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A Pharmacometric Approach to Substitute for a Conventional Dose-Finding Study in Rare Diseases: Example of Phase III Dose Selection for Emicizumab in Hemophilia A

Clinical pharmacokinetics, 2018-09, Vol.57 (9), p.1123-1134

2018

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A comprehensive review of the pharmacokinetics of approved therapeutic monoclonal antibodies in Japan: Are Japanese phase I studies still needed?

Journal of clinical pharmacology, 2014-05, Vol.54 (5), p.483-494

2014

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Risk of CYP2C9 induction analyzed by a relative factor approach with human hepatocytes

Drug metabolism and pharmacokinetics, 2019-10, Vol.34 (5), p.325-333

2019

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Modeling and Simulation of Orlistat to Predict Weight Loss and Weight Maintenance in Obesity Patients

DRUG METABOLISM AND PHARMACOKINETICS, 2014, Vol.29 (3), p.278-282

2014

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Population Pharmacokinetic-Pharmacodynamic Modeling and Simulation of Platelet Decrease Induced by Peg-interferon-alpha 2a

DRUG METABOLISM AND PHARMACOKINETICS, 2012, Vol.27 (6), p.614-620

2012

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Dosage Optimization of Nemolizumab Using Population Pharmacokinetic and Pharmacokinetic‐Pharmacodynamic Modeling and Simulation

Journal of clinical pharmacology, 2017-12, Vol.57 (12), p.1564-1572

2017

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Application of Modeling and Simulation to a Long-Term Clinical Trial: A Direct Comparison of Simulated Data and Data Actually Observed in Japanese Osteoporosis Patients Following 3-Year Ibandronate Treatment

Clinical pharmacokinetics, 2015-03, Vol.54 (3), p.295-304

2015

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Erratum to: Application of Modeling and Simulation to a Long-Term Clinical Trial: A Direct Comparison of Simulated Data and Data Actually Observed in Japanese Osteoporosis Patients Following 3-Year Ibandronate Treatment

Clinical pharmacokinetics, 2015-04, Vol.54 (4), p.455-455

2015

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The optimal oral dose selection of ibandronate in Japanese patients with osteoporosis based on pharmacokinetic and pharmacodynamic properties

European journal of drug metabolism and pharmacokinetics, 2016-04, Vol.41 (2), p.139-147

2016

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Effective use of modeling and simulation in designing bioequivalence and comparability studies of large-molecule compounds: the case of erythropoietin

International journal of clinical pharmacology and therapeutics, 2015-06, Vol.53 (6), p.488

2015

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Maxacalcitol Pharmacokinetic-Pharmacodynamic Modeling and Simulation for Secondary Hyperparathyroidism in Patients Receiving Maintenance Hemodialysis

Drug research, 2022-01, Vol.72 (1), p.23

2022

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Indications for a ceftriaxone dosing regimen in Japanese paediatric patients using population pharmacokinetic/pharmacodynamic analysis and simulation

Journal of pharmacy and pharmacology, 2011-01, Vol.63 (1), p.65-72

2011

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Target-mediated drug disposition model(TMDD model)

ファルマシア, 2018, Vol.54(5), pp.439_3-439_3

飯田, 理文

2018

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Time‐to‐event modelling of effect of codrituzumab on overall survival in patients with hepatocellular carcinoma

British journal of clinical pharmacology, 2018-05, Vol.84 (5), p.944-951

2018

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A comprehensive review of the pharmacokinetics of approved therapeutic monoclonal antibodies in Japan: Are Japanese phase I studies still needed?: The Journal of Clinical Pharmacology

Journal of clinical pharmacology, 2014-05, Vol.54 (5), p.483-494

2014

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Population pharmacokinetic-pharmacodynamic modelling and simulation of neutropenia induced by TP300, a novel topoisomerase I inhibitor

Journal of pharmacy and pharmacology, 2013-08, Vol.65 (8), p.1168-1178

2013

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高分子医薬品の体内動態

ファルマシア, 2018, Vol.54(5), pp.425-429

飯田, 理文

2018

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Population pharmacokinetic and pharmacodynamic modelling of the effects of nicorandil in the treatment of acute heart failure

British journal of clinical pharmacology, 2008-09, Vol.66 (3), p.352-365

2008

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The pharmacokinetics of ceftriaxone based on population pharmacokinetics and the prediction of efficacy in Japanese adults

