovering the Role of RNA-Binding Protein hnRNP K in B-Cell Lymphomas

JNCI : Journal of the National Cancer Institute, 2020-01, Vol.112 (1), p.95-106

2020

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Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival

Haematologica (Roma), 2018-05, Vol.103 (5), p.810-821

2018

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SIK2 Is a Centrosome Kinase Required for Bipolar Mitotic Spindle Formation that Provides a Potential Target for Therapy in Ovarian Cancer

Cancer cell, 2010-08, Vol.18 (2), p.109-121

2010

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Exogenous mitochondrial transfer and endogenous mitochondrial fission facilitate AML resistance to OxPhos inhibition

Blood advances, 2021-10, Vol.5 (20), p.4233-4255

2021

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Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment

Cancer biology & therapy, 2012-08, Vol.13 (10), p.858-870

2012

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MDM2 Inhibitor, Nutlin 3a, Induces p53 Dependent Autophagy in Acute Leukemia by AMP Kinase Activation

PloS one, 2015-10, Vol.10 (10), p.e0139254-e0139254

2015

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AML-induced osteogenic differentiation in mesenchymal stromal cells supports leukemia growth

JCI insight, 2017-07, Vol.2 (13)

2017

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Extracellular calcium sensing receptor stimulation in human colonic epithelial cells induces intracellular calcium oscillations and proliferation inhibition

Journal of cellular physiology, 2010-10, Vol.225 (1), p.73-83

2010

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The novel combination of dual mTOR inhibitor AZD2014 and pan-PIM inhibitor AZD1208 inhibits growth in acute myeloid leukemia via HSF pathway suppression

Oncotarget, 2015-11, Vol.6 (35), p.37930-37947

2015

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Differential regulation of Pyk2 phosphorylation at Tyr-402 and Tyr-580 in intestinal epithelial cells: Roles of calcium, Src, Rho kinase, and the cytoskeleton

Cellular signalling, 2006-11, Vol.18 (11), p.1932-1940

2006

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Preferential Phosphorylation of Focal Adhesion Kinase Tyrosine 861 Is Critical for Mediating an Anti-apoptotic Response to Hyperosmotic Stress

The Journal of biological chemistry, 2007-04, Vol.282 (14), p.10370-10379

2007

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MHC class I and integrin ligation induce ERK activation via an mTORC2-dependent pathway

Biochemical and biophysical research communications, 2008-05, Vol.369 (2), p.781-787

2008

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FAK phosphorylation at Ser-843 inhibits Tyr-397 phosphorylation, cell spreading and migration

Journal of cellular physiology, 2007-02, Vol.210 (2), p.436-444

2007

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CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia

ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies

Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis

Inhibition of translation initiation factor eIF4a inactivates heat shock factor 1 (HSF1) and exerts anti-leukemia activity in AML

Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models

Oxygen sensing mesenchymal progenitors promote neo-vasculogenesis in a humanized mouse model in vivo

Reversal of Acquired Drug Resistance in FLT3-Mutated Acute Myeloid Leukemia Cells via Distinct Drug Combination Strategies

Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment

Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosome-like acute B-cell lymphoblastic leukemia

FZR1 loss increases sensitivity to DNA damage and consequently promotes murine and human B-cell acute leukemia

Protein kinase D1 inhibition interferes with mitosis progression

Synergistic Targeting of AML Stem/Progenitor Cells With IAP Antagonist Birinapant and Demethylating Agents

Uncovering the Role of RNA-Binding Protein hnRNP K in B-Cell Lymphomas

Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival

SIK2 Is a Centrosome Kinase Required for Bipolar Mitotic Spindle Formation that Provides a Potential Target for Therapy in Ovarian Cancer

Exogenous mitochondrial transfer and endogenous mitochondrial fission facilitate AML resistance to OxPhos inhibition

Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment

MDM2 Inhibitor, Nutlin 3a, Induces p53 Dependent Autophagy in Acute Leukemia by AMP Kinase Activation

AML-induced osteogenic differentiation in mesenchymal stromal cells supports leukemia growth

Extracellular calcium sensing receptor stimulation in human colonic epithelial cells induces intracellular calcium oscillations and proliferation inhibition

The novel combination of dual mTOR inhibitor AZD2014 and pan-PIM inhibitor AZD1208 inhibits growth in acute myeloid leukemia via HSF pathway suppression

Differential regulation of Pyk2 phosphorylation at Tyr-402 and Tyr-580 in intestinal epithelial cells: Roles of calcium, Src, Rho kinase, and the cytoskeleton

Preferential Phosphorylation of Focal Adhesion Kinase Tyrosine 861 Is Critical for Mediating an Anti-apoptotic Response to Hyperosmotic Stress

MHC class I and integrin ligation induce ERK activation via an mTORC2-dependent pathway

FAK phosphorylation at Ser-843 inhibits Tyr-397 phosphorylation, cell spreading and migration

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