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Synthesis of imidazo[1,5- a]pyridines from 1,1-dibromo-1-alkenes

Tetrahedron letters, 2010-02, Vol.51 (5), p.828-831

2010

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Total Synthesis of (±)-Alantrypinone by Hetero Diels−Alder Reaction

Journal of organic chemistry, 2004-01, Vol.69 (1), p.79-85

2004

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Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors

Bioorganic & medicinal chemistry, 2008-10, Vol.18 (20), p.5648-5652

2008

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Modifications of the isonipecotic acid fragment of SNS-032 : Analogs with improved permeability and lower efflux ratio

Bioorganic & medicinal chemistry, 2008-12, Vol.18 (23), p.6236-6239

2008

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A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties

Bioorganic & medicinal chemistry, 2008-11, Vol.18 (21), p.5763-5765

2008

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A Concise Total Synthesis of (±)-Alantrypinone by a Novel Hetero-Diels−Alder Reaction

Organic letters, 2003-09, Vol.5 (18), p.3205-3208

2003

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Optimization of novel reversible Bruton’s tyrosine kinase inhibitors identified using Tethering-fragment-based screens

Bioorganic & medicinal chemistry, 2019-07, Vol.27 (13), p.2905-2913

2019

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Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of novel reversible Bruton’s tyrosine kinase inhibitors

Bioorganic & medicinal chemistry, 2021-08, Vol.44, p.116275-116275, Article 116275

2021

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Syntheses of β,β-Difluorotryptamines

Journal of organic chemistry, 2003-04, Vol.68 (7), p.2798-2802

2003

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Syntheses of side-chain fluorinated biologically important imidazoles and indoles

Journal of Fluorine Chemistry, 2004-04, Vol.125 (4), p.501-508

2004

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Synthesis of ( E)- and ( Z)-α,β-difluorourocanic acid

Journal of fluorine chemistry, 2008-02, Vol.129 (2), p.112-118

2008

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Total synthesis of a dibromotyrosine alkaloid inhibitor of mycothiol S-conjugate amidase

Tetrahedron letters, 2004, Vol.45 (1), p.133-135

2004

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In vitro properties of antimicrobial bromotyrosine alkaloids

Journal of medical microbiology, 2006-04, Vol.55 (4), p.407-415

2006

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Syntheses of 6-fluoro- meta-tyrosine and of its metabolites

Journal of fluorine chemistry, 2002, Vol.115 (1), p.27-32

2002

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Convenient syntheses of biogenic aldehydes, 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde

Bioorganic chemistry, 2003-04, Vol.31 (2), p.191-197

2003

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Syntheses of E- and Z-2- and 4-fluorourocanic acids

Journal of fluorine chemistry, 2002-06, Vol.115 (2), p.137-142

2002

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Synthesis of the trifluoromethylated retinoial aromatic amide—4-[1-(5,6,7,8-tetrahydro-3-trifluoromethyl-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid

Journal of fluorine chemistry, 1999-07, Vol.96 (2), p.159-161

1999

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A Suzuki coupling approach to double bonds locked analogues of strobilurin A

Tetrahedron letters, 1996-11, Vol.37 (45), p.8213-8216

1996

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A suzuki coupling approach to trifluoromethyl derivative of targretin (LGD 1069)

Bioorganic & medicinal chemistry letters, 1997-08, Vol.7 (16), p.2117-2120

1997

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ChemInform Abstract: Synthesis of Imidazo[1,5-a]pyridines from 1,1-Dibromo-1-alkenes

ChemInform, 2010-05, Vol.41 (20), p.no-no

2010

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First synthesis of ortho-trifluoromethylated aryl triflates

Journal of the Chemical Society, Perkin Transactions 1, 1997-10 (20), p.3053-3058

1997

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Total Synthesis of (.+-.)-Alantrypinone (I) by Hetero Diels-Alder Reaction

ChemInform, 2004-06, Vol.35 (22), p.no-no

2004

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Total Synthesis of a Dibromotyrosine Alkaloid Inhibitor of Mycothiol S-Conjugate Amidase

ChemInform, 2004-04, Vol.35 (15), p.no-no

2004

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A Concise Total Synthesis of (.+-.)-Alantrypinone by a Novel Hetero-Diels-Alder Reaction

ChemInform, 2003-12, Vol.34 (50), p.no-no

2003

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ChemInform Abstract: Synthesis of (E)- and (Z)-α,β-Difluorourocanic Acid

ChemInform, 2008-05, Vol.39 (21), p.no-no

2008

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Synthesis of imidazo[1,5- a]pyridines from 1,1-dibromo-1-alkenes

Total Synthesis of (±)-Alantrypinone by Hetero Diels−Alder Reaction

Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors

Modifications of the isonipecotic acid fragment of SNS-032 : Analogs with improved permeability and lower efflux ratio

A diaminocyclohexyl analog of SNS-032 with improved permeability and bioavailability properties

A Concise Total Synthesis of (±)-Alantrypinone by a Novel Hetero-Diels−Alder Reaction

Optimization of novel reversible Bruton’s tyrosine kinase inhibitors identified using Tethering-fragment-based screens

Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of novel reversible Bruton’s tyrosine kinase inhibitors

Syntheses of β,β-Difluorotryptamines

Syntheses of side-chain fluorinated biologically important imidazoles and indoles

Synthesis of ( E)- and ( Z)-α,β-difluorourocanic acid

Total synthesis of a dibromotyrosine alkaloid inhibitor of mycothiol S-conjugate amidase

In vitro properties of antimicrobial bromotyrosine alkaloids

Syntheses of 6-fluoro- meta-tyrosine and of its metabolites

Convenient syntheses of biogenic aldehydes, 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde

Syntheses of E- and Z-2- and 4-fluorourocanic acids

Synthesis of the trifluoromethylated retinoial aromatic amide—4-[1-(5,6,7,8-tetrahydro-3-trifluoromethyl-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid

A Suzuki coupling approach to double bonds locked analogues of strobilurin A

A suzuki coupling approach to trifluoromethyl derivative of targretin (LGD 1069)

ChemInform Abstract: Synthesis of Imidazo[1,5-a]pyridines from 1,1-Dibromo-1-alkenes

First synthesis of ortho-trifluoromethylated aryl triflates

Total Synthesis of (.+-.)-Alantrypinone (I) by Hetero Diels-Alder Reaction

Total Synthesis of a Dibromotyrosine Alkaloid Inhibitor of Mycothiol S-Conjugate Amidase

A Concise Total Synthesis of (.+-.)-Alantrypinone by a Novel Hetero-Diels-Alder Reaction

ChemInform Abstract: Synthesis of (E)- and (Z)-α,β-Difluorourocanic Acid

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