European journal of drug metabolism and pharmacokinetics, 2009-04, Vol.34 (2), p.107-115

2009

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Validation Studies of Radioluminography II A Method for Monitoring Radioactive Contamination of Imaging Plates

Drug Metabolism and Pharmacokinetics, 1999/10/29, Vol.14(5), pp.367-370

1999

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Validation Studies of Radioluminography I: Measurement of Background Value

Drug Metabolism and Pharmacokinetics, 1998/12/25, Vol.13(6), pp.566-571

1998

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VALIDATION STUDIES OF RADIOLUMINOGRAPHY

Drug Metabolism and Pharmacokinetics, 1998/10/23, Vol.13(supplement), pp.130-131

1998

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Inhibition of the Hepatic Uptake of Paracetamol Sulphate by Anionic Compounds

Journal of pharmacy and pharmacology, 1997-08, Vol.49 (8), p.743-746

1997

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Disposition of Q-35(1): Absorption and Excretion after Single Administration of 14C-Q-35 in Rats

Drug Metabolism and Pharmacokinetics, 1995, Vol.10(5), pp.595-603

1995

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A novel pathway for formation of thiol metabolites and cysteine conjugates from cysteine conjugate sulphoxides

Biochemical pharmacology, 1993-10, Vol.46 (7), p.1113-1117

1993

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A Pharmacometric Approach to Substitute for a Conventional Dose-Finding Study in Rare Diseases: Example of Phase III Dose Selection for Emicizumab in Hemophilia A

A comprehensive review of the pharmacokinetics of approved therapeutic monoclonal antibodies in Japan: Are Japanese phase I studies still needed?

Risk of CYP2C9 induction analyzed by a relative factor approach with human hepatocytes

Modeling and Simulation of Orlistat to Predict Weight Loss and Weight Maintenance in Obesity Patients

Population Pharmacokinetic-Pharmacodynamic Modeling and Simulation of Platelet Decrease Induced by Peg-interferon-alpha 2a

Dosage Optimization of Nemolizumab Using Population Pharmacokinetic and Pharmacokinetic‐Pharmacodynamic Modeling and Simulation

Application of Modeling and Simulation to a Long-Term Clinical Trial: A Direct Comparison of Simulated Data and Data Actually Observed in Japanese Osteoporosis Patients Following 3-Year Ibandronate Treatment

Erratum to: Application of Modeling and Simulation to a Long-Term Clinical Trial: A Direct Comparison of Simulated Data and Data Actually Observed in Japanese Osteoporosis Patients Following 3-Year Ibandronate Treatment

The optimal oral dose selection of ibandronate in Japanese patients with osteoporosis based on pharmacokinetic and pharmacodynamic properties

Effective use of modeling and simulation in designing bioequivalence and comparability studies of large-molecule compounds: the case of erythropoietin

Maxacalcitol Pharmacokinetic-Pharmacodynamic Modeling and Simulation for Secondary Hyperparathyroidism in Patients Receiving Maintenance Hemodialysis

Indications for a ceftriaxone dosing regimen in Japanese paediatric patients using population pharmacokinetic/pharmacodynamic analysis and simulation

Target-mediated drug disposition model(TMDD model)

Time‐to‐event modelling of effect of codrituzumab on overall survival in patients with hepatocellular carcinoma

A comprehensive review of the pharmacokinetics of approved therapeutic monoclonal antibodies in Japan: Are Japanese phase I studies still needed?: The Journal of Clinical Pharmacology

Population pharmacokinetic-pharmacodynamic modelling and simulation of neutropenia induced by TP300, a novel topoisomerase I inhibitor

高分子医薬品の体内動態

Population pharmacokinetic and pharmacodynamic modelling of the effects of nicorandil in the treatment of acute heart failure

The pharmacokinetics of ceftriaxone based on population pharmacokinetics and the prediction of efficacy in Japanese adults

Validation Studies of Radioluminography II A Method for Monitoring Radioactive Contamination of Imaging Plates

Validation Studies of Radioluminography I: Measurement of Background Value

VALIDATION STUDIES OF RADIOLUMINOGRAPHY

Inhibition of the Hepatic Uptake of Paracetamol Sulphate by Anionic Compounds

Disposition of Q-35(1): Absorption and Excretion after Single Administration of 14C-Q-35 in Rats

A novel pathway for formation of thiol metabolites and cysteine conjugates from cysteine conjugate sulphoxides

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