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Rational discovery of molecular glue degraders via scalable chemical profiling

Nature chemical biology, 2020-11, Vol.16 (11), p.1199-1207

2020

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Disturbed mitochondrial dynamics in CD8 + TILs reinforce T cell exhaustion

Nature immunology, 2020-12, Vol.21 (12), p.1540-1551

2020

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Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells

eLife, 2015-03, Vol.4 (Art. n°e06857)

2015

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Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

Nature communications, 2015-04, Vol.6 (1), p.6683-6683, Article 6683

2015

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Breast Cancer Classification Based on Proteotypes Obtained by SWATH Mass Spectrometry

Cell reports (Cambridge), 2019-07, Vol.28 (3), p.832-843.e7

2019

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Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype

Nature communications, 2023-11, Vol.14 (1), p.7908-7908, Article 7908

2023

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Publisher Correction: Rational discovery of molecular glue degraders via scalable chemical profiling

Nature chemical biology, 2021-03, Vol.17 (3), p.361-361

2021

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Identification of High-Impact cis-Regulatory Mutations Using Transcription Factor Specific Random Forest Models

PLoS computational biology, 2015-11, Vol.11 (11), p.e1004590-e1004590

2015

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Combined Proteomics and Transcriptomics Identifies Carboxypeptidase B1 and Nuclear Factor κB (NF-κB) Associated Proteins as Putative Biomarkers of Metastasis in Low Grade Breast Cancer

Molecular & cellular proteomics, 2015-07, Vol.14 (7), p.1814-1830

2015

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iRegulon and i‐cisTarget: Reconstructing Regulatory Networks Using Motif and Track Enrichment

Current Protocols in Bioinformatics, 2015-12, Vol.52 (1), p.2.16.1-2.16.39

2015

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Identification of cis-regulatory mutations generating de novo edges in personalized cancer gene regulatory networks

Genome medicine, 2017-08, Vol.9 (1), p.80-80, Article 80

2017

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i-cisTarget 2015 update: generalized cis-regulatory enrichment analysis in human, mouse and fly

Nucleic acids research, 2015-07, Vol.43 (W1), p.W57-W64

2015

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iRegulon: from a gene list to a gene regulatory network using large motif and track collections

PLoS computational biology, 2014-07, Vol.10 (7), p.e1003731-e1003731

2014

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SCENIC: single-cell regulatory network inference and clustering

Nature methods, 2017-11, Vol.14 (11), p.1083-1086

2017

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iRegulon: From a Gene List to a Gene Regulatory Network Using Large Motif and Track Collections: e1003731

PLoS computational biology, 2014-07, Vol.10 (7)

2014

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Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders

Nature chemical biology, 2023-03, Vol.19 (3), p.323-333

2023

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Acute BAF perturbation causes immediate changes in chromatin accessibility

Nature genetics, 2021-03, Vol.53 (3), p.269-278

2021

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The transcription factor Grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes

Nature genetics, 2018-07, Vol.50 (7), p.1011-1020

2018

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Selective Mediator dependence of cell-type-specifying transcription

Nature genetics, 2020-07, Vol.52 (7), p.719-727

2020

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Discovery of a DCAF11-dependent cyanoacrylamide-containing covalent degrader of BET-proteins

Bioorganic & medicinal chemistry letters, 2024-07, Vol.107, p.129779-129779, Article 129779

2024

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Targeted protein degradation via intramolecular bivalent glues

Nature (London), 2024-03, Vol.627 (8002), p.204-211

2024

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Immunoediting instructs tumor metabolic reprogramming to support immune evasion

Cell metabolism, 2023-01, Vol.35 (1), p.118-133.e7

2023

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Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP

Nature chemical biology, 2024-06

2024

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Identification of High-Impact cis -Regulatory Mutations Using Transcription Factor Specific Random Forest Models: e1004590

PLoS computational biology, 2015-11, Vol.11 (11)

2015

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The transcription factor Grainyhead primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes

Nature genetics, 2018-06, Vol.50 (7), p.1011-1020

2018

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Rational discovery of molecular glue degraders via scalable chemical profiling

Disturbed mitochondrial dynamics in CD8 + TILs reinforce T cell exhaustion

Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells

Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

Breast Cancer Classification Based on Proteotypes Obtained by SWATH Mass Spectrometry

Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype

Publisher Correction: Rational discovery of molecular glue degraders via scalable chemical profiling

Identification of High-Impact cis-Regulatory Mutations Using Transcription Factor Specific Random Forest Models

Combined Proteomics and Transcriptomics Identifies Carboxypeptidase B1 and Nuclear Factor κB (NF-κB) Associated Proteins as Putative Biomarkers of Metastasis in Low Grade Breast Cancer

iRegulon and i‐cisTarget: Reconstructing Regulatory Networks Using Motif and Track Enrichment

Identification of cis-regulatory mutations generating de novo edges in personalized cancer gene regulatory networks

i-cisTarget 2015 update: generalized cis-regulatory enrichment analysis in human, mouse and fly

iRegulon: from a gene list to a gene regulatory network using large motif and track collections

SCENIC: single-cell regulatory network inference and clustering

iRegulon: From a Gene List to a Gene Regulatory Network Using Large Motif and Track Collections: e1003731

Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders

Acute BAF perturbation causes immediate changes in chromatin accessibility

The transcription factor Grainy head primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes

Selective Mediator dependence of cell-type-specifying transcription

Discovery of a DCAF11-dependent cyanoacrylamide-containing covalent degrader of BET-proteins

Targeted protein degradation via intramolecular bivalent glues

Immunoediting instructs tumor metabolic reprogramming to support immune evasion

Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP

Identification of High-Impact cis -Regulatory Mutations Using Transcription Factor Specific Random Forest Models: e1004590

The transcription factor Grainyhead primes epithelial enhancers for spatiotemporal activation by displacing nucleosomes

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