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Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling

Nature communications, 2021-03, Vol.12 (1), p.1426-1426, Article 1426

2021

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Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer

Cancer research (Chicago, Ill.), 2012-07, Vol.72 (14), p.3457-3462

2012

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Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer

Proceedings of the National Academy of Sciences - PNAS, 2019-01, Vol.116 (2), p.631-640

2019

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Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer

Cancer research (Chicago, Ill.), 2014-04, Vol.74 (8), p.2270-2282

2014

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A phase I study of niclosamide in combination with enzalutamide in men with castration-resistant prostate cancer

PloS one, 2018-06, Vol.13 (6), p.e0198389

2018

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Androgen receptor variants occur frequently in castration resistant prostate cancer metastases

PloS one, 2011-11, Vol.6 (11), p.e27970-e27970

2011

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Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Prostate Cancer

European urology, 2016-10, Vol.70 (4), p.599-608

2016

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Androgen Receptor Signaling and Metabolic and Cellular Plasticity During Progression to Castration Resistant Prostate Cancer

Frontiers in oncology, 2020-10, Vol.10, p.580617-580617

2020

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Truncation and constitutive activation of the androgen receptor by diverse genomic rearrangements in prostate cancer

Nature communications, 2016-11, Vol.7 (1), p.13668-13668, Article 13668

2016

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Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

The Journal of clinical investigation, 2010-08, Vol.120 (8), p.2715-2730

2010

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Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC)

Clinical cancer research, 2018-07, Vol.24 (13), p.3149-3162

2018

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Molecular Pathways: Targeting Resistance in the Androgen Receptor for Therapeutic Benefit

Clinical cancer research, 2014-02, Vol.20 (4), p.791-798

2014

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BET Bromodomain Inhibitors Enhance Efficacy and Disrupt Resistance to AR Antagonists in the Treatment of Prostate Cancer

Molecular cancer research, 2016-04, Vol.14 (4), p.324-331

2016

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Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy

Oncotarget, 2014-03, Vol.5 (6), p.1646-1656

2014

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Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells

Cancer research (Chicago, Ill.), 2016-05, Vol.76 (9), p.2731-2742

2016

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Diverse AR Gene Rearrangements Mediate Resistance to Androgen Receptor Inhibitors in Metastatic Prostate Cancer

Clinical cancer research, 2020-04, Vol.26 (8), p.1965-1976

2020

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Novel Androgen Receptor Coregulator GRHL2 Exerts Both Oncogenic and Antimetastatic Functions in Prostate Cancer

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13), p.3417-3430

2017

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Perturbation of NK cell peripheral homeostasis accelerates prostate carcinoma metastasis

The Journal of clinical investigation, 2013-10, Vol.123 (10), p.4410-4422

2013

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Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (11), p.4251-4256

2014

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The potential of AR-V7 as a therapeutic target

Expert opinion on therapeutic targets, 2018-03, Vol.22 (3), p.201-216

2018

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The effects of aging on the molecular and cellular composition of the prostate microenvironment

PloS one, 2010-09, Vol.5 (9), p.e12501

2010

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Aging‐related alterations in the extracellular matrix modulate the microenvironment and influence tumor progression

International journal of cancer, 2010-12, Vol.127 (12), p.2739-2748

2010

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Expression of androgen receptor splice variants in clinical breast cancers

Oncotarget, 2015-12, Vol.6 (42), p.44728-44744

2015

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Taxane Resistance in Prostate Cancer Mediated by AR-Independent GATA2 Regulation of IGF2

Cancer cell, 2015-02, Vol.27 (2), p.158-159

2015

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Prostate cancer xenografts engineered from 3D precision-porous poly(2-hydroxyethyl methacrylate) hydrogels as models for tumorigenesis and dormancy escape

Biomaterials, 2014-09, Vol.35 (28), p.8164-8174

2014

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Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling

Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer

Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer

A phase I study of niclosamide in combination with enzalutamide in men with castration-resistant prostate cancer

Androgen receptor variants occur frequently in castration resistant prostate cancer metastases

Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Prostate Cancer

Androgen Receptor Signaling and Metabolic and Cellular Plasticity During Progression to Castration Resistant Prostate Cancer

Truncation and constitutive activation of the androgen receptor by diverse genomic rearrangements in prostate cancer

Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC)

Molecular Pathways: Targeting Resistance in the Androgen Receptor for Therapeutic Benefit

BET Bromodomain Inhibitors Enhance Efficacy and Disrupt Resistance to AR Antagonists in the Treatment of Prostate Cancer

Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy

Second-Generation HSP90 Inhibitor Onalespib Blocks mRNA Splicing of Androgen Receptor Variant 7 in Prostate Cancer Cells

Diverse AR Gene Rearrangements Mediate Resistance to Androgen Receptor Inhibitors in Metastatic Prostate Cancer

Novel Androgen Receptor Coregulator GRHL2 Exerts Both Oncogenic and Antimetastatic Functions in Prostate Cancer

Perturbation of NK cell peripheral homeostasis accelerates prostate carcinoma metastasis

Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer

The potential of AR-V7 as a therapeutic target

The effects of aging on the molecular and cellular composition of the prostate microenvironment

Aging‐related alterations in the extracellular matrix modulate the microenvironment and influence tumor progression

Expression of androgen receptor splice variants in clinical breast cancers

Taxane Resistance in Prostate Cancer Mediated by AR-Independent GATA2 Regulation of IGF2

Prostate cancer xenografts engineered from 3D precision-porous poly(2-hydroxyethyl methacrylate) hydrogels as models for tumorigenesis and dormancy escape

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