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Cyclodextrin induces calcium-dependent lysosomal exocytosis

PloS one, 2010-11, Vol.5 (11), p.e15054-e15054

2010

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Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth

The Journal of clinical investigation, 2017-06, Vol.127 (6), p.2081-2090

2017

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PKC activation in Niemann pick C1 cells restores subcellular cholesterol transport

PloS one, 2013-08, Vol.8 (8), p.e74169-e74169

2013

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Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe

The Journal of clinical investigation, 2007-07, Vol.117 (7), p.1968-1978

2007

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The Differences Between Childhood and Adult Onset Antiphospholipid Syndrome

Frontiers in pediatrics, 2018-11, Vol.6, p.362-362

2018

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Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome

PloS one, 2016-06, Vol.11 (6), p.e0156407-e0156407

2016

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Inactivation of NPC1L1 Causes Multiple Lipid Transport Defects and Protects against Diet-induced Hypercholesterolemia

The Journal of biological chemistry, 2005-04, Vol.280 (13), p.12710-12720

2005

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MLN64 transport to the late endosome is regulated by binding to 14-3-3 via a non-canonical binding site

PloS one, 2012-04, Vol.7 (4), p.e34424

2012

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How we diagnose the antiphospholipid syndrome

Blood, 2009-01, Vol.113 (5), p.985-994

2009

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Incidence of Antiphospholipid Syndrome: Is Estimation Currently Possible?

European journal of rheumatology, 2023-01, Vol.10 (1), p.39-44

2023

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Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer

Cancer research (Chicago, Ill.), 2018-04, Vol.78 (8), p.2065-2080

2018

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An “Exacerbate-reverse” Strategy in Yeast Identifies Histone Deacetylase Inhibition as a Correction for Cholesterol and Sphingolipid Transport Defects in Human Niemann-Pick Type C Disease

The Journal of biological chemistry, 2011-07, Vol.286 (27), p.23842-23851

2011

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Naturally occurring free thiols within β2-glycoprotein I in vivo: nitrosylation, redox modification by endothelial cells, and regulation of oxidative stress–induced cell injury

Blood, 2010-09, Vol.116 (11), p.1961-1970

2010

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Hydroxychloroquine Protects against Cardiac Ischaemia/Reperfusion Injury In Vivo via Enhancement of ERK1/2 Phosphorylation

PloS one, 2015-12, Vol.10 (12), p.e0143771-e0143771

2015

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Oxidation of β2-glycoprotein I associates with IgG antibodies to domain I in patients with antiphospholipid syndrome

PloS one, 2017-10, Vol.12 (10), p.e0186513-e0186513

2017

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Pubertal timing after neonatal diethylstilbestrol exposure in female rats: Neuroendocrine vs peripheral effects and additive role of prenatal food restriction

Reproductive toxicology (Elmsford, N.Y.), 2014-04, Vol.44, p.63-72

2014

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Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction

iScience, 2022-09, Vol.25 (9), p.104941-104941, Article 104941

2022

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Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8

Journal of lipid research, 2009-02, Vol.50 (2), p.293-300

2009

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Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice

American journal of physiology: Gastrointestinal and liver physiology, 2008-10, Vol.295 (4), p.G776-G783

2008

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Niemann-Pick C1-like 1 is required for an LXR agonist to raise plasma HDL cholesterol in mice

Arteriosclerosis, thrombosis, and vascular biology, 2008-03, Vol.28 (3), p.448

2008

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Antiphospholipid antibodies enhance rat neonatal cardiomyocyte apoptosis in an in vitro hypoxia/reoxygenation injury model via p38 MAPK

Cell death & disease, 2017-01, Vol.8 (1), p.e2549-e2549

2017

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Treatment prescribing patterns in patients with juvenile idiopathic arthritis (JIA): Analysis from the UK Childhood Arthritis Prospective Study (CAPS)

Seminars in arthritis and rheumatism, 2016-10, Vol.46 (2), p.190-195

2016

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PEGylated Domain I of Beta-2-Glycoprotein I Inhibits the Binding, Coagulopathic, and Thrombogenic Properties of IgG From Patients With the Antiphospholipid Syndrome

Frontiers in immunology, 2018-10, Vol.9, p.2413-2413

2018

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NPC1 late endosomes contain elevated levels of non-esterified ('free') fatty acids and an abnormally glycosylated form of the NPC2 protein

Biochemical journal, 2005-09, Vol.390 (Pt 2), p.549-561

2005

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Endosomal Accumulation of Toll-Like Receptor 4 Causes Constitutive Secretion of Cytokines and Activation of Signal Transducers and Activators of Transcription in Niemann-Pick Disease Type C (NPC) Fibroblasts: A Potential Basis for Glial Cell Activation in the NPC Brain

The Journal of neuroscience, 2007-02, Vol.27 (8), p.1879-1891

2007

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Cyclodextrin induces calcium-dependent lysosomal exocytosis

Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth

PKC activation in Niemann pick C1 cells restores subcellular cholesterol transport

Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe

The Differences Between Childhood and Adult Onset Antiphospholipid Syndrome

Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome

Inactivation of NPC1L1 Causes Multiple Lipid Transport Defects and Protects against Diet-induced Hypercholesterolemia

MLN64 transport to the late endosome is regulated by binding to 14-3-3 via a non-canonical binding site

How we diagnose the antiphospholipid syndrome

Incidence of Antiphospholipid Syndrome: Is Estimation Currently Possible?

Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer

An “Exacerbate-reverse” Strategy in Yeast Identifies Histone Deacetylase Inhibition as a Correction for Cholesterol and Sphingolipid Transport Defects in Human Niemann-Pick Type C Disease

Naturally occurring free thiols within β2-glycoprotein I in vivo: nitrosylation, redox modification by endothelial cells, and regulation of oxidative stress–induced cell injury

Hydroxychloroquine Protects against Cardiac Ischaemia/Reperfusion Injury In Vivo via Enhancement of ERK1/2 Phosphorylation

Oxidation of β2-glycoprotein I associates with IgG antibodies to domain I in patients with antiphospholipid syndrome

Pubertal timing after neonatal diethylstilbestrol exposure in female rats: Neuroendocrine vs peripheral effects and additive role of prenatal food restriction

Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction

Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8

Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice

Niemann-Pick C1-like 1 is required for an LXR agonist to raise plasma HDL cholesterol in mice

Antiphospholipid antibodies enhance rat neonatal cardiomyocyte apoptosis in an in vitro hypoxia/reoxygenation injury model via p38 MAPK

Treatment prescribing patterns in patients with juvenile idiopathic arthritis (JIA): Analysis from the UK Childhood Arthritis Prospective Study (CAPS)

PEGylated Domain I of Beta-2-Glycoprotein I Inhibits the Binding, Coagulopathic, and Thrombogenic Properties of IgG From Patients With the Antiphospholipid Syndrome

NPC1 late endosomes contain elevated levels of non-esterified ('free') fatty acids and an abnormally glycosylated form of the NPC2 protein

Endosomal Accumulation of Toll-Like Receptor 4 Causes Constitutive Secretion of Cytokines and Activation of Signal Transducers and Activators of Transcription in Niemann-Pick Disease Type C (NPC) Fibroblasts: A Potential Basis for Glial Cell Activation in the NPC Brain

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