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Glycolytic suppression dramatically changes the intracellular metabolic profile of multiple cancer cell lines in a mitochondrial metabolism-dependent manner

Scientific reports, 2019-12, Vol.9 (1), p.18699-15, Article 18699

2019

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Lipopolysaccharide administration increases the susceptibility of mitochondrial permeability transition pore opening via altering adenine nucleotide translocase conformation in the mouse liver

The Journal of Toxicological Sciences, 2023, Vol.48(2), pp.65-73

2023

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Role of respiratory uncoupling in drug-induced mitochondrial permeability transition

Toxicology and applied pharmacology, 2021-09, Vol.427, p.115659, Article 115659

2021

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Investigation of energy metabolic dynamism in hyperthermia-resistant ovarian and uterine cancer cells under heat stress

Scientific reports, 2021-07, Vol.11 (1), p.14726-14726, Article 14726

2021

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Conjugation of human serum albumin and flucloxacillin provokes specific immune response in HLA-B57:01 transgenic mice

Immunology letters, 2022-09, Vol.249, p.5-11

2022

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TARC/CCL17 Expression Is Associated with CD8+ T Cell Recruitment in Abacavir-Induced Skin Hypersensitivity in HLA-Transgenic Mice

Biological and Pharmaceutical Bulletin, 2022/09/01, Vol.45(9), pp.1347-1353

2022

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Altered intracellular signaling by imatinib increases the anti‐cancer effects of tyrosine kinase inhibitors in chronic myelogenous leukemia cells

Cancer science, 2018-01, Vol.109 (1), p.121-131

2018

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Decreased extra-renal urate excretion is a common cause of hyperuricemia

Nature communications, 2012-04, Vol.3 (1), p.764-764, Article 764

2012

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Detection of Abacavir-Induced Structural Alterations in Human Leukocyte Antigen-B57 : 01 Using Phage Display

Biological and Pharmaceutical Bulletin, 2020/06/01, Vol.43(6), pp.1007-1015

2020

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Increased susceptibility to troglitazone-induced mitochondrial permeability transition in type 2 diabetes mellitus model rat

The Journal of Toxicological Sciences, 2018, Vol.43(5), pp.339-351

2018

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Hypoxia/reoxygenation exacerbates drug-induced cytotoxicity by opening mitochondrial permeability transition pore: Possible application for toxicity screening

Toxicology in vitro, 2020-09, Vol.67, p.104889, Article 104889

2020

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Assessment of mitochondrial dysfunction-related, drug-induced hepatotoxicity in primary rat hepatocytes

Toxicology and applied pharmacology, 2016-07, Vol.302, p.23-30

2016

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Identification of Bile Acids Responsible for Inhibiting the Bile Salt Export Pump, Leading to Bile Acid Accumulation and Cell Toxicity in Rat Hepatocytes

Journal of pharmaceutical sciences, 2017-09, Vol.106 (9), p.2412-2419

2017

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The PD1 inhibitory pathway and mature dendritic cells contribute to abacavir hypersensitivity in human leukocyte antigen transgenic PD1 knockout mice

Toxicology (Amsterdam), 2021-11, Vol.463, p.152971-152971, Article 152971

2021

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A toll-like receptor 9 agonist sensitizes mice to mitochondrial dysfunction-induced hepatic apoptosis via the Fas/FasL pathway

Archives of toxicology, 2019-06, Vol.93 (6), p.1573-1584

2019

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Successful energy shift from glycolysis to mitochondrial oxidative phosphorylation in freshly isolated hepatocytes from humanized mice liver

Toxicology in vitro, 2020-06, Vol.65, p.104785-104785, Article 104785

2020

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siRNA delivery to lymphatic endothelial cells via ApoE-mediated uptake by lipid nanoparticles

Journal of controlled release, 2023-01, Vol.353, p.125-133

2023

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Autophagy is an important metabolic pathway to determine leukemia cell survival following suppression of the glycolytic pathway

Biochemical and biophysical research communications, 2016-05, Vol.474 (1), p.188-192

2016

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Prediction of the Clinical Risk of Drug-Induced Cholestatic Liver Injury Using an In Vitro Sandwich Cultured Hepatocyte Assay

Drug metabolism and disposition, 2015-11, Vol.43 (11), p.1760-1768

2015

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HLA transgenic mice: application in reproducing idiosyncratic drug toxicity

Drug metabolism reviews, 2020-10, Vol.52 (4), p.540-567

2020

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Mild depolarization is involved in troglitazone-induced liver mitochondrial membrane permeability transition via mitochondrial iPLA2 activation

The Journal of Toxicological Sciences, 2019, Vol.44(11), pp.811-820

2019

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Aldo-keto reductase inhibitors increase the anticancer effects of tyrosine kinase inhibitors in chronic myelogenous leukemia

Journal of pharmacological sciences, 2021-09, Vol.147 (1), p.1-8

2021

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Evaluation of Parent- and Metabolite-Induced Mitochondrial Toxicities Using CYP-Introduced HepG2 cells

Journal of pharmaceutical sciences, 2021-09, Vol.110 (9), p.3306-3312

2021

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Drug-induced altered self-presentation increases tumor immunogenicity

Biomedicine & pharmacotherapy, 2023-09, Vol.165, p.115241-115241, Article 115241

2023

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Weak complex formation of adverse drug reaction-associated HLA B57, B58, and B15 molecules

Toxicology in vitro, 2022-08, Vol.82, p.105383, Article 105383

2022

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Glycolytic suppression dramatically changes the intracellular metabolic profile of multiple cancer cell lines in a mitochondrial metabolism-dependent manner

Lipopolysaccharide administration increases the susceptibility of mitochondrial permeability transition pore opening via altering adenine nucleotide translocase conformation in the mouse liver

Role of respiratory uncoupling in drug-induced mitochondrial permeability transition

Investigation of energy metabolic dynamism in hyperthermia-resistant ovarian and uterine cancer cells under heat stress

Conjugation of human serum albumin and flucloxacillin provokes specific immune response in HLA-B57:01 transgenic mice

TARC/CCL17 Expression Is Associated with CD8+ T Cell Recruitment in Abacavir-Induced Skin Hypersensitivity in HLA-Transgenic Mice

Altered intracellular signaling by imatinib increases the anti‐cancer effects of tyrosine kinase inhibitors in chronic myelogenous leukemia cells

Decreased extra-renal urate excretion is a common cause of hyperuricemia

Detection of Abacavir-Induced Structural Alterations in Human Leukocyte Antigen-B57 : 01 Using Phage Display

Increased susceptibility to troglitazone-induced mitochondrial permeability transition in type 2 diabetes mellitus model rat

Hypoxia/reoxygenation exacerbates drug-induced cytotoxicity by opening mitochondrial permeability transition pore: Possible application for toxicity screening

Assessment of mitochondrial dysfunction-related, drug-induced hepatotoxicity in primary rat hepatocytes

Identification of Bile Acids Responsible for Inhibiting the Bile Salt Export Pump, Leading to Bile Acid Accumulation and Cell Toxicity in Rat Hepatocytes

The PD1 inhibitory pathway and mature dendritic cells contribute to abacavir hypersensitivity in human leukocyte antigen transgenic PD1 knockout mice

A toll-like receptor 9 agonist sensitizes mice to mitochondrial dysfunction-induced hepatic apoptosis via the Fas/FasL pathway

Successful energy shift from glycolysis to mitochondrial oxidative phosphorylation in freshly isolated hepatocytes from humanized mice liver

siRNA delivery to lymphatic endothelial cells via ApoE-mediated uptake by lipid nanoparticles

Autophagy is an important metabolic pathway to determine leukemia cell survival following suppression of the glycolytic pathway

Prediction of the Clinical Risk of Drug-Induced Cholestatic Liver Injury Using an In Vitro Sandwich Cultured Hepatocyte Assay

HLA transgenic mice: application in reproducing idiosyncratic drug toxicity

Mild depolarization is involved in troglitazone-induced liver mitochondrial membrane permeability transition via mitochondrial iPLA2 activation

Aldo-keto reductase inhibitors increase the anticancer effects of tyrosine kinase inhibitors in chronic myelogenous leukemia

Evaluation of Parent- and Metabolite-Induced Mitochondrial Toxicities Using CYP-Introduced HepG2 cells

Drug-induced altered self-presentation increases tumor immunogenicity

Weak complex formation of adverse drug reaction-associated HLA B57, B58, and B15 molecules

